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Peru

Open Access | A Large Proportion of P. falciparum Isolates in the Amazon Region of Peru Lack pfhrp2 and pfhrp3: Implications for Malaria Rapid Diagnostic Tests

January 29, 2010 - 14:01 -- Ingeborg van Schayk
Author(s): 
Gamboa D, Ho M-F, Bendezu J, Torres K, Chiodini PL, et al.
Reference: 
PLoS ONE 5(1): e8091

RDTs detecting parasite LDH or aldolase and quality microscopy should be use for malaria diagnosis in this region. There is an urgent need for investigation of the abundance and geographic distribution of these parasites in Peru and neighbouring countries.

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Open Access | The Plasmodium falciparum merozoite surface protein-1 19kD antibody response in the Peruvian Amazon predominantly targets the non-allele specific, shared sites of this antigen

January 7, 2010 - 13:45 -- Ingeborg van Schayk
Author(s): 
Patrick L Sutton, Eva H Clark, Claudia Silva, OraLee H Branch
Reference: 
Malaria Journal 2010, 9:3 (4 January 2010)

Here, the potential for allele-specific polymorphisms in this population is investigated, and the allele-specificity of antibody responses to PfMSP119kD are determined.

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Plasmodium falciparum and Plasmodium vivax Infections in the Peruvian Amazon: Propagation of Complex, Multiple Allele-Type Infections without Super-Infection

December 18, 2009 - 15:54 -- Ingeborg van Schayk
Author(s): 
Patrick L. Sutton, Victor Neyra, Jean N. Hernandez, AND OraLee H. Branch
Reference: 
Am J Trop Med Hyg 2009;81 950-960

The results suggest propagation of mixed infections by multiple inocula, not super-infection, implying decade-long opportunity for outcrossing in these mixed infections.

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