Cedrol an oviposition attractant for African malaria vectors is produced by two fungi species isolated from grass rhizomes collected from a natural mosquito breeding site.
These studies demonstrate exacerbated neuroinflammation concurrent with development of behavioural symptoms in P. chabaudi infection of IL-10−/− animals.
This means that calculations of the reduction in R 0 that interventions can achieve (the effect size) have a useful and straightforward interpretation, whereas if the theoretical possibility of a bistable equilibrium were the real behaviour, then such effect size calculations would not have a clear interpretation.
Aside from antimalarials, there is currently no treatment for cerebral malaria, a fulminant neurological complication of P. falciparum infection that is a leading cause of death in African children.
LT are a crude tool at best, but are relatively easy to deploy on a large scale.
Blood donations infected with Plasmodium can transmit malaria to donation recipients.
Travel to Mexico represents a large percentage of US donors deferred for malaria risk; however, these donors primarily visit no- or very-low-risk areas.
Jim Webb's forthcoming book on the history of the fight against malaria in Africa is a plea for all of us..... (for me that includes WHO and USPMI folks)..... to learn from history, especially the history of these clever mosquitoes who quickly learn to overcome any synthetic biocide produced by the chemical industry. He cites the experience in Turkey, Pakistan and Sudan where the malaria programs went through 8 major classes of biocides after DDT lost its effect..........
These findings are supported by a report from Madagascar (where the human population is composed of a mixture of Duffy-positive and Duffy-negative persons), in which 42 (8.8%) of 476 Duffy-negative persons who had symptoms of malaria were reported to be positive for P. vivax by both microscopy and PCR.
Organisation: AIGHD & AMC
Date: June 19th, 2012
Time: 12.30-17.00 hrs
Location: Academic Medical Center (AMC) Lecture Hall 5, Meibergdreef 9, 1105 AZ, Amsterdam