From the recent reports out of California and other places, it appears that anophelines can be genetically modified so that (1) they are no longer susceptible to plasmodium infections, and (2) their progeny will be all males! If this can be developed for field use, it looks to me like it is the Beginning of the End of malaria in Africa. But I am an engineer with no experience in genetics. Do you think that this technique can be developed for field application?
anopheline malaria vectors
SUMMARY OF RECENT AFRICAN MALARIA DIALOGUE at BENTLEY UNIVERSITY on 21 MAY 2013
Fifteen of us attended from Bentley, BU, Yale, Harvard and MIT, and from Ghana, Sudan, Nigeria, Canada and US. Derek Willis from Columbia U also joined us via Skype.
The finding documents the presence of this mutant allele in Indonesia, and implies that selection pressure on the Anopheles population in this area has occurred. Further studies to determine the impact of the resistance allele on the efficacy of pyrethroids in control programmes are needed.