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Ethiopia

Sero-identification of the aetiologies of human malaria exposure (Plasmodium spp.) in the Limu Kossa District of Jimma Zone, South western Ethiopia

September 2, 2019 - 15:27 -- Open Access
Author(s): 
Sindew Mekasha Feleke, Bokretsion Gidey Brhane, Hassen Mamo, Ashenafi Assefa, Adugna Woyessa, Guilherme Maerschner Ogawa and Vitaliano Cama
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Malaria Journal 2019 18:292, 27 August 2019

Malaria remains a very important public health problem in Ethiopia. Currently, only Plasmodium falciparum and Plasmodium vivax are considered in the malaria diagnostic and treatment policies. However, the existence and prevalence of Plasmodium ovale spp. and Plasmodium malariae in Ethiopia have not been extensively investigated. The objective of this study was to use a multiplex IgG antibody detection assay to evaluate evidence for exposure to any of these four human malaria parasites among asymptomatic individuals.

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Multiplex serology demonstrate cumulative prevalence and spatial distribution of malaria in Ethiopia

July 23, 2019 - 15:31 -- Open Access
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Author(s): 
Ashenafi Assefa, Ahmed Ali Ahmed, Jimee Hwang, et al.
Reference: 
Malaria Journal 2019 18:246, 22 July 2019

Measures of malaria burden using microscopy and rapid diagnostic tests (RDTs) in cross-sectional household surveys may incompletely describe the burden of malaria in low-transmission settings. This study describes the pattern of malaria transmission in Ethiopia using serological antibody estimates derived from a nationwide household survey completed in 2015.

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Quality of fixed dose artemether/lumefantrine products in Jimma Zone, Ethiopia

July 15, 2019 - 16:14 -- Open Access
Author(s): 
Sileshi Belew, Sultan Suleman, Bart De Spiegeleer, et al.
Reference: 
Malaria Journal 2019 18:236, 15 July 2019

Malaria caused by Plasmodium vivax and Plasmodium falciparum is among the major public health problems in most endemic areas of the world. Artemisinin-based combination therapy (ACT) has been recommended as a first-line treatment for uncomplicated Plasmodium falciparum malaria almost in all endemic regions. Since ineffectively regulated medicines in resource limited settings could favour infiltration of poor quality anti-malarial medicines into pharmaceutical supply chain and jeopardize a positive treatment outcome, regular monitoring of the quality of anti-malarial medicines is critical. Thus, the aim of this study was to assess the quality of fixed dose combination (FDC) artemether (ART)/lumefantrine (LUM) tablets available in Jimma zone, Ethiopia.

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Bio-efficacy and physical integrity of piperonylbutoxide coated combination net (PermaNet® 3.0) against pyrethroid resistant population of Anopheles gambiae s.l. and Culex quinquefasciatus mosquitoes in Ethiopia

July 8, 2019 - 17:01 -- Open Access
Author(s): 
Abaynesh Birhanu, Abebe Asale and Delenasaw Yewhalaw
Reference: 
Malaria Journal 2019 18:224, 4 July 2019

PermaNet® 3.0 is a deltamethrin-treated combination long-lasting insecticidal net with the addition of synergist piperonylbutoxide (PBO) on its roof section. It is designed to overcome the challenge posed by pyrethroid resistant vector populations against mainstream long-lasting insecticidal nets impregnated with pyrethroids only. The objective of this study was to determine insecticide resistance status of Anopheline and Culicine mosquitoes, to evaluate the bio-efficacy of PermaNet® 3.0 nets and to assess household factors affecting the physical integrity of PermaNet® 3.0 after 3 years of use.

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Ten years malaria trend at Arjo-Didessa sugar development site and its vicinity, Southwest Ethiopia: a retrospective study

April 29, 2019 - 13:11 -- Open Access
Author(s): 
Dawit Hawaria, Hallelujah Getachew, Guofa Zhong, Assalif Demissew, Kasahun Habitamu, Beka Raya, Ming-Chieh Lee, Delenasaw Yewhalaw and Guiyun Yan
Reference: 
Malaria Journal 2019 18:145, 24 April 2019

The trend analysis of malaria data from health facilities is useful for understanding dynamics of malaria epidemiology and inform for future malaria control planning. Changes in clinical malaria characteristics, like gender and age distribution are good indicators of declining malaria transmission. This study was conducted to determine the malaria trend at Arjo-Didessa sugar development site and its vicinity, southwest Ethiopia, from 2008 to 2017.

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Long-lasting insecticidal nets and indoor residual spraying may not be sufficient to eliminate malaria in a low malaria incidence area: results from a cluster randomized controlled trial in Ethiopia

April 22, 2019 - 12:33 -- Open Access
Author(s): 
Eskindir Loha, Wakgari Deressa, Bernt Lindtjørn, et al.
Reference: 
Malaria Journal 2019 18:141, 18 April 2019

The clinical malaria incidence and anaemia prevalence were similar in the four study groups.

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Sequence-based identification of Anopheles species in eastern Ethiopia

April 22, 2019 - 12:21 -- Open Access
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Author(s): 
Tamar E. Carter, Solomon Yared, Shantoy Hansel, Karen Lopez and Daniel Janies
Reference: 
Malaria Journal 2019 18:135, 16 April 2019

The lack of clarity from COI sequence analysis highlights potential challenges of species identification within species complexes.

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Environmental and meteorological factors linked to malaria transmission around large dams at three ecological settings in Ethiopia

February 28, 2019 - 15:42 -- Open Access
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Author(s): 
Solomon Kibret, G. Glenn Wilson, Darren Ryder, Habte Tekie and Beyene Petros
Reference: 
Malaria Journal 2019 18:54, 26 February 2019

This study confirmed that reservoir-associated factors (distance from reservoir shoreline, monthly average reservoir water level, monthly water level change) were important predictors of increased malaria incidence in villages around Ethiopian dams in all elevation settings.

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Evaluation of toxicity of clothianidin (neonicotinoid) and chlorfenapyr (pyrrole) insecticides and cross-resistance to other public health insecticides in Anopheles arabiensis from Ethiopia

February 26, 2019 - 15:22 -- Open Access
Author(s): 
Kendra Dagg, Seth Irish, Ryan E. Wiegand, Josephat Shililu, Delenasaw Yewhalaw and Louisa A. Messenger
Reference: 
Malaria Journal 2019 18:49, 22 February 2019

The putative diagnostic doses of clothianidin and chlorfenapyr are appropriate for monitoring resistance in An. arabiensis from Ethiopia.

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Treatments used for malaria in young Ethiopian children: a retrospective study

December 6, 2018 - 16:43 -- Open Access
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Author(s): 
Abyot Endale Gurmu, Teresa Kisi, Habteweld Shibru, Bertrand Graz and Merlin Willcox
Reference: 
Malaria Journal 2018 17:451, 5 December 2018

In this study, only 30% of children took the recommended first-line treatment.

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