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China

Genetic polymorphism of merozoite surface proteins 1 and 2 of Plasmodium falciparum in the China-Myanmar border region

December 2, 2019 - 17:54 -- Open Access
Author(s): 
Zhang CL, Zhou HN, Liu Q, Yang YM
Reference: 
Malar J. 2019 Nov 19;18(1):367

Malaria is a major public health problem in the China-Myanmar border region. The genetic structure of malaria parasite may affect its transmission model and control strategies. The present study was to analyse genetic diversity of Plasmodium falciparum by merozoite surface proteins 1 and 2 (MSP1 and MSP2) and to determine the multiplicity of infection in clinical isolates in the China-Myanmar border region.

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Analysis on external competency assessment for malaria microscopists in China

November 19, 2019 - 06:14 -- Open Access
Author(s): 
Mei Li, Hejun Zhou, He Yan, Jianhai Yin, Xinyu Feng, Zhigui Xia and Shuisen Zhou
Reference: 
Malaria Journal 2019 18:366, 14 November 2019

In order to meet the requirement of malaria elimination (ME), three courses of the External Competency Assessment of Malaria Microscopists (ECAMM) were conducted during 2017–2018 in China by facilitators designated by the World Health Organization (WHO-ECAMM). A training course with a model copied from the WHO-ECAMM course was also held a week ahead of ECAMM in March 2018. Thirty-six participants completed these courses and obtained different results.

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K13-propeller gene polymorphisms of Plasmodium falciparum and the therapeutic effect of artesunate among migrant workers returning to Guangxi, China (2014–2017)

October 22, 2019 - 16:36 -- Open Access
Author(s): 
Jun Li, Yunliang Shi, Jian Qin, et al.
Reference: 
Malaria Journal 2019 18:349, 16 October 2019

The resistance of Plasmodium falciparum to artemisinin has been identified in Asia and some parts of Africa. The drug resistance of P. falciparum will be an obstacle to the successful elimination of malaria by 2025. Whole-genome sequencing of the artemisinin-resistant parasite line revealed mutations on the k13 gene associated with drug resistance in P. falciparum. To understand the artemisinin resistance of the imported P. falciparum cases from Africa, the mutations in the k13 gene in parasites from imported malaria cases in Guangxi Province were detected and the treatment efficiency of artesunate monotherapy was observed.

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Monitoring and evaluation of intervals from onset of fever to diagnosis before “1-3-7” approach in malaria elimination: a retrospective study in Shanxi Province, China from 2013 to 2018

July 15, 2019 - 15:14 -- Open Access
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Author(s): 
Ting Wang, Shui-Sen Zhou, Jun Feng, Myo Minn Oo, Jing Chen, Chang-Fu Yan, Yi Zhang and Ping Tie
Reference: 
Malaria Journal 2019 18:235, 12 July 2019

China’s 1-3-7 approach was extensively implemented to monitor the timeframe of case reporting, case investigation and foci response in the malaria elimination. However, activities before diagnosis and reporting (before ‘1’) would counteract the efficiency of 1-3-7 approach but few data have evaluated this issue. This study aims to evaluate the timelines between onset of fever and diagnosis at healthcare facilities in Shanxi Province.

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The polymorphism and geographical distribution of knockdown resistance of adult Anopheles sinensis populations in eastern China

May 13, 2019 - 12:14 -- Open Access
Author(s): 
Wei-Long Tan, Chun-Xiao Li, Tong-Yan Zhao, et al.
Reference: 
Malaria Journal 2019 18:164, 7 May 2019

Anopheles sinensis is one of the major malaria vectors in China and other southeast Asian countries, including Vietnam, Cambodia, Thailand. Vector control is considered to be the critical measure for malaria control, while the increasing prevalence of insecticide resistance caused by long-term use of insecticides, especially pyrethroids, is threatening the successful control of An. sinensis. In order to understand the underlying resistance mechanisms involved and molecular basis, the principal malaria vector, An. sinensis from Jiangsu and Anhui provinces, Southeast China, was investigated.

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Changing epidemiology and challenges of malaria in China towards elimination

April 2, 2019 - 11:15 -- Open Access
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Author(s): 
Shengjie Lai, Junling Sun, Nick W. Ruktanonchai, Sheng Zhou, Jianxing Yu, Isobel Routledge, Liping Wang, Yaming Zheng, Andrew J. Tatem and Zhongjie Li
Reference: 
Malaria Journal 2019 18:107, 29 March 2019

China is on the verge of malaria elimination, but the residual transmission in border regions and the threats of importation from Africa and Southeast Asia are the key challenges to achieve and maintain malaria elimination.

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Genetic association between the Pfk13 gene mutation and artemisinin resistance phenotype in Plasmodium falciparum isolates from Yunnan Province, China

January 2, 2019 - 15:20 -- Open Access
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Author(s): 
Ying Dong, Jian Wang, Aiming Sun, Yan Deng, Mengni Chen, Yanchun Xu and Jingpo Xue
Reference: 
Malaria Journal 2018 17:478, 18 December 2018

Although the Plasmodium isolates from Yunnan Province and those from Myanmar were collected from different sites, they still belong to the same geographical population.

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An odorant receptor from Anopheles sinensis in China is sensitive to oviposition attractants

October 16, 2018 - 14:10 -- Open Access
Author(s): 
Hongmei Liu, Luhong Liu, Peng Cheng, Xiaodan Huang and Maoqing Gong
Reference: 
Malaria Journal 2018 17:348, 5 October 2018

AsinOrco was characterized as a new member of the Orco ortholog subfamily.

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Ready for malaria elimination: zero indigenous case reported in the People’s Republic of China

August 29, 2018 - 15:35 -- Open Access
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Author(s): 
Jun Feng, Li Zhang, Fang Huang, Jian-Hai Yin, Hong Tu, Zhi-Gui Xia, Shui-Sen Zhou, Ning Xiao and Xiao-Nong Zhou
Reference: 
Malaria Journal 2018 17:315, 29 August 2018

Malaria elimination in China is a country-led and country-owned endeavour.

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Malaria training for community health workers in the setting of elimination: a qualitative study from China

February 27, 2018 - 15:43 -- Open Access
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Author(s): 
Guangyu Lu, Yaobao Liu, Jinsong Wang, Xiangming Li, Xing Liu, Claudia Beiersmann, Yu Feng, Jun Cao and Olaf Müller
Reference: 
Malaria Journal 2018 17:95, 23 February 2018

There is need to guarantee an ongoing good training of health workers in China on malaria aspects until the year 2020 and probably beyond.

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