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Africa

Open Access | Comparative analyses reveal discrepancies among results of commonly used methods for Anopheles gambiae molecular form identification

August 4, 2011 - 11:59 -- Kabogo Ndegwa
Author(s): 
Santolamazza F, Caputo B, Calzetta M, Vicente JL, Mancini E, Petrarca V, Pinto J, della Torre A
Reference: 
Malaria Journal 2011, 10:215 (2 August 2011)

Anopheles gambiae M and S molecular forms, the major malaria vectors in the Afro-tropical region, are ongoing a process of ecological diversification and adaptive lineage splitting, which is affecting malaria transmission and vector control strategies in West Africa.

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SNP genotyping defines complex gene-flow boundaries among african malaria vector mosquitoes

October 27, 2010 - 13:09 -- Kabogo Ndegwa
Author(s): 
DE Neafsey, MK Lawniczak,MA Muskavitch, et al.
Reference: 
Science 22 October 2010: Vol. 330. no. 6003, pp. 514 – 517

Mosquitoes in the Anopheles gambiae complex show rapid ecological and behavioral diversification, traits that promote malaria transmission and complicate vector control efforts.

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Open Access | Further Evidence Supporting a Role for Gs Signal Transduction in Severe Malaria Pathogenesis

April 8, 2010 - 12:56 -- Kabogo Ndegwa
Author(s): 
Sarah Auburn, Andrew E. Fry, Taane G. Clark, Susana Campino, Mahamadou Diakite, Angela Green, Anna Richardson, Muminatou Jallow, Fatou Sisay-Joof, Margaret Pinder, Malcolm E. Molyneux, Terrie E. Taylor, Kasturi Haldar, Kirk A. Rockett, Dominic P. Kwiatkowski
Reference: 
PLoS ONE 5(4): e10017.

Having previously demonstrated a role for the G-alpha-s gene, GNAS, in severe malaria disease, we sought to identify other important components of the Gs pathway.

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