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Pakistan

Prevalence of molecular markers of sulfadoxine–pyrimethamine and artemisinin resistance in Plasmodium falciparum from Pakistan

December 27, 2018 - 15:54 -- Open Access
Author(s): 
Adnan Yaqoob, Aamer Ali Khattak, Shannon Takala-Harrison, et al.
Reference: 
Malaria Journal 2018 17:471, 17 December 2018

The absence of the highly resistant PfDHFR/PfDHPS quintuple mutant parasites and the lack of PfK13 mutations associated with artemisinin resistance is consistent with AS + SP being effective in Pakistan.

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Population genetic structure of domain I of apical membrane antigen-1 in Plasmodium falciparum isolates from Hazara division of Pakistan

October 30, 2018 - 15:47 -- Open Access
Author(s): 
Sahib Gul Afridi, Muhammad Irfan, Habib Ahmad, Muneeba Aslam, Mehwish Nawaz, Muhammad Ilyas and Asifullah Khan
Reference: 
Malaria Journal 2018 17:389, 26 October 2018

The Pakistani P. falciparum isolates were found to maintain a distinct genetic pattern at HVR pfama1 with some extent of genetic relationship with geographically close Myanmar and Indian samples.

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NOT Open Access | Socioeconomic Condition and Prevalence of Malaria Fever in Pakistani Children: Findings from a Community Health Survey

June 15, 2018 - 16:23 -- NOT Open Access
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Author(s): 
Atta Muhammad Asif; Muhammad Ramzan Tahir ; Irshad Ahmad Arshad
Reference: 
Journal of Tropical Pediatrics, Volume 64, Issue 3, 1 June 2018, Pages 189–194

SEC has a significant impact on the prevalence of malaria fever in the context of different regions in Pakistan.

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Detection of asymptomatic carriers of malaria in Kohat district of Pakistan

January 23, 2018 - 16:05 -- Open Access
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Author(s): 
Muhammad Abdul Naeem, Suhaib Ahmed and Saleem Ahmed Khan
Reference: 
Malaria Journal 2018 17:44, 22 January 2018

 

The chances of detecting asymptomatic malaria carriers is significantly higher in the homestead of malaria patients than in the general population and for this purpose RT-PCR with EPF can be very useful in the diagnosis of malaria especially with low parasite density.

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Frequency of G6PD Mediterranean in individuals with and without malaria in Southern Pakistan

October 30, 2017 - 14:53 -- Open Access
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Author(s): 
Bushra Moiz, Haroon Muhammad Arshad, Ahmed Raheem, Hasan Hayat, Najia Karim Ghanchi and M. Asim Beg
Reference: 
Malaria Journal 2017 16:426, 24 October 2017

Cumulative allelic frequency for G6PD 563c.C>T was 0.0285 detected in 6 of 210 X-chromosomes in Southern Pakistan.

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Epidemiology and Clinical Burden of Malaria in the War-Torn Area, Orakzai Agency in Pakistan

February 8, 2016 - 19:47 -- Open Access
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Author(s): 
Asad Mustafa Karim, Irfan Hussain, Sumera Kausar Malik, Jung Hun Lee, Ill Hwan Cho, Young Bae Kim, Sang Hee Lee
Reference: 
PLoS Negl Trop Dis 10(1): e0004399

This overlooked distribution of P. vivax should be considered by malaria control strategy makers in the world and by the Government of Pakistan.

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Vivax malaria and chloroquine resistance: a neglected disease as an emerging threat

April 14, 2015 - 17:25 -- Open Access
Author(s): 
Waheed AA, Ghanchi NK, Rehman KA, Raza A, Mahmood SF, Beg MA
Reference: 
Malaria Journal 2015, 14 :146 (8 April 2015)

In Pakistan, Plasmodium vivax contributes to major malaria burden.

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PCR/RFLP-Based Analysis of Genetically Distinct Plasmodium vivax Population of Pvmsp-3alpha and Pvmsp-3beta genes in Pakistan

September 11, 2014 - 16:47 -- Open Access
Author(s): 
Khan S, Khan A, Khan S, Ayaz S, Attaullah S, Khan J, Khan M, Ali I, Shah A
Reference: 
Malaria Journal 2014, 13 :355 (9 September 2014)

The present study was aimed at observing the molecular epidemiology and genetic variation of Plasmodium vivax by analysing its merozoite surface protein-3α (msp-3α) and merozoite surface protein-3β (msp-3β) genes, by using suballele, species-specific, combined nested PCR/RFLP detection techniques.

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Tumour necrosis factor, interleukin-6 and interleukin-10 are possibly involved in Plasmodium vivax-associated thrombocytopaenia in southern Pakistani population

August 25, 2014 - 09:39 -- Open Access
Author(s): 
Raza A, Khan M, Ghanchi N, Raheem A, Beg MA
Reference: 
Malaria Journal 2014, 13 :323 (16 August 2014)

Cytokines may have a possible role in P. vivax-induced thrombocytopaenia in Pakistani population.

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Concurrent dengue and malaria infection in Lahore, Pakistan during the 2012 dengue outbreak

January 7, 2014 - 16:01 -- Open Access
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Author(s): 
Muhammad Zaman Khan Assir, Muhammad Adnan Masood, Hafiz Ijaz Ahmad
Reference: 
International Journal of Infectious Diseases, Volume 18, January 2014, Pages 41-46

The rate of isolated malaria and dengue–malaria co-infection was high in probable cases of dengue fever in our study. Except for jaundice, we could not find any significant between-group differences in the severity of the disease.

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