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Mozambique

Prevalence and clinical features of HIV and malaria co-infection in hospitalized adults in Beira, Mozambique

July 31, 2012 - 13:23 -- Kabogo Ndegwa
Author(s): 
Saracino A, Nacarapa EA, da Costa Massinga EA, Martinelli D, Scacchetti M, de Oliveira C, Antonich A, Galloni D, Ferro JJ, Macome CA
Reference: 
Malaria Journal 2012, 11:241 (26 July 2012)

MalariaWorldMalaria infection was rare in HIV-positive individuals treated with CTX for opportunistic infections, while no independent anti-malarial effect for NNRTIs was noted.

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Low antibodies against Plasmodium falciparum and imbalanced pro-inflammatory cytokines are associated with severe malaria in Mozambican children: a case-control study

May 31, 2012 - 06:52 -- Kabogo Ndegwa
Author(s): 
Rovira-Vallbona E, Moncunill G, Bassat Q, Aguilar R, Machevo S, Puyol L, Quintó L, Menéndez C, Chitnis CE, Alonso PL, Dobaño C, Mayor A
Reference: 
Malaria Journal 2012, 11:181 (30 May 2012)

MalariaWorldThe lower levels of antibodies found in children with SM compared to children with UM were not attributable to lower exposure to P. falciparum in the SM group. IgM against P. falciparum and specific IgG against a rosetting PfEMP1 domain may play a role in the control of SM, whereas an imbalanced pro-inflammatory cytokine response may exacerbate the severity of infection.

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NOT Open Access | Inadequate Efficacy of a New Formulation of Fosmidomycin-Clindamycin Combination in Mozambican Children Less than Three Years Old with Uncomplicated Plasmodium falciparum Malaria

May 15, 2012 - 14:14 -- Kabogo Ndegwa
Author(s): 
Miguel Lanaspa, Cinta Moraleda, Quique Bassat, et al.
Reference: 
Antimicrob. Agents Chemother. June 2012 vol. 56 no. 6 2923-2928

MalariaWorldThe combination of fosmidomycin and clindamycin (F/C) is effective in adults and older children for the treatment of malaria and could be an important alternative to existing artemisinin-based combinations (ACTs) if proven to work in younger children.

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Age-Dependent IgG Subclass Responses to Plasmodium falciparum EBA-175 Are Differentially Associated with Incidence of Malaria in Mozambican Children

February 1, 2012 - 07:51 -- Kabogo Ndegwa
Author(s): 
Carlota Dobaño, Diana Quelhas, Clara Menéndez, et al.
Reference: 
Clin Vaccine Immunol February 2012 vol. 19 no. 2 157-166

MalariaWorldPlasmodium falciparum blood-stage antigens such as merozoite surface protein 1 (MSP-1), apical membrane antigen 1 (AMA-1), and the 175-kDa erythrocyte binding antigen (EBA-175) are considered important targets of naturally acquired immunity to malaria.

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Prevalence of Malaria among Patients Attending Public Health Facilities in Maputo City, Mozambique.

December 8, 2011 - 15:35 -- Patrick Sampao
Author(s): 
Macedo de Oliveira A, Mutemba R, Morgan J, Streat E, Roberts J, Menon M, Mabunda S.
Reference: 
Am J Trop Med Hyg. 2011 Dec;85(6):1002-7.

MalariaWorldA malaria case was defined as a positive result for malaria by microscopy in a patient with fever or history of fever in the previous 24 hours.

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Open Access | What drives community adherence to indoor residual spraying (IRS) against malaria in Manhica district, rural Mozambique: a qualitative study

November 24, 2011 - 09:16 -- Kabogo Ndegwa
Author(s): 
Munguambe K, Pool R, Montgomery C, Bavo C, Nhacolo A, Fiosse L, Sacoor C, Nhalungo D, Mabunda S, Macete E, Alonso P
Reference: 
Malaria Journal 2011, 10:344 (23 November 2011)

MalariaWorldThe study suggests that the contribution of IRS to malaria and mosquito control is not entirely perceived by the beneficiaries, and that other as cost effective interventions such as insecticide-treated nets are favoured over IRS.

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Distinguishing Malaria from Severe Pneumonia among Hospitalized Children who Fulfilled Integrated Management of Childhood Illness Criteria for Both Diseases: A Hospital-Based Study in Mozambique

October 10, 2011 - 07:39 -- Patrick Sampao
Author(s): 
Quique Bassat, Sónia Machevo, Pedro L. Alonso, et al.
Reference: 
Am J Trop Med Hyg 2011 85:626-634

We investigated ways to increase diagnostic accuracy in patients hospitalized with clinical symptoms compatible with malaria and severe pneumonia, in an area with high a prevalence of infection with human immunodeficiency virus.

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Open Access | Investigating preferences for mosquito-control technologies in Mozambique with latent class analysis

July 26, 2011 - 06:40 -- Kabogo Ndegwa
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Author(s): 
Smith RA, Barclay VC, Findeis JL
Reference: 
Malaria Journal 2011, 10:200 (21 July 2011)

To become widely diffused, best practices suggest that end-users should be included in product development to ensure that preferred attributes or traits are considered.

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Open Access | Spatial and temporal patterns of malaria incidence in Mozambique

July 14, 2011 - 07:50 -- Kabogo Ndegwa
Author(s): 
Zacarias OP, Andersson M
Reference: 
Malaria Journal 2011, 10:189 (13 July 2011)

These results demonstrate the potential of climate predictors particularly, humidity and maximum temperature in explaining malaria incidence risk for the studied period in Maputo province.

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Open Access | The emergence of insecticide resistance in central Mozambique and potential threat on the successful indoor residual spraying malaria control programme

May 5, 2011 - 08:12 -- Kabogo Ndegwa
Author(s): 
Ana P Abilio, Immo Kleinschmidt, Michael Coleman, et al.
Reference: 
Malaria Journal 2011, 10:110 (2 May 2011)

Both An. gambiae s.s. and An. funestus were controlled effectively with the DDT-based IRS programme in Zambezia, reducing disease transmission and burden.

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