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Plasmodium vivax

Not Open Access |Epidemic Distribution and Variation of Plasmodium falciparum and Plasmodium vivax Malaria in Hainan, China during 1995–2008

October 10, 2012 - 15:56 -- Patrick Sampao
Author(s): 
Dan Xiao, Yong Long, Shanqing Wang, Kejian Wu, Dezhong Xu, Haitao Li, Guangze Wang and Yongping Yan
Reference: 
Am J Trop Med Hyg 2012 87:646-654

MalariaWorldIn this study, we determined the spatio-temporal distribution and variation of Plasmodium falciparum and Plasmodium vivax malaria in Hainan during 1995–2008 by using wavelet and cluster quantitative approaches.

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Duffy Phenotype and Plasmodium vivax Infections in Humans and Apes, Africa

October 1, 2012 - 17:40 -- Patrick Sampao
Author(s): 
R.L. Culleton and P.E. Ferreira
Reference: 
Emerging Infectious Diseases, October 2012

MalariaWorldThese findings are supported by a report from Madagascar (where the human population is composed of a mixture of Duffy-positive and Duffy-negative persons), in which 42 (8.8%) of 476 Duffy-negative persons who had symptoms of malaria were reported to be positive for P. vivax by both microscopy and PCR.

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NOT Open Access | Dissection of the Plasmodium vivax reticulocyte binding-like proteins (PvRBPs)

September 18, 2012 - 07:56 -- Kabogo Ndegwa
Author(s): 
Jian Li, Eun-Taek Han
Reference: 
Biochemical and Biophysical Research Communications Volume 426, Issue 1, 14 September 2012, Pages 1–6

MalariaWorldHuman malaria, which is caused by infection with Plasmodium, is a serious global public health problem.

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Whole Genome Sequencing of Field Isolates Provides Robust Characterization of Genetic Diversity in Plasmodium vivax

September 11, 2012 - 06:49 -- Kabogo Ndegwa
Author(s): 
Ernest R. Chan, Didier Menard, Peter H. David, Arsène Ratsimbasoa, Saorin Kim, Pheaktra Chim, Catherine Do, Benoit Witkowski, Odile Mercereau-Puijalon, Peter A. Zimmerman, David Serre
Reference: 
PLoS Negl Trop Dis 6(9): e1811

MalariaWorldOur study shows that it is feasible to perform whole genome sequencing of P. vivax field isolates and rigorously characterize the genetic diversity of this parasite.

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A Long Neglected World Malaria Map: Plasmodium vivax Endemicity in 2010

September 11, 2012 - 06:46 -- Kabogo Ndegwa
Author(s): 
Peter W. Gething, Iqbal R. F. Elyazar, Simon I. Hay, et al.
Reference: 
PLoS Negl Trop Dis 6(9): e1814

MalariaWorldThis detailed depiction of spatially varying endemicity is intended to contribute to a much-needed paradigm shift towards geographically stratified and evidence-based planning for P. vivax control and elimination.

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Not Open Access | Plasmodium vivax Pre-Erythrocytic–Stage Antigen Discovery: Exploiting Naturally Acquired Humoral Responses

September 7, 2012 - 04:30 -- Patrick Sampao
Author(s): 
Douglas M. Molina, Olivia C. Finney, Myriam Arevalo-Herrera, Socrates Herrera, Philip L. Felgner, Malcolm J. Gardner, Xiaowu Liang and Ruobing Wang
Reference: 
Am J Trop Med Hyg 2012 87:460-469

MalariaWorldWe screened 60 endemic sera from P. vivax-exposed Fy+ or Fy− donors against a protein microarray containing 91 P. vivax proteins with P. falciparum orthologs that were up-regulated in sporozoites. Antibodies against 10 P. vivax antigens were identified in sera from P. vivax-exposed individuals but not unexposed controls.

Reduced Risk of Plasmodium vivax Malaria in Papua New Guinean Children with Southeast Asian Ovalocytosis in Two Cohorts and a Case-Control Study

September 6, 2012 - 06:40 -- Kabogo Ndegwa
Author(s): 
Anna Rosanas-Urgell, Enmoore Lin, Ivo Mueller, et al.
Reference: 
PLoS Med 9(9): e1001305

MalariaWorldIn three independent studies, we observed strong associations between SAO and protection against P. vivax malaria by a mechanism that is independent of the Duffy antigen. P. vivax malaria may have contributed to shaping the unique host genetic adaptations to malaria in Asian and Oceanic populations.

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Longitudinal in vitro surveillance of Plasmodium falciparum sensitivity to common anti-malarials in Thailand between 1994 and 2010

August 27, 2012 - 07:19 -- Kabogo Ndegwa
Author(s): 
Parker D, Lerdprom R, Srisatjarak W, Yan G, Sattabongkot J, Wood J, Sirichaisinthop J, Cui L
Reference: 
Malaria Journal 2012, 11:290 (21 August 2012)

MalariaWorldParasite sensitivity to anti-malarials in Thailand is highly variable over time and largely mirrors official drug use policy.

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Genetic polymorphisms associated with antimalarial antibody levels in a low and unstable malaria transmission area in southern Sri Lanka

August 22, 2012 - 10:30 -- Kabogo Ndegwa
Author(s): 
Dewasurendra RL, Suriyaphol P, Fernando SD, Carter R, Rockett K, Corran P, Kwiatkowski D, Karunaweera ND
Reference: 
Malaria Journal 2012, 11:281 (20 August 2012)

 

MalariaWorldEvidence is suggestive of an age-acquired immunity in this study population in spite of low malaria transmission levels.

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