Plasmodium vivax threatens nearly half the world's population and is a significant impediment to achievement of the millennium development goals.
Adherence of P. vivax-infected erythrocytes to glycosaminoglycans may contribute to the pathogenesis of vivax malaria and lead to intrauterine growth retardation.
The human malaria parasite Plasmodium vivax is globally widespread, causing high malaria morbidity.
Molecular tests are valuable tools for the confirmation of Plasmodium species and in detecting mixed infections in malaria endemic regions.
Among 25 cases in India during 2010-2011, associated conditions were renal failure, thrombocytopenia, jaundice, severe anemia, acute respiratory distress syndrome, shock, cerebral malaria, hypoglycemia, and death.
This is probably the first report showing genotypically Duffy-negative people who carry both FY*BES and FY*AES.
In this study, groups of C57BL/6J mice were immunized subcutaneously three times with VMP001 emulsified with synthetic TLR4 (GLA) or TLR7/8 (R848) agonist in stable emulsion (SE), a combination of the TLR4 and TLR7/8 agonists, or SE alone.
These findings demonstrate the potential use of TR markers for molecular epidemiology studies.
These results suggested a continual introduction of P. vivax from other population sources, probably North Korea.
In areas of low transmission intensity, such as in Cambodia, the analysis of longitudinal serological data enables a sensitive evaluation of transmission dynamics.