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Plasmodium vivax

Open Access | Comparison of the antibody responses to Plasmodium vivax and Plasmodium falciparum antigens in residents of Mandalay, Myanmar

August 11, 2011 - 07:14 -- Kabogo Ndegwa
Author(s): 
Kim T, Kim H, Kim J, Kong Y, Na B, Lin K, Moon S, Kim Y, Kwon M, Sohn Y, Kim H, Lee H
Reference: 
Malaria Journal 2011, 10:228 (6 August 2011)

The positive rates for blood stage antigens of P. falciparum were higher in Group I than in Group II, but the positive rates for antigens of other stages (PfLSA-1 and PfLSA-3) showed opposite results.

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Lack of Molecular Correlates of Plasmodium vivax Ookinete Development

August 4, 2011 - 13:58 -- Patrick Sampao
Author(s): 
Viengngeun Bounkeua, Fengwu Li, Raul Chuquiyauri, Shira R. Abeles, Colleen M. McClean, Victor Neyra, Alejandro Llanos-Cuentas, Pablo P. Yori and Joseph M. Vinetz
Reference: 
Am J Trop Med Hyg 2011 vol. 85 no. 2 207-213

Two methods for production of P. vivax ookinete cultures in vitro, with yields of 106 macrogametocytes, 104 zygotes, and 103 ookinetes, respectively, per 10 mL of P. vivax-infected patient blood with approximately 0.01% parasitemia, were used to study P. vivax sexual stage development.

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In vitro Anti-Malarial Drug Susceptibility of Temperate Plasmodium vivax from Central China

August 4, 2011 - 13:43 -- Patrick Sampao
Author(s): 
Feng Lu,Qi Gao, Kesinee Chotivanich, Hui Xia, Jun Cao, Rachanee Udomsangpetch, Liwang Cui and Jetsumon Sattabongkot
Reference: 
Am J Trop Med Hyg 2011 vol. 85 no. 2 197-201

During 2005–2006, in vitro drug susceptibility was measured for 42 clinical P. vivax isolates by using a schizont maturation inhibition technique.

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Genetic diversity of Plasmodium vivax malaria in China and Myanmar

July 21, 2011 - 14:50 -- Patrick Sampao
Author(s): 
Daibin Zhong, Mariangela Bonizzoni, Guofa Zhou, Guangze Wang, Bin Chen, Anne Vardo-Zalik, Liwang Cui, Guiyun Yan, Bin Zheng
Reference: 
Infection, Genetics and Evolution, Volume 11, Issue 6, August 2011, Pages 1419-1425

Using two polymorphic genetic markers, the merozoite surface protein genes PvMSP-3α and PvMSP-3β, we investigated the genetic diversity of four Southeast Asian P. vivax populations, representing both subtropical and temperate strains with dramatically divergent relapse patterns. PCR amplification of PvMSP-3α and PvMSP-3β genes detected three and four major size polymorphisms among the 235 infections examined, respectively, while restriction analysis detected 15 and 19 alleles, respectively.

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Genetic diversity of Plasmodium vivax Duffy Binding Protein II (PvDBPII) under unstable transmission and low intensity malaria in Sri Lanka

July 21, 2011 - 14:41 -- Patrick Sampao
Author(s): 
Prasad H. Premaratne, B. Ramesh Aravinda, Ananias A. Escalante, Preethi V. Udagama
Reference: 
Infection, Genetics and Evolution, Volume 11, Issue 6, August 2011, Pages 1327-1339

In comparison to the reference Sal-1 strain, among 402 world-wide isolates (302 global and 100 local), 121 aa polymorphisms and 138 haplotypes were recorded of which 3 aa polymorphisms and 21 haplotypes seem to be unique to Sri Lanka.

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Open Access | Plasmodium vivax: comparison of immunogenicity among proteins expressed in the cell-free systems of Escherichia coli and wheat germ by suspension array assays

July 19, 2011 - 08:09 -- Kabogo Ndegwa
Author(s): 
Rui E, Fernandez-Becerra C, Takeo S, Sanz S, Lacerda MV, Tsuboi T, del Portillo HA
Reference: 
Malaria Journal 2011, 10:192 (14 July 2011)

The wheat germ cell-free system offers the possibility of expressing soluble P. vivax proteins in a small-scale for antigen discovery and immuno-epidemiological studies using suspension array technology.

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Conserved sequences of thrombospondin-related adhesive protein gene of Plasmodium vivax in clinical isolates from Korea

July 13, 2011 - 08:04 -- Kabogo Ndegwa
Author(s): 
Myung H. Nam, Jin W. Jang, Hanna Kim, Eun T. Han, Won J. Lee, Seong S. A. An, Ae S. D. Park and Chae S. Lim
Reference: 
Tropical Medicine & International Health, Volume 16, Issue 8, pages 923–928, August 2011

Thrombospondin-related adhesive protein (TRAP) from Plasmodium vivax (P. vivax) became one of the important vaccine candidates for malaria, because P. vivax TRAP (PvTRAP) is responsible for the sporozoite–host interactions.

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Case Report: Malaria Caused by Plasmodium vivax Complicated by Acalculous Cholecystitis

July 7, 2011 - 12:36 -- Patrick Sampao
Author(s): 
Justin M. Curley, Rupal M. Mody and Robert A. Gasser Jr.
Reference: 
Am J Trop Med Hyg 2011 vol. 85 no. 1 42-49

We report the first adult cases of acute acalculous cholecystitis (AAC) exclusively caused by infections with Plasmodium vivax.

Open Access | How Much Remains Undetected? Probability of Molecular Detection of Human Plasmodia in the Field

July 6, 2011 - 08:27 -- Kabogo Ndegwa
Author(s): 
Cristian Koepfli, Sonja Schoepflin, Michael Bretscher, Enmoore Lin, Benson Kiniboro, Peter A. Zimmerman, Peter Siba, Thomas A. Smith, Ivo Mueller, Ingrid Felger
Reference: 
PLoS ONE 6(4): e19010

In malaria endemic areas, most people are simultaneously infected with different parasite clones. Detection of individual clones is hampered when their densities fluctuate around the detection limit and, in case of P. falciparum, by sequestration during part of their life cycle.

Open Access | Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice

July 6, 2011 - 08:20 -- Kabogo Ndegwa
Author(s): 
Michelle N. Wykes, Jason G. Kay, Anthony Manderson, Xue Q. Liu, Darren L. Brown, Derek J. Richard, Jiraprapa Wipasa, Suhua H. Jiang, Malcolm K. Jones, Chris J. Janse, Andrew P. Waters, Susan K. Pierce, Louis H. Miller, Jennifer L. Stow, and Michael F. Good
Reference: 
PNAS July 5, 2011 vol. 108 no. 27 11205-11210

Plasmodium spp. parasites cause malaria in 300 to 500 million individuals each year.

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