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Thailand

Molecular detection of drug resistant malaria in Southern Thailand

August 19, 2019 - 17:40 -- Open Access
Author(s): 
Chaturong Noisang, Christiane Prosser, Wieland Meyer, Waenurama Chemoh, John Ellis, Nongyao Sawangjaroen and Rogan Lee
Reference: 
Malaria Journal 2019 18:275, 15 August 2019

Drug resistance within the major malaria parasites Plasmodium vivax and Plasmodium falciparum threatens malaria control and elimination in Southeast Asia. Plasmodium vivax first-line treatment drug is chloroquine together with primaquine, and the first-line treatment for P. falciparum malaria is artemisinin in combination with a partner drug. Plasmodium vivax and P. falciparum parasites resistant to their respective first-line therapies are now found within Southeast Asia. The resistance perimeters may include high transmission regions of Southern Thailand which are underrepresented in surveillance efforts.

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Spatiotemporal epidemiology, environmental correlates, and demography of malaria in Tak Province, Thailand (2012–2015)

July 21, 2019 - 21:36 -- Open Access
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Author(s): 
Chris Erwin G. Mercado, Saranath Lawpoolsri, Richard J. Maude, et al.
Reference: 
Malaria Journal 2019 18:240, 16 July 2019

Tak Province, at the Thai–Myanmar border, is one of three high malaria incidence areas in Thailand. This study aimed to describe and identify possible factors driving the spatiotemporal trends of disease incidence from 2012 to 2015.

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NOT Open Access | Evaluation of Plasmodium vivax isolates in Thailand using polymorphic markers Plasmodium merozoite surface protein (PvMSP) 1 and PvMSP3

November 21, 2018 - 15:29 -- NOT Open Access
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Author(s): 
Nutnicha Suphakhonchuwong, Wanna Chaijaroenkul, Kanchana Rungsihirunrat, Kesara Na-Bangchang & Jiraporn Kuesap
Reference: 
Parasitology Research December 2018, Volume 117, Issue 12, pp 3965–3978

Malaria is a significant public health problem in several tropical countries including Thailand.

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Bayesian spatiotemporal analysis of malaria infection along an international border: Hlaingbwe Township in Myanmar and Tha-Song-Yang District in Thailand

November 20, 2018 - 14:53 -- Open Access
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Author(s): 
Aung Minn Thway, Chawarat Rotejanaprasert, Jetsumon Sattabongkot, Siam Lawawirojwong, Aung Thi, Tin Maung Hlaing, Thiha Myint Soe and Jaranit Kaewkungwal
Reference: 
Malaria Journal 2018 17:428, 16 November 2018

The analytic model developed in this study could be used for assessing the probability of hotspot cluster, which would be beneficial for setting priorities and timely preventive actions in such hotspot cluster areas.

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Population pharmacokinetics of mefloquine given as a 3-day artesunate–mefloquine in patients with acute uncomplicated Plasmodium falciparum malaria in a multidrug-resistant area along the Thai–Myanmar border

September 4, 2018 - 16:09 -- Open Access
Author(s): 
Richard M. Hoglund, Ronnatrai Ruengweerayut and Kesara Na-Bangchang
Reference: 
Malaria Journal 2018 17:322, 3 September 2018

The study successfully describes the pharmacokinetics of mefloquine following a 2-day treatment of mefloquine as a part of a 3-day artesunate–mefloquine in patients with uncomplicated falciparum malaria from Thailand.

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NOT Open Access | Discriminating lethal concentrations for pyrethroid compounds used in susceptibility monitoring of Anopheles epiroticus, a malaria vector in Thailand

July 14, 2018 - 15:25 -- NOT Open Access
Author(s): 
Watcharin Phoomkhong, Michael J. Bangs, Theeraphap Chareonviriyaphap
Reference: 
Acta Tropica Volume 185, September 2018, Pages 255-260

Anopheles epiroticus is a malaria vector in Thailand found primarily along coastal areas with brackish water habitats.

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Substantial population structure of Plasmodium vivax in Thailand facilitates identification of the sources of residual transmission

October 30, 2017 - 06:13 -- Open Access
Author(s): 
Veerayuth Kittichai, Cristian Koepfli, Wang Nguitragool, Jetsumon Sattabongkot, Liwang Cui
Reference: 
PLoS Negl Trop Dis11(10): e0005930

Significant parasite genetic differentiation between provinces shows successful interruption of parasite spread within Thailand, but high diversity along international borders implies a substantial parasite population size in these regions.

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Plasmodium vivax rhomboid-like protease 1 gene diversity in Thailand

September 11, 2017 - 15:28 -- Open Access
Author(s): 
Touchchapol Mataradchakul, Chairat Uthaipibull, Francois Nosten, Joel Vega-Rodriguez, Marcelo Jacobs-Lorena, Usa Lek-Uthai
Reference: 
Experimental Parasitology Volume 181, October 2017, Pages 1-6

The relatively high degree of Pvrom1 polymorphism suggests that the protein is important for parasite survival in face of changes in both insect vector and human populations.

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Status of insecticide resistance in Anopheles mosquitoes in Ubon Ratchathani province, Northeastern Thailand

July 26, 2017 - 15:49 -- Open Access
Author(s): 
Anchana Sumarnrote, Hans J. Overgaard, Nattapol Marasri, Bénédicte Fustec, Kanutcharee Thanispong, Theeraphap Chareonviriyaphap and Vincent Corbel
Reference: 
Malaria Journal 2017 16:299, 25 July 2017

This study shows that insecticide resistance is present in potential malaria vectors in northeastern Thailand.

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Imported Plasmodium falciparum and locally transmitted Plasmodium vivax: cross-border malaria transmission scenario in northwestern Thailand

June 27, 2017 - 17:55 -- Open Access
Author(s): 
Patchara Sriwichai, Stephan Karl, Yudthana Samung, Kirakorn Kiattibutr, Jeeraphat Sirichaisinthop, Ivo Mueller, Liwang Cui and Jetsumon Sattabongkot
Reference: 
Malaria Journal 2017 16:258, 21 June 2017

On the Thai–Myanmar border, P. falciparum infections occur mostly in the recent migrant population with a seasonality reflecting that of agricultural activity, rather than that of the local mosquito population.

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