IPTc is a safe method of malaria control that has the potential to avert a significant proportion of clinical malaria episodes in areas with markedly seasonal malaria transmission and also appears to have a substantial protective effect against all-cause mortality.
IPTc is a safe method of malaria control that has the potential to avert a significant proportion of clinical malaria episodes in areas with markedly seasonal malaria transmission and also appears to have a substantial protective effect against all-cause mortality.
IPT of malaria provides substantial protection against malaria in children who sleep under an ITN.
Monitoring, evaluation, and surveillance measure how well public health programs operate over time and achieve their goals.
Plasmodium falciparum parasitaemia in asymptomatic Fulani is more common in individuals with lactase non-persistence genotypes, but this difference is not statistically significant.
Cytoadherence properties of two categories of Plasmodium falciparum isolates from Sri Lanka were assessed using CHO-CD36 and CHO-ICAM-1 stable transfected cell lines, and the association with the clinical disease in patients, from whom the parasites were obtained was also analyzed.
Plasmodium ovale malaria is currently a problem to diagnose in travellers, notably in French soldiers returning from the Ivory Coast.
PCR has proven to be one of the most specific and sensitive diagnostic methods, particularly for malaria cases with low parasitaemia.
Congenital and neonatal malaria are rare in this malaria endemic region. Performing a blood slide for malaria parasites among sick neonates in malaria endemic regions is advisable.
To investigate the effect of caspase-12 deficiency on IFN-γ-independent control of blood-stage malaria, we compared lethal Plasmodium yoelii 17XL infection in wild-type C57BL/6J and caspase-12−/− mice. Infected caspase-12−/− mice exhibited higher parasitaemia than WT mice on days 8 and 9 post-inoculation, but all WT and caspase-12−/− mice succumbed by day 10. In addition, infected caspase-12−/− mice had significantly elevated levels of IFN-γ, TNF, IL-18, and IL-10 in sera compared to infected WT mice.
