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Malawi

Patterns and determinants of malaria risk in urban and peri-urban areas of Blantyre, Malawi

December 14, 2016 - 17:25 -- Open Access
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Author(s): 
Don P. Mathanga, Atupele Kapito Tembo, Mark L. Wilson, et al.
Reference: 
Malaria Journal 2016 15:590, 8 December 2016

Travel was the main factor influencing the incidence of malaria illness among residents of urban Blantyre compared with peri-urban areas.

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Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi

November 30, 2016 - 17:32 -- Open Access
Author(s): 
Matt Ravenhall, Ernest Diez Benavente, Taane G. Clark, et al.
Reference: 
Malaria Journal 2016 15:575, 29 November 2016

SP resistance selection pressures have been retained in the Malawian population, with known resistance dhfr mutations at fixation, complemented by a novel gch1 promoter duplication.

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Increasing insecticide resistance in Anopheles funestus and Anopheles arabiensis in Malawi, 2011–2015

November 30, 2016 - 16:06 -- Open Access
Author(s): 
Themba Mzilahowa, Martin Chiumia, John E. Gimnig, et al.
Reference: 
Malaria Journal 2016 15:563, 22 November 2016

Pyrethroid resistance was detected in An. funestus and An. arabiensis populations across Malawi and has worsened over the last 5 years.

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Association between malaria immunity and pregnancy outcomes among Malawian pregnant women receiving nutrient supplementation

November 16, 2016 - 17:16 -- Open Access
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Author(s): 
Upeksha P. Chandrasiri, Freya J. I. Fowkes, James G. Beeson, Jack S. Richards, Steve Kamiza, Kenneth Maleta, Per Ashorn and Stephen J. Rogerson
Reference: 
Malaria Journal 2016 15:547, 9 November 2016

Antibodies to placental-binding infected erythrocytes may be associated with higher haemoglobin levels in pregnancy, whereas antibodies to other malaria antigens may instead be markers of malaria exposure.

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High prevalence of Plasmodium falciparum gametocyte infections in school-age children using molecular detection: patterns and predictors of risk from a cross-sectional study in southern Malawi

November 8, 2016 - 17:16 -- Open Access
Author(s): 
Jenna E. Coalson, Jenny A. Walldorf, Mark L. Wilson, et al.
Reference: 
Malaria Journal 2016 15:527, 4 November 2016

School-age children frequently carry gametocytes in communities of southern Malawi and represent an under-recognized reservoir of infection

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Increasing understanding of the relationship between geographic access and gendered decision-making power for treatment-seeking for febrile children in the Chikwawa district of Malawi

October 26, 2016 - 17:36 -- Open Access
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Author(s): 
Victoria L. Ewing, Rachel Tolhurst, Andrew Kapinda, Esther Richards, Dianne J. Terlouw and David G. Lalloo
Reference: 
Malaria Journal 2016 15:521, 24 October 2016

This study illustrates the complex interplay between geographic access and gender dynamics in shaping decisions on whether and when formal treatment is sought for febrile children in Chikwawa District.

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Facilitating factors and barriers to malaria research utilization for policy development in Malawi

October 26, 2016 - 17:24 -- Open Access
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Author(s): 
Chikondi A. Mwendera, Christiaan de Jager, Herbert Longwe, Kamija Phiri, Charles Hongoro and Clifford M. Mutero
Reference: 
Malaria Journal 2016 15:512, 19 October 2016

Overall, the study identified facilitating factors to malaria research utilization for policy development in Malawi.

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Integrated paediatric fever management and antibiotic over-treatment in Malawi health facilities: data mining a national facility census

August 8, 2016 - 10:43 -- Open Access
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Author(s): 
Emily White Johansson, Katarina Ekholm Selling, Humphreys Nsona, Bonnie Mappin, Peter W. Gething, Max Petzold, Stefan Swartling Peterson and Helena Hildenwall
Reference: 
Malaria Journal 2016 15:396, 4 August 2016

Integrated paediatric fever management was sub-optimal for completed assessments and antibiotic targeting despite common compliance to malaria treatment guidelines.

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Adherence to national guidelines for the diagnosis and management of severe malaria: a nationwide, cross-sectional survey in Malawi, 2012

July 23, 2016 - 17:06 -- Open Access
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Author(s): 
Monica P. Shah, Melissa Briggs-Hagen, Kim A. Lindblade, et al.
Reference: 
Malaria Journal 2016 15:369, 19 July 2016

A majority of patients diagnosed with severe malaria received the recommended IV therapy in accordance with national treatment guidelines.

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Delayed acquisition of Plasmodium falciparum antigen-specific CD4+ T cell responses in HIV-exposed uninfected Malawian children receiving daily cotrimoxazole prophylaxis

May 16, 2016 - 17:34 -- Open Access
Author(s): 
Herbert Longwe, Kamija S. Phiri, Nyanyiwe M. Mbeye, Thandile Gondwe, Wilson L. Mandala and Kondwani C. Jambo
Reference: 
Malaria Journal 2016 15:264

The results demonstrate that there is delayed acquisition of P. falciparum-specific IFN-γ-producing CD4+ T cells in HEU children on daily cotrimoxazole prophylaxis, which is evident at 6 and 12 months of age in comparison to HUU age-matched controls.

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