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Sudan

Genetic polymorphism of the N-terminal region in circumsporozoite surface protein of Plasmodium falciparum field isolates from Sudan

October 7, 2019 - 15:17 -- Open Access
Author(s): 
Nouh S. Mohamed, Musab M. Ali Albsheer, Mohamed M. Elbasheir, et al.
Reference: 
Malaria Journal 2019 18:333, 1 October 2019

Malaria caused by Plasmodium falciparum parasite is still known to be one of the most significant public health problems in sub-Saharan Africa. Genetic diversity of the Sudanese P. falciparum based on the diversity in the circumsporozoite surface protein (PfCSP) has not been previously studied. Therefore, this study aimed to investigate the genetic diversity of the N-terminal region of the pfcsp gene.

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Plasmodium vivax cerebral malaria in an adult patient in Sudan

September 23, 2019 - 14:18 -- Open Access
Author(s): 
Maowia M. Mukhtar, Omer A. Eisawi, Seth A. Amanfo, Elwaleed M. Elamin, Zeinab S. Imam, Faiza M. Osman and Manasik E. Hamed
Reference: 
Malaria Journal 2019 18:316, 18 September 2019

Plasmodium vivax infection is rising in sub-Saharan Africa, where Plasmodium falciparum is responsible for more than 90% of malaria cases. While P. vivax is identified as a major cause of severe and cerebral malaria in South east Asia, the Pacific and South America, most of the severe and cerebral cases in Africa were attributed to P. falciparum. Cases of severe malaria due to P. vivax are emerging in Africa. A few severe P. vivax cases were reported in Eastern Sudan and they were underestimated due to the lack of accurate diagnosis, low parasitaemia and seldom use of rapid diagnostic tests (RDTs).

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Severe malaria management: current situation, challenges and lessons learned from Gezira State, Sudan

May 14, 2019 - 15:52 -- Open Access
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Author(s): 
Fahad A. Elnour, Mohammed E. A. Alagib, Devendra Bansal, Elmoubasher Abu Baker Abd Farag and Elfatih M. Malik
Reference: 
Malaria Journal 2019 18:170, 14 May 2019

The present study aimed to evaluate the management of severe malaria at Gezira State hospitals in Sudan by assessing hospital readiness, health care provider knowledge and the care received by severe malaria patients.

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Diversity pattern of Duffy binding protein sequence among Duffy-negatives and Duffy-positives in Sudan

August 21, 2018 - 14:34 -- Open Access
Author(s): 
Mohammad Rafiul Hoque, Mohammed Mohieldien Abbas Elfaki, Md Atique Ahmed, Seong-Kyun Lee, Fauzi Muh, Musab M. Ali Albsheer, Muzamil Mahdi Abdel Hamid and Eun-Taek Han
Reference: 
Malaria Journal 2018 17:297, 17 August 2018

This is the first pvdbp genetic diversity study from an African country. Sudanese isolates display high haplotype diversity and the gene is under selective pressure.

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Anopheles arabiensis in Sudan: a noticeable tolerance to urban polluted larval habitats associated with resistance to Temephos

May 22, 2018 - 14:09 -- Open Access
Author(s): 
Rasha S. Azrag and Babiker H. Mohammed
Reference: 
Malaria Journal 2018 17:204, 18 May 2018

The present study reveals that minor populations of An. arabiensis larval forms are adapted to breed in polluted urban habitats, which further influenced susceptibility to Temephos, especially for the melanic larval forms.

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Placental malaria and its effect on pregnancy outcomes in Sudanese women from Blue Nile State

September 19, 2017 - 15:14 -- Open Access
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Author(s): 
Samia A. Omer, Hagir E. Idress, Suad M. Sulaiman, et al.
Reference: 
Malaria Journal 2017 16:374, 16 September 2017

During the study, there was a high prevalence of placental malaria in Blue Nile State-Sudan, as the enhanced control activities were not practiced, leading to adverse pregnancy outcomes, such as maternal anaemia and LBW.

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Efficacies of DHA–PPQ and AS/SP in patients with uncomplicated Plasmodium falciparum malaria in an area of an unstable seasonal transmission in Sudan

April 26, 2017 - 15:35 -- Open Access
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Author(s): 
Abdelrahim O. Mohamed, Muzamil M. Abdel Hamid, Omer S. Mohamed, Nuha S. Elkando, Abdelmaroof Suliman, Mariam A. Adam, Fahad Awad Ali Elnour and Elfatih M. Malik
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Malaria Journal 2017 16:163, 20 April 2017

DHA–PPQ is an efficacious ACT and candidate for replacement of first-line treatment in Sudan while AS/SP showed high treatment failure rate and must be replaced.

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High efficacy of artemether-lumefantrine and declining efficacy of artesunate + sulfadoxine-pyrimethamine against Plasmodium falciparum in Sudan (2010–2015): evidence from in vivo and molecular marker studies

May 24, 2016 - 16:28 -- Open Access
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Author(s): 
Ahmed A. Adeel, Fahad Awad Ali Elnour, Rania A. Nada, et al.
Reference: 
Malaria Journal 2016 15:285, 21 May 2016

The findings of this study call for a need to review the Sudan malaria treatment policy.

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Not Open Access | Malaria Parasite Density Estimation using Actual and Assumed White Blood Cells Count in Children in Eastern Sudan

March 31, 2016 - 15:25 -- NOT Open Access
Author(s): 
Jalal A. Bilal, Gasim I. Gasim, Amani H. Karsani, Leana M. Elbashir and Ishag Adam
Reference: 
J Trop Pediatr (2016) 62 (2): 171-175.

 This study was conducted to determine the malaria parasite density among children using actual white blood cell (WBC) and the assumed WBC counts (8.0 × 109/l).

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Do frontline health care providers know enough about artemisinin–based combination therapy to rationally treat malaria? A cross-sectional survey in Gezira State, Sudan

March 31, 2015 - 17:36 -- Open Access
Author(s): 
Abeer A Mannan, Khalid A Elmardi, Yassir A Idris, Jonathan M Spector, Nahid A Ali, Elfatih M Malik
Reference: 
Malaria Journal 2015, 14:131 (26 March 2015)

Overall, ACT knowledge among frontline health care providers is very poor.

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