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Plasmodium vivax

Tafenoquine and primaquine do not exhibit clinical neurologic signs associated with central nervous system lesions in the same manner as earlier 8-aminoquinolines

November 7, 2018 - 15:10 -- Open Access
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Author(s): 
Jonathan Berman, Tracey Brown, Geoffrey Dow and Stephen Toovey
Reference: 
Malaria Journal 2018 17:407, 6 November 2018

Extrapolation of data from Rhesus monkeys to humans, and the available clinical data, suggest that tafenoquine also does not exhibit pamaquine, pentaquine or plasmocid-like clinical neurologic signs in humans.

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Adaptive Evolution of RH5 in Ape Plasmodium species of the Laverania Subgenus

March 13, 2018 - 13:37 -- Open Access
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Author(s): 
Lindsey J. Plenderleith, Weimin Liu, Paul M. Sharp, et al.
Reference: 
mBio January/February 2018 9:e02237-17

Plasmodium falciparum, the major cause of malaria morbidity and mortality in humans, has been shown to have emerged after cross-species transmission of one of six host-specific parasites (subgenus Laverania) infecting wild chimpanzees (Pan troglodytes) and western gorillas (Gorilla gorilla).

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G6PD deficiency alleles in a malaria-endemic region in the Western Brazilian Amazon

June 15, 2017 - 15:43 -- Open Access
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Author(s): 
Jamille G. Dombrowski, Rodrigo M. Souza, Claudio R. F. Marinho, et al.
Reference: 
Malaria Journal 2017 16:253, 15 June 2017

The data indicates that ~1/23 males from the Alto do Juruá could be G6PD deficient and at risk of haemolytic anaemia if treated with primaquine.

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Asymptomatic and sub-microscopic malaria infection in Kayah State, eastern Myanmar

April 11, 2017 - 15:34 -- Open Access
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Author(s): 
Myo Thiha Zaw, Myo Thant, Jetsumon Sattabongkot, et al.
Reference: 
Malaria Journal 2017 16:138, 4 April 2017

A combination of RDT, light microscopy and PCR diagnostics were used to identify asymptomatic malaria infection, providing additional information on asymptomatic cases in addition to the routine statistics on symptomatic cases, so as to determine the true burden of disease in the area.

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Malaria elimination challenges in Mesoamerica: evidence of submicroscopic malaria reservoirs in Guatemala

September 3, 2016 - 16:33 -- Open Access
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Author(s): 
Shirley Evelyn Lennon, Adolfo Miranda, Juliana Henao, Andres F. Vallejo, Julianh Perez, Alvaro Alvarez, Myriam Arévalo-Herrera and Sócrates Herrera
Reference: 
Malaria Journal 2016 15:441, 30 August 2016

This study found a considerable number of asymptomatic P. vivax infections that were mostly submicroscopic, of which, approximately one-quarter harboured mature gametocytes.

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Diagnosis of an imported Plasmodium ovale wallikeri infection in Malaysia

January 12, 2016 - 16:50 -- Open Access
Author(s): 
Jonathan Liew, Rohela Mahmud, Lian Tan, Yee Lau
Reference: 
Malaria Journal 2016, 15:8 (6 January 2016)

Plasmodium ovale is rare and not exactly known to be autochthonous in Malaysia.

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Column: Sleepless in the liver: would revisiting the past give any directions on how to deal with hypnozoite carriers of P. vivax?

February 6, 2014 - 20:51 -- Bart G.J. Knols
Many of the recent strategies to improve malaria control have been focusing on improving the detection of very low parasitaemias to identify asymptomatic carriers of Plasmodium sp. to reduce the infective reservoir. Although these strategies are extremely rational and sensible to tackle most of malaria infections, they will probably not be sufficient to achieve elimination for parasites that present relapses, as is the case for Plasmodium vivax. The need to look for new and sophisticated methods has been exhaustively stressed by researchers, however, at this time, revisiting a simple and efficient strategy successfully employed in the past could prove to be a path to be followed...

Not Open Access | Reticulocytes from cryopreserved erythroblasts support Plasmodium vivax infection in vitro

December 17, 2013 - 18:54 -- NOT Open Access
Author(s): 
Tetsuya Furuya, Juliana M. Sá, Chetan E. Chitnis, Thomas E. Wellems, Timothy T. Stedman
Reference: 
Parasitology International, Volume 63, Issue 2, April 2014, Pages 278-284

Here, we report an improved method of hematopoietic stem cell culture for P. vivax infection, which requires less time and produces higher or equivalent percentage of reticulocytes than previously reported systems.

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Genetic diversity of Plasmodium vivax and Plasmodium falciparum in Honduras

November 27, 2012 - 15:51 -- Open Access
Author(s): 
Lopez AC, Ortiz A, Coello J, Sosa-Ochoa W, Torres RE, Banegas EI, Jovel I, Fontecha GA
Reference: 
Malaria Journal 2012, 11:391 (26 November 2012)
MalariaWorld

To date, this is the most complete report on molecular characterization of P. vivax and P. falciparum field isolates in Honduras with regards to genetic diversity. These results indicate that P. vivax and P. falciparum parasite populations are highly diverse in Honduras despite the low level of transmission.

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Renal cortical necrosis and acute kidney injury associated with Plasmodium vivax: a neglected human malaria parasite

November 11, 2012 - 11:24 -- Open Access
Author(s): 
Vivek B. Kute, Aruna V. Vanikar, Pramod P. Ghuge, Jitendra G. Goswami, Mohan P. Patel, Himanshu V. Patel, Manoj R. Gumber, Pankaj R. Shah & Hargovind L. Trived
Reference: 
Parasitology Research, Volume 111, Number 5 (2012), 2213-2216
MalariaWorld

Plasmodium vivax is causing increasingly more cases of severe malaria worldwide.

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