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Angola

Open Access | Plasmodium falciparum isolates from Angola show the StctVMNT haplotype in the pfcrt gene

June 22, 2010 - 10:23 -- Kabogo Ndegwa
Author(s): 
Gama BE, Pereira de Carvalho GA, Lutucuta Kosi FJ, Almeida de Oliveira NK, Fortes F, Rosenthal PJ, Daniel Ribeiro CT, Ferreira da Cruz M
Reference: 
Malaria Journal 2010, 9:174 (18 June 2010)

The high prevalence of the pfcrt SVMNT haplotype and the pfmdr1 86Y mutation confirm high-level chloroquine resistance and might suggest reduced efficacy of amodiaquine in Angola. Further studies must be encouraged to examine the in vitro sensitivity of pfcrt SVMNT parasites to artesunate and amodiaquine for better conclusive data.

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Open Access | Transforming Growth Factor Beta 2 and Heme Oxygenase 1 Genes Are Risk Factors for the Cerebral Malaria Syndrome in Angolan Children

June 18, 2010 - 11:23 -- Kabogo Ndegwa
Author(s): 
Maria Rosário Sambo, Maria Jesus Trovoada, Carla Benchimol, Vatúsia Quinhentos, Lígia Gonçalves, Rute Velosa, Maria Isabel Marques, Nuno Sepúlveda, Taane G. Clark, Stefan Mustafa, Oswald Wagner, António Coutinho, Carlos Penha-Gonçalves
Reference: 
PLoS ONE 5(6): e11141.

These results represent the first report on CM genetic risk factors in Angolan children and suggest the novel hypothesis that genetic variants of the TGFB2 and HMOX1 genes may contribute to confer a specific risk of developing the CM syndrome in patients with severe P. falciparum malaria.

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Open Access | Bayesian Geostatistical Modeling of Malaria Indicator Survey Data in Angola

March 25, 2010 - 15:33 -- Ingeborg van Schayk
Author(s): 
Laura Gosoniu, Andre Mia Veta, Penelope Vounatsou
Reference: 
PLoS ONE 5(3): e9322. doi:10.1371/journal.pone.0009322

The 2006–2007 Angola Malaria Indicator Survey (AMIS) is the first nationally representative household survey in the country assessing coverage of the key malaria control interventions and measuring malaria-related burden among children under 5 years of age.

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Open Access | Difficulties in organizing first indoor spray programme against malaria in Angola under the President's Malaria Initiative

January 10, 2010 - 15:18 -- Ingeborg van Schayk
Author(s): 
Martinho Somandjinga; Manuel Lluberas; William R Jobin
Reference: 
Bull World Health Organ vol.87 no.11 Genebra Nov. 2009

Unfortunately malaria transmission in Africa is often assessed using routine administrative reports from local health units, which are plagued by sporadic reporting failures. It is unfortunate that WHO is also trying to plan and evaluate its malaria control efforts based on these same kinds of inadequate administrative reports.

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Open Access | Quality of malaria case management at outpatient health facilities in Angola

December 8, 2009 - 12:30 -- Ingeborg van Schayk
Author(s): 
Alexander K Rowe, Gabriel F Ponce de Leon, Jules Mihigo, Ana Carolina FS Santelli, Nathan P Miller, Pedro Van-Dunem
Reference: 
Malaria Journal 2009, 8:275 (2 December 2009)

As problems identified in this survey are not unique to Angola, better strategies for improving Health Workers performance are urgently needed.

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Lessons learned: Difficulties in organizing first indoor spray programme against malaria in Angola under the President’s Malaria Initiative

December 2, 2009 - 09:39 -- Ingeborg van Schayk
Author(s): 
Martinho Somandjinga a, Manuel Lluberas b & William R Jobin c
Reference: 
Bulletin of the World Health Organization 2009;87:871-874. doi: 10.2471/BLT.08.052514

The first PMI programme to control malaria in Africa failed to have an impact in southern Angola because of hurried and inadequate preparation, based primarily on administrative reports of malaria prevalence.

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