It is important to have a good representation of the haplotypes circulating worldwide when implementing a vaccine, regardless of the geographic region of deployment since selective pressure plays an important role in structuring antigen diversity.
The evolution of different members of the Pvrbp2 family and their relatively high degree of polymorphism suggests that the proteins encoded by these genes are important for parasite survival and are under immune selection.
PvDBPII of Myanmar P. vivax isolates displays a high level of genetic polymorphism and is under selective pressure.
This was a sporadic case with no evidence of further local transmission, and no more cases have been reported in Attica up to August 2011, two years later.
Therefore here, we have investigated whether Pvs230 can be a TBV candidate using P. vivax samples obtained from Thailand.
This study provided further resolution of the population structure and evolution of P. vivax, especially in temperate/warm-temperate endemic areas of Asia.
We present here the sequences of large and small subunit rRNA (lsu and ssu rRNA) genes, sufB (ORF470) gene, RNA polymerase (rpo B, C) subunit genes and clpC (casienolytic protease) gene from the plastid genome of P. vivax.
We evaluated the safety of withholding antimalarial drugs from young Papua New Guinean children with negative RDT results in areas with high levels of both Plasmodium falciparum and P. vivax infections.
Although acute glomerulonephritis is a rare complication of Plasmodium falciparum malaria, it has not been reported in connection with Plasmodium vivax.
This analysis principally concerns biological aspects of dormancy in mammalian malaria, with particular reference to the hypnozoite.