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Downstream effects of haemoglobinase inhibition in Plasmodium falciparum-infected erythrocytes

July 19, 2010 - 10:04 -- Patrick Sampao
Julie A. Naughton, Sima Nasizadeh, Angus Bell
Molecular and Biochemical Parasitology, Volume 173, Issue 2, October 2010, Pages 81-87

In this study we examined the downstream effects of reduced haemoglobin digestion on osmoprotection and nutrition. We found that inhibitors of haemoglobinases (plasmepsins, falcipains and aminopeptidases) did not cause premature haemolysis.

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