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Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines.

November 18, 2009 - 12:56 -- Kabogo Ndegwa
Martin Michaelis, Malte C. Kleinschmidt, Susanne Barth, Florian Rothweiler, Janina Geiler, Rainer Breitling, Bernd Mayer, Hedwig Deubzer, Olaf Witt, Jörg Kreuter, Hans Wilhelm Doerr, Jaroslav Cinatl, Jindrich Cinatl Jr.
Biochemical Pharmacology, Volume 79, Issue 2, 15 January 2010, Pages 130-136, doi:10.1016/j.bcp.2009.08.013

Artemisinin derivatives are well-tolerated anti-malaria drugs that also exert anti-cancer activity. Here, we investigated artemisinin and its derivatives dihydroartemisinin and artesunate in a panel of chemosensitive and chemoresistant human neuroblastoma cells as well as in primary neuroblastoma cultures.

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