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Afghanistan

Elimination of Plasmodium falciparum malaria in Tajikistan

June 6, 2017 - 15:30 -- Open Access
Author(s): 
Anatoly V. Kondrashin, Azizullo S. Sharipov, Evgeny N. Morozov, et al.
Reference: 
Malaria Journal 2017 16:226, 30 May 2017

Malaria was eliminated in Tajikistan by the beginning of the 1960s. However, sporadic introduced cases of malaria occurred subsequently probably as a result of transmission from infected mosquito Anopheles flying over river the Punj from the border areas of Afghanistan.

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Evidence of metabolic mechanisms playing a role in multiple insecticides resistance in Anopheles stephensi populations from Afghanistan

March 9, 2017 - 15:46 -- Open Access
Author(s): 
Noor Halim Zahid Safi, Abdul Ali Ahmadi, Sami Nahzat, Seyyed Payman Ziapour, Seyed Hassan Nikookar, Mahmoud Fazeli-Dinan, Ahmadali Enayati and Janet Hemingway
Reference: 
Malaria Journal 2017 16:100, 3 March 2017

Based on the results, the reported resistance to pyrethroid and organophosphate insecticides, and tolerance to bendiocarb in the Kunar and Nangarhar populations of An. stephensi from Afghanistan are likely to be caused by a range of metabolic mechanisms, including esterases, P450s and GSTs combined with target site insensitivity in AChE.

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Clinical trials of artesunate plus sulfadoxine-pyrimethamine for Plasmodium falciparum malaria in Afghanistan: maintained efficacy a decade after introduction

March 1, 2016 - 17:50 -- Open Access
Author(s): 
Ghulam Rahim Awab, Mallika Imwong, Charles J. Woodrow, et al.
Reference: 
Malaria Journal 2016 15:121, 25 February 2016

These data confirm maintained efficacy 10 years after introduction of artesunate plus SP as combination treatment of P. falciparum in Afghanistan.

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Towards a strategy for malaria in pregnancy in Afghanistan: analysis of clinical realities and women’s perceptions of malaria and anaemia

November 4, 2015 - 14:01 -- Open Access
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Author(s): 
Natasha Howard, Sayed Enayatullah, Nader Mohammad, Ismail Mayan, Zohra Shamszai, Mark Rowland, Toby Leslie
Reference: 
Malaria Journal 2015, 14:431 (4 November 2015)

Given the low malaria risk and reported avoidance of medication during pregnancy, intermittent preventive treatment is hard to justify or implement.

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Risk Assessment and Prevention of Malaria Among Italian Troops in Afghanistan, 2002 to 2011

January 7, 2014 - 09:12 -- Open Access
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Author(s): 
Mario S. Peragallo, Giuseppe Sarnicola, Daniela Boccolini, Roberto Romi and Giacomo Mammana
Reference: 
Journal of Travel Medicine, Volume 21, Issue 1, pages 24–32, January/February 2014

In spite of the decreasing compliance with chemoprophylaxis, suggesting a low perception of the risk of malaria, this study confirmed the good tolerability of mefloquine in the military.

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Prevalence and molecular basis of glucose-6-phosphate dehydrogenase deficiency in Afghan populations: implications for treatment policy in the region

July 9, 2013 - 12:08 -- Open Access
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Author(s): 
Leslie T, Moiz B, Mohammad N, Amanzai O, Rashid H, Jan S, Siddiqi AM, Nasir A, Beg MA, Vink M
Reference: 
Malaria Journal 2013, 12:230 (8 July 2013)
MalariaWorld

Prevalence of G6PD deficiency in Afghanistan varies considerably by ethnic group and is predominantly of the Mediterranean type.

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Prevalence of antifolate resistance mutations in Plasmodium falciparum isolates in Afghanistan

March 19, 2013 - 09:18 -- Open Access
Author(s): 
Awab GR, Pukrittayakamee S, Jamornthanyawat N, Yamin F, Dondorp AM, Day NP, White NJ, Woodrow CJ, Imwong M
Reference: 
Malaria Journal 2013, 12:96 (15 March 2013)
MalariaWorld

Background

Artesunate plus sulphadoxine-pyrimethamine (AS+SP) is now first-line treatment for Plasmodium falciparum infection in several south Asian countries, including Afghanistan. Molecular studies provide a sensitive means to investigate the current state of drug susceptibility to the SP component, and can also provide information on the likely efficacy of other potential forms of artemisinin-combination therapy.

Methods

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Overdiagnosis and mistreatment of malaria among febrile patients at primary healthcare level in Afghanistan: observational study

July 25, 2012 - 15:18 -- Patrick Sampao
Author(s): 
Toby Leslie, Amy Mikhail, Ismail Mayan, Mohammed Anwar, Sayed Bakhtash, Mohammed Nader, Clare Chandler, Christopher J M Whitty, Mark Rowland
Reference: 
BMJ 2012; 345

MalariaWorldTo assess the accuracy of malaria diagnosis and treatment at primary level clinics in Afghanistan

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Open Access | Field trial of three different Plasmodium vivax-detecting rapid diagnostic tests with and without evaporative cool box storage in Afghanistan

June 23, 2011 - 14:08 -- Kabogo Ndegwa
Author(s): 
Mikhail AF, Leslie TJ, Mayan MI, Zekria R, Mohammad N, Hasanzai MA, Safi N, Whitty CJ, Rowland M
Reference: 
Malaria Journal 2011, 10:169 (22 June 2011)

Of the three RDTs, the CSPfPan test was the most consistent and reliable, rendering it appropriate for this P. vivax predominant region.

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