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Cu/Zn Superoxide Dismutase

Inflamation: Heme Impairs Prostaglandin E2 and TGF-β Production by Human Mononuclear Cells via Cu/Zn Superoxide Dismutase: Insight into the Pathogenesis of Severe Malaria

July 6, 2010 - 06:38 -- Kabogo Ndegwa
Author(s): 
Bruno B. Andrade, Théo Araújo-Santos, Nívea F. Luz, Ricardo Khouri, Marcelo T. Bozza, Luís M. A. Camargo, Aldina Barral, Valéria M. Borges, and Manoel Barral-Netto
Reference: 
The Journal of Immunology, 2010, 185, 1196 -1204

In many hemolytic disorders, such as malaria, the release of free heme has been involved in the triggering of oxidative stress and tissue damage. Patients presenting with severe forms of malaria commonly have impaired regulatory responses.

Medical Treatment: 

Heme Impairs Prostaglandin E2 and TGF-β Production by Human Mononuclear Cells via Cu/Zn Superoxide Dismutase: Insight into the Pathogenesis of Severe Malaria

June 22, 2010 - 09:47 -- Kabogo Ndegwa
Author(s): 
Bruno B. Andrade, Théo Araújo-Santos, Nívea F. Luz, Ricardo Khouri, Marcelo T. Bozza, Luís M. A. Camargo, Aldina Barral, Valéria M. Borges, and Manoel Barral-Netto
Reference: 
J Immunol published 18 June 2010, 10.4049/jimmunol.0904179

In many hemolytic disorders, such as malaria, the release of free heme has been involved in the triggering of oxidative stress and tissue damage. Patients presenting with severe forms of malaria commonly have impaired regulatory responses.

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