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Indonesia

Open Access | Efficacy and safety of artemisinin-naphthoquine versus dihydroartemisinin-piperaquine in adult patients with uncomplicated malaria: a multi-centre study in Indonesia

May 9, 2012 - 10:53 -- Kabogo Ndegwa
Author(s): 
Tjitra E, Hasugian AR, Siswantoro H, Prasetyorini B, Ekowatiningsih R, Yusnita EA, Purnamasari T, Driyah S, Salwati E, Nurhayati N, Yuwarni E, Yanuar L, Labora J, Wijayanto B, Amansyah F, Dedang TA, Purnama A, Trihono T
Reference: 
Malaria Journal 2012, 11:153 (3 May 2012)

MalariaWorldAN and DHP are confirmed very effective, safe and tolerate for treatment of any malaria. Both drugs are promising for multiple first-line therapy policies in Indonesia.

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Open Access | Existence of the Rdl mutant alleles among the Anopheles malaria vector in Indonesia

February 28, 2012 - 10:16 -- Patrick Sampao
Author(s): 
Asih PB, Syahrani L, Rozi IE, Pratama NR, Marantina SS, Arsyad DS, Mangunwardoyo W, Hawley W, Laihad F, Shinta S, Sukowati S, Lobo NF, Syafruddin D
Reference: 
Malaria Journal 2012, 11:57 (25 February 2012)

MalariaWorldNonetheless, the finding suggests that integrated pest management is warranted in malaria-endemic areas where insecticides are widely used for other purposes.

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Etiology of Acute, Non-Malaria, Febrile Illnesses in Jayapura, Northeastern Papua, Indonesia

January 10, 2012 - 15:03 -- Patrick Sampao
Author(s): 
Narain H. Punjabi, Walter R. J. Taylor, Thomas L. Richie, et al.
Reference: 
Am J Trop Med Hyg 2012 86:46-51

MalariaWorldWe conducted a prospective, inpatient fever study in malaria-endemic Papua, Indonesia to determine non-malaria fever etiologies.

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Open Access | Coma Associated with Microscopy-Diagnosed Plasmodium vivax: A Prospective Study in Papua, Indonesia

June 9, 2011 - 07:35 -- Kabogo Ndegwa
Author(s): 
Daniel A. Lampah, Tsin W. Yeo, Setiawan O. Hardianto, Emiliana Tjitra, Enny Kenangalem, Paulus Sugiarto, Ric N. Price, Nicholas M. Anstey
Reference: 
PLoS Negl Trop Dis 5(6): e1032

P. vivax-associated coma is rare, occurring 23 times less frequently than that seen with falciparum malaria, and is associated with a high proportion of non-malarial causes and mixed infections using PCR.

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Chapter 2-Malaria Distribution, Prevalence, Drug Resistance and Control in Indonesia

February 9, 2011 - 08:49 -- Kabogo Ndegwa
Author(s): 
Iqbal R.F. Elyazar, Simon I. Hay, J. Kevin Baird
Reference: 
Advances in Parasitology, Volume 74, 2011, Pages 41-175

Approximately 230 million people live in Indonesia. The country is also home to over 20 anopheline vectors of malaria which transmit all four of the species of Plasmodium that routinely infect humans.

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Open Access | Detection of 1014F kdr mutation in four major Anopheline malaria vectors in Indonesia

November 16, 2010 - 12:28 -- Kabogo Ndegwa
Author(s): 
Din Syafruddin, Anggi PN Hidayati, Puji BS Asih, Wiiliam A Hawley, Supratman Sukowati, Neil F Lobo
Reference: 
Malaria Journal 2010, 9:315 (8 November 2010)

The finding documents the presence of this mutant allele in Indonesia, and implies that selection pressure on the Anopheles population in this area has occurred. Further studies to determine the impact of the resistance allele on the efficacy of pyrethroids in control programmes are needed.

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Open Access | Relationships between anopheline mosquitoes and topography in West Timor and Java, Indonesia

August 31, 2010 - 13:15 -- Kabogo Ndegwa
Author(s): 
Ndoen E, Wild C, Dale P, Sipe N, Dale M
Reference: 
Malaria Journal 2010, 9:242 (26 August 2010)

Information on significant malaria vectors associated with specific topography is useful for planning the mosquito control aspect of malaria management.

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Manadoperoxides A-D from the Indonesian Sponge Plakortis cfr. simplex. Further Insights on the Structure-Activity Relationships of Simple 1,2-Dioxane Antimalarials

June 9, 2010 - 08:01 -- Kabogo Ndegwa
Author(s): 
C Fattorusso, M Persico, B Calcinai, C Cerrano, S Parapini, D Taramelli, E Novellino, A Romano, F Scala, E Fattorusso, O Taglialatela-Scafati
Reference: 
J. Nat. Prod. June 3, 2010

The new endoperoxyketal polyketides manadoperoxides A−D (2−5) have been isolated from the Indonesian sponge Plakortis cfr. simplex and their stereostructures established by means of spectroscopic data and semisynthetic transformations.

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Open Access | Study Protocol: Does treatment of intestinal helminth infections influence malaria? Background and methodology of a longitudinal study of clinical, parasitological and immunological parameters in Nangapanda, Flores, Indonesia

March 31, 2010 - 15:03 -- Kabogo Ndegwa
Author(s): 
Wiria AE, Prasetyani MA, Supali T, et al.
Reference: 
BMC Infectious Diseases 2010, Volume 10, Issue 77 (25 March 2010)

The study will provide data on the effect of helminth infections on malaria. It will also give information on anthelminthic treatment efficacy and effectiveness and could help develop
evidence-based policymaking.

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Open Access | Evaluation of chloroquine therapy for vivax and falciparum malaria in southern Sumatra, western Indonesia

February 17, 2010 - 20:26 -- Ingeborg van Schayk
Author(s): 
Inge Sutanto, Dedeh Endawati, Liem Hui Ling, Ferdinand Laihad, Rianto Setiabudy, J Kevin Baird
Reference: 
Malaria Journal 2010, 9:52 (12 February 2010)

Clinical trial of the use of chloroquine for monoinfections of P.falciparum and P. vivax. Although a small study and almost 7 years old, the data provide clear evidence of high grade chloroquine resistance in western Indonesia, a long distance from the known hot spot on the Island of Papua.

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