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Guest editorial: “End Malaria for Good”- a few key messages based on the Cambodian experience

June 23, 2016 - 07:27 -- Bart G.J. Knols
The editorial below was contributed by Sara E Canavati and Jack S Richards. Contact details below.
 
World Malaria Day (WMD) is an international observance established in 2007 and commemorated every year on 25 April to recognize global efforts to control malaria. The theme for 2016 was “End Malaria For Good”, which focused on malaria elimination. Following the great progress made under the Millennium Development Goals, it is important to continue building on this success as we transition into the Sustainable Development Goals [1] and the recently launched Global Technical Strategy for Malaria (GTS) [2]. The aim of the piece is to briefly reflect on WMD 2016 and consider a few key operational issues on malaria elimination that may lie ahead for the coming year.

NOT Open Access | Malaria in pregnancy shapes the development of foetal and infant immunity

March 6, 2019 - 13:22 -- NOT Open Access
Author(s): 
Whitney E. Harrington, Abel Kakuru, Prasanna Jagannathan
Reference: 
Parasitic Infection and Maternal Immunity Volume41, Issue3 March 2019 e12573

Malaria, particularly Plasmodium falciparum, continues to disproportionately affect pregnant women.

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Origins and spread of novel genetic variants of sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates in Indonesia

January 2, 2019 - 15:09 -- Open Access
Author(s): 
Sukmawati Basuki, Fitriah, Haruki Uemura, et al.
Reference: 
Malaria Journal 2018 17:475, 17 December 2018

Analysis of the prevalence and pfdhfr/pfdhps combined genotypes of K540T or I588F mutations suggested that K540T might be origin in Kalimantan Island and I588F in Sumbawa Island and then these were spread to other areas along with people movement.

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How can we promote more active dialogue on malaria?

September 10, 2018 - 13:27 -- William Jobin

Dear colleagues,
As you probably do, I eagerly check MalariaWorld almost every day, and when I have something to contribute, post a blog or comment. But I am disappointed by the lack of responses to my contributions, or to those from all of you. How can we improve this?
Since almost 10,000 people are connected thru MalariaWorld, we might make real progress if we can all contribute. I want to end malaria sooner, not later. Do you agree?
Bill Jobin

Not Open Access | Selection of Plasmodium falciparum cytochrome B mutants by putative PfNDH2 inhibitors

June 15, 2018 - 16:24 -- NOT Open Access
Author(s): 
Kristin D. Lane, Jianbing Mu, Jinghua Lu, Sean T. Windle, Anna Liu, Peter D. Sun, and Thomas E. Wellems
Reference: 
PNAS June 12, 2018. 115 (24) 6285-6290

Malaria control is threatened by a limited pipeline of effective pharmaceuticals against drug-resistant strains of Plasmodium falciparum.

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Disrupting CD147-RAP2 interaction abrogates erythrocyte invasion by Plasmodium falciparum

March 13, 2018 - 13:39 -- Open Access
Author(s): 
Meng-Yao Zhang, Yang Zhang, Zhi-Nan Chen, et al.
Reference: 
Blood 2018, Volume: 131 Issue: 10 Pages: 1111-1121

Effective vaccines against malaria caused by Plasmodium falciparum are still lacking, and the molecular mechanism of the host-parasite interaction is not fully understood.

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Identification and characterization of areas of high and low risk for asymptomatic malaria infections at sub-village level in Ratanakiri, Cambodia

January 16, 2018 - 16:08 -- Open Access
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Author(s): 
Lies Durnez, Myrthe Pareyn, Vanna Mean, Saorin Kim, Nimol Khim, Didier Menard, Marc Coosemans, Tho Sochantha and Vincent Sluydts
Reference: 
Malaria Journal 2018 17:27, 15 January 2018

Clusters of malaria carriers were malaria species specific and often located remotely, outside village centres.

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