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Gambia

A long-term follow-up study on otoacoustic emissions testing in paediatric patients with severe malaria in Gabon

July 1, 2019 - 15:36 -- Open Access
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Author(s): 
Elisa Reiterer, Simon Reider, Joachim Schmutzhard, et al.
Reference: 
Malaria Journal 2019 18:212, 24 June 2019

In a previous study, severe and cerebral malaria have been connected with acute cochlear malfunction in children, demonstrated by a decrease of transitory evoked otoacoustic emissions (TEOAEs) reproducibility. This study aims to determine whether cochlear malfunction persists for 4 years after recovery from severe malaria in a subset of the previous study’s collective. Follow-up TEOAEs were performed on site (CERMEL, Hôpital Albert Schweitzer, Lambaréné, Gabon) or at the participants’ homes; 33 out of 90 participants included in the initial investigation by Schmutzhard et al. could be retrieved and were re-examined, 31/33 could be included. Of the 57 missing participants, 51 could not be contacted, 1 had moved away, 4 refused to cooperate, and 1 had died.

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Reduced mosquito survival in metal-roof houses may contribute to a decline in malaria transmission in sub-Saharan Africa

June 3, 2019 - 15:05 -- Open Access
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Author(s): 
Steve W. Lindsay, Musa Jawara, Umberto D’Alessandro, et al.
Reference: 
Scientific Reports 9, Article number: 7770

In The Gambia, metal-roof houses were hotter during the day than thatched-roof houses. After 24 h, the mortality of Anopheles gambiae, the principal African malaria vector, was 38% higher in metal-roof houses than thatched ones.

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Community perspectives on treating asymptomatic infections for malaria elimination in The Gambia

February 19, 2019 - 14:26 -- Open Access
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Author(s): 
Fatou Jaiteh, Yoriko Masunaga, Joseph Okebe, Umberto D’Alessandro, Julie Balen, John Bradley, Charlotte Gryseels, Joan Muela Ribera and Koen Peeters Grietens
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Malaria Journal 2019 18:39, 18 February 2019

Treating asymptomatic malaria with pharmaceuticals was considered acceptable.

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Emergence of knock-down resistance in the Anopheles gambiae complex in the Upper River Region, The Gambia, and its relationship with malaria infection in children

May 22, 2018 - 14:10 -- Open Access
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Author(s): 
Anne L. Wilson, Margaret Pinder, Steven W. Lindsay, et al.
Reference: 
Malaria Journal 2018 17:205, 18 May 2018

As a result of colinearity between homozygous Vgsc-1014F mutations and An. gambiae s.s., it was not possible to determine whether insecticide resistance or species composition increased the risk of childhood malaria infection.

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Sustained Ex Vivo Susceptibility of Plasmodium falciparum to Artemisinin Derivatives but Increasing Tolerance to Artemisinin Combination Therapy Partner Quinolines in The Gambia

November 25, 2017 - 14:55 -- Open Access
Author(s): 
Alfred Amambua-Ngwa, Joseph Okebe, Umberto D'Alessandro, et al.
Reference: 
Antimicrob. Agents Chemother. December 2017 vol. 61 no. 12 e00759-17

Antimalarial interventions have yielded a significant decline in malaria prevalence in The Gambia, where artemether-lumefantrine (AL) has been used as a first-line antimalarial for a decade.

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Monitoring malaria using health facility based surveys: challenges and limitations

April 26, 2016 - 16:17 -- Open Access
Author(s): 
Oduro A, Maya E, Akazili J, Baiden F, Koram K, Bojang K
Reference: 
BMC Public Health 2016, 16 :354 (21 April 2016)

The study design involved an age stratified cross sectional surveys that were conducted during the wet season in 2008 and in the 2009 during the dry season. Participants were patients attending clinics in six health centres and the representative populations from the catchment communities of the health centres.

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‘Some anti-malarials are too strong for your body, they will harm you.’ Socio-cultural factors influencing pregnant women’s adherence to anti-malarial treatment in rural Gambia

April 11, 2016 - 16:30 -- Open Access
Author(s): 
Fatou Jaiteh, Susan Dierickx, Charlotte Gryseels, Sarah O’Neill, Umberto D’Alessandro, Susana Scott, Julie Balen and Koen Peeters Grietens
Reference: 
Malaria Journal 2016 15:195, 11 April 2016

Improving women’s knowledge of malaria in pregnancy is not sufficient to assure adherence to anti-malarial treatment.

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Does insecticide resistance contribute to heterogeneities in malaria transmission in The Gambia?

March 16, 2016 - 17:43 -- Open Access
Author(s): 
Kevin Ochieng’ Opondo, David Weetman, Musa Jawara, Mathurin Diatta, Amfaal Fofana, Florence Crombe, Julia Mwesigwa, Umberto D’Alessandro and Martin James Donnelly
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Malaria Journal 2016 15:166, 15 March 2016

Whilst causality of relationships requires further investigation, variation in vector species and insecticide resistance in The Gambia is associated with malaria endemicity; with a notably higher prevalence of infection and insecticide resistance in the east of the country.

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Non-falciparum malaria infections in pregnant women in West Africa

February 2, 2016 - 19:06 -- Open Access
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Author(s): 
John Williams, Fanta Njie, Daniel Chandramohan, et al.
Reference: 
Malaria Journal 2016 15:53, 29 January 2016

Non-falciparum infections were infrequent in the populations studied, rarely detected when present as a mono-infection and unlikely to have had an important impact on the outcome of pregnancy in the communities  studied due to the small number of women infected with non-falciparum parasites.

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Serology describes a profile of declining malaria transmission in Farafenni, The Gambia

October 23, 2015 - 06:16 -- Open Access
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Author(s): 
Lotus van den Hoogen, Jamie Griffin, Chris Drakeley, et al.
Reference: 
Malaria Journal 2015, 14:416 (22 October 2015)

This analysis shows accurate reconstruction of historical malaria transmission patterns in the Farafenni area using anti-malarial antibody responses.

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