In children with malaria plasma VWF and propeptide levels are markedly elevated in both cerebral and mild paediatric malaria, with levels matching disease severity, and these normalize upon recovery.
It was found that most of the participants know about ACT and treatment guidelines for malaria.
We investigated PfCRT 76T mutation in severe and non-severe malaria in Southern Mali.
Studies conducted in The Gambia and Malawi suggest that blood group O confers a higher risk of active placental infection in primiparae, but a significantly lower risk in multiparae.
We examined the brains of 50 Malawian children who satisfied the clinical definition of cerebral malaria (CM) during life; 37 children had sequestration of infected red blood cells (iRBCs) and no other cause of death, and 13 had a nonmalarial cause of death with no cerebral sequestration.
Women with either acute, or acute and chronic placental malaria were less likely to have iron deficiency than women without placental malaria infection .
Children who suffer retinopathy-positive CM at preschool age are at greater risk of developmental delay, particularly with respect to language development.
The extent of similarity between P. falciparum and P. malariae population structure described by the high level of multiple infection, the lack of significant population differentiation or haplotype clustering and lack of linkage disequilibrium is surprising given the differences in the biological features of these species that suggest a reduced potential for out-crossing and transmission in P. malariae.
In addition to parasite resistance, inadequate levels of exposure to antimalarial drugs may contribute to treatment failure.
A mosquito survey was carried out on the island of Likoma in Lake Malawi with a view to collecting baseline data to determine the feasibility of implementing an integrated malaria vector control programme.