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Ghana

Diversity and immune responses against Plasmodium falciparum gametocytes in non-febrile school children living in Southern Ghana

August 6, 2019 - 16:12 -- Open Access
Author(s): 
Linda E. Amoah, Hamza B. Abagna, Ruth Ayanful-Torgby, Samuel O. Blankson and Nii A. Aryee
Reference: 
Malaria Journal 2019 18:265, 1 August 2019

Natural exposure to gametocytes can result in the development of immunity against the gametocyte by the host as well as genetic diversity in the gametocyte. This study evaluated the quantity and quality of natural immune responses against a gametocyte antigen, Pfs230 as well as the prevalence and diversity of gametocytes circulating in children living in two communities in southern Ghana.

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Dispensing practices for anti-malarials in the La Nkwantanang-Madina municipality, Greater Accra, Ghana: a cross-sectional study

August 5, 2019 - 16:23 -- Open Access
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Author(s): 
Charles Enyaah Amankwa, Harriet Affran Bonful, Kofi Agyabeng and Priscillia A. Nortey
Reference: 
Malaria Journal 2019 18:260, 30 July 2019

Despite recent strides made towards reducing the emergence of artemisinin resistance, inappropriate dispensing practices for anti-malarials in both private and public sectors affect treatment outcomes negatively. In Ghana, private retail pharmacies are the most accessible health facilities for managing diseases of common occurrence. However, there is growing concern about the number of patients harmed by dispensing errors in the management of malaria in retail pharmacies. Although considerable work has been done in this area, several questions regarding dispensing practices remain unanswered. This study, therefore, sought to investigate the predictors of appropriate dispensing practices for anti-malarials in community pharmacies in the La Nkwantanang-Madina municipality of Greater Accra, Ghana.

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Characterizing local-scale heterogeneity of malaria risk: a case study in Bunkpurugu-Yunyoo district in northern Ghana

March 20, 2019 - 15:42 -- Open Access
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Author(s): 
Punam Amratia, Paul Psychas, Benjamin Abuaku, Collins Ahorlu, Justin Millar, Samuel Oppong, Kwadwo Koram and Denis Valle
Reference: 
Malaria Journal 2019 18:81, 15 March 2019

This high variability in malaria prevalence is striking, given that this small area (approximately 30 km × 40 km) was purportedly homogeneous based on country-level spatial analysis, suggesting that fine-scale parasitaemia data might be critical to guide district-level programmatic efforts to prevent and control malaria.

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Prescribing patterns and compliance with World Health Organization recommendations for the management of severe malaria: a modified cohort event monitoring study in public health facilities in Ghana and Uganda

February 13, 2019 - 16:13 -- Open Access
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Author(s): 
H. Hilda Ampadu, Kwaku Poku Asante, Samuel Bosomprah, Samantha Akakpo, Pierre Hugo, Helga Gardarsdottir, Hubert G. M. Leufkens, Dan Kajungu and Alexander N. O. Dodoo
Reference: 
Malaria Journal 2019 18:36, 8 February 2019

Injectable AS is the most commonly prescribed medicine in the management of severe malaria in Ghana and Uganda.

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Diagnostic capacity, and predictive values of rapid diagnostic tests for accurate diagnosis of Plasmodium falciparum in febrile children in Asante-Akim, Ghana

December 27, 2018 - 15:30 -- Open Access
Author(s): 
Isabella A. Quakyi, George O. Adjei, Andrew A. Adjei, et al.
Reference: 
Malaria Journal 2018 17:468, 14 December 2018

The HRP2/pLDH RDTs showed comparable diagnostic accuracy in children presenting with an acute febrile illness to health facilities in a hard-to-reach rural area in Ghana.

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Prevalence of Plasmodium parasitaemia in blood donors and a survey of the knowledge, attitude and practices of transfusion malaria among health workers in a hospital in Kumasi, Ghana

November 21, 2018 - 15:22 -- Open Access
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Author(s): 
Kwame Agyemang Adusei, Alex Owusu-Ofori
Reference: 
PLoS ONE 13(11): e0206303

Malaria is one of the transfusion transmissible infections in malaria endemic countries such as Ghana.

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Detecting local risk factors for residual malaria in northern Ghana using Bayesian model averaging

October 2, 2018 - 15:33 -- Open Access
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Author(s): 
Justin Millar, Paul Psychas, Benjamin Abuaku, Collins Ahorlu, Punam Amratia, Kwadwo Koram, Samuel Oppong and Denis Valle
Reference: 
Malaria Journal 2018 17:343, 29 September 2018

This modelling framework offers an alternative approach to disease risk factor analysis that generates interpretable models, can reveal complex, nonlinear relationships, incorporates uncertainty in model selection, and produces accurate predictions.

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The prevalence of submicroscopic Plasmodium falciparum gametocyte carriage and multiplicity of infection in children, pregnant women and adults in a low malaria transmission area in Southern Ghana

September 18, 2018 - 16:15 -- Open Access
Author(s): 
Helena Lamptey, Michael Fokuo Ofori, Isabella A. Quakyi, et al.
Reference: 
Malaria Journal 2018 17:331, 17 September 2018

These findings suggest that children and pregnant women are particularly important as P. falciparum submicroscopic gametocyte reservoirs and represent important focus groups for control interventions.

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Sense of community and willingness to support malaria intervention programme in urban poor Accra, Ghana

August 13, 2018 - 16:24 -- Open Access
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Author(s): 
D. Yaw Atiglo, Reuben Tete Larbi, Mawuli Komla Kushitor, Adriana A. E. Biney, Paapa Yaw Asante, Naa Dodua Dodoo and F. Nii-Amoo Dodoo
Reference: 
Malaria Journal 2018 17:289, 10 August 2018

Different dimensions of sense of community are associated with community members’ willingness to provide labour, time or both to support the malaria eradication programme.

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Effectiveness of pregnant women’s active participation in their antenatal care for the control of malaria and anaemia in pregnancy in Ghana: a cluster randomized controlled trial

June 26, 2018 - 16:06 -- Open Access
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Author(s): 
Gifty Dufie Ampofo, Harry Tagbor and Imelda Bates
Reference: 
Malaria Journal 2018 17:238, 19 June 2018

Although its potential was evident, this study found no significant beneficial effect of women participating in their malaria and haemoglobin tests on pregnancy outcomes.

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