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P. malariae

NOT Open Access | Various pfcrt and pfmdr1 Genotypes of Plasmodium falciparum Cocirculate with P. malariae, P. ovale spp., and P. vivax in Northern Angola

September 13, 2012 - 12:35 -- Kabogo Ndegwa
Cláudia Fançony, Dina Gamboa, Yuri Sebastião, Rachel Hallett, Colin Sutherland, José Carlos Sousa-Figueiredo, and Susana Vaz Nery
Antimicrob. Agents Chemother. October 2012 vol. 56 no. 10 5271-5277

MalariaWorldArtemisinin-based combination therapy for malaria has become widely available across Africa.

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Open Access | Clues to Evolution of the SERA Multigene Family in 18 Plasmodium Species

March 22, 2011 - 09:28 -- Kabogo Ndegwa
Nobuko Arisue, Satoru Kawai, Makoto Hirai, Nirianne M. Q. Palacpac, Mozhi Jia, Akira Kaneko, Kazuyuki Tanabe, Toshihiro Horii
PLoS ONE 6(3): e17775

SERA gene sequences were newly determined from 11 primate Plasmodium species including two human parasites, P. ovale and P. malariae, and the evolutionary history of SERA genes was analyzed together with 7 known species.

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Unresolved direction of host transfer of Plasmodium vivax v. P. simium and P. malariae v. P. brasilianum

December 20, 2010 - 09:34 -- Patrick Sampao
Loubna Tazi, Francisco J. Ayala
Infection, Genetics and Evolution, Volume 11, Issue 1, January 2011, Pages 209-221

Here, we investigate the phylogenies, haplotype networks, positive selection and genetic diversity among these parasite species by means of four genes. Human P. vivax and primate P. simium recently derived one from the other; at least two host transfers have occurred. Human P. malariae and primate P. brasilianum also have recently derived one from the other by lateral host transfer.

Detection of Plasmodium falciparum, P. vivax, P. ovale, and P. malariae Merozoite Surface Protein 1-p19 Antibodies in Human Malaria Patients and Experimentally Infected Nonhuman Primates

October 4, 2010 - 09:07 -- Kabogo Ndegwa
A. Scott Muerhoff, Larry G. Birkenmeyer, Ruthie Coffey, Bruce J. Dille, John W. Barnwell, William E. Collins, Joann S. Sullivan, George J. Dawson, and Suresh M. Desai
Clin. Vaccine Immunol. 2010;17 1631-1638

Approximately 3.2 billion people live in areas where malaria is endemic, and WHO estimates that 350 to 500 million malaria cases occur each year worldwide. This high prevalence, and the high frequency of international travel, creates significant risk for the exportation of malaria to countries where malaria is not endemic and for the introduction of malaria organisms into the blood supply.

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