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chloroquine resistant

Anti-malarial activity and toxicity assessment of Himatanthus articulatus, a plant used to treat malaria in the Brazilian Amazon

March 31, 2015 - 17:38 -- Open Access
Author(s): 
Valdicley V Vale, Thyago C Vilhena, lávio De Vasconcelos, et al.
Reference: 
Malaria Journal 2015, 14:132 (27 March 2015)

The ethanol extract of H. articulatus proved to be promising as anti-malarial medicine and showed low toxicity.

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The antiplasmodial activity of norcantharidin analogs

October 22, 2010 - 06:34 -- Kabogo Ndegwa
Author(s): 
Joanna Bajsa, Adam McCluskey, Christopher P. Gordon, Scott G. Stewart, Timothy A. Hill, Rajnish Sahu, Stephen O. Duke, Babu L. Tekwani
Reference: 
Bioorganic & Medicinal Chemistry Letters, Volume 20, Issue 22, 15 November 2010, Pages 6688-6695

The antiplasmodial activities of sixty norcantharidin analogs were tested in vitro against a chloroquine sensitive (D6, Sierra Leone) and chloroquine resistant (W2) strains of Plasmodium falciparum.

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