Clinical and basic research, which is mostly funded externally, in the fields of malaria in pregnancy, severe malaria and vector and/or agent dynamics dominated, while health policy and system research was least supported.
Malawi’s efforts to scale up ownership of long-lasting, insecticide-treated bed nets are effective in increasing reported use.
International WHO recommendations facilitated a smooth policy change driven by motivated local leadership with technical and financial support from development partners.
Travel was the main factor influencing the incidence of malaria illness among residents of urban Blantyre compared with peri-urban areas.
SP resistance selection pressures have been retained in the Malawian population, with known resistance dhfr mutations at fixation, complemented by a novel gch1 promoter duplication.
Pyrethroid resistance was detected in An. funestus and An. arabiensis populations across Malawi and has worsened over the last 5 years.
Antibodies to placental-binding infected erythrocytes may be associated with higher haemoglobin levels in pregnancy, whereas antibodies to other malaria antigens may instead be markers of malaria exposure.
School-age children frequently carry gametocytes in communities of southern Malawi and represent an under-recognized reservoir of infection
This study illustrates the complex interplay between geographic access and gender dynamics in shaping decisions on whether and when formal treatment is sought for febrile children in Chikwawa District.
Overall, the study identified facilitating factors to malaria research utilization for policy development in Malawi.