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Open Access | Non-variant specific antibody responses to the C-terminal region of merozoite surface protein-1 of Plasmodium falciparum (PfMSP-119) in Iranians exposed to unstable malaria transmission

September 17, 2010 - 13:33 -- Kabogo Ndegwa
Sedigheh Zakeri, Akram A Mehrizi, Samaneh Zoghi, Navid D Djadid
Malaria Journal 2010, 9:257

The present findings demonstrated the presence of non-variant specific antibodies to PfMSP-119 in Iranian falciparum malaria patients. This data suggests that polymorphism in PfMSP-119 is less important and one variant of this antigen, particularly Q/KNG/L, may be sufficient to be included in PfMSP-119-based vaccine.

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