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Tanzania

Prescriber and patient-oriented behavioural interventions to improve use of malaria rapid diagnostic tests in Tanzania: facility-based cluster randomised trial

May 20, 2015 - 15:27 -- Open Access
Author(s): 
Bonnie Cundill, Hilda Mbakilwa, Hugh Reyburn, et al.
Reference: 
BMC Medicine 2015, 13:118

The primary outcome was the proportion of patients with a non-severe, non-malarial illness incorrectly prescribed a (recommended) antimalarial. Secondary outcomes investigated RDT uptake, adherence to results, and antibiotic prescribing.

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Not Open Access | α-Thalassaemia trait is associated with Antibody prevalence against Malaria Antigens AMA-1 and MSP-1

April 11, 2015 - 11:25 -- NOT Open Access
Author(s): 
Modibo Daou, Elimsaada Kituma, Reginald Kavishe, Jaffu Chilongola, Frank Mosha, André van der Ven, Bourema Kouriba, Teun Bousema, Robert Sauerwein and Ogobaro Doumbo
Reference: 
J Trop Pediatr (2015) 61 (2): 139-142.

A longitudinal study was conducted in a low endemic area in northern Tanzania to examine the influence of the α-thalassaemia trait on malaria incidence and antibody responses to malaria apical membrane antigen-1 (AMA-1) and merozoite surface protein1-19 (MSP-119).

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NOT Open Access | Bacteremia and Malaria in Tanzanian Children Hospitalized for Acute Febrile Illness

April 2, 2015 - 07:43 -- NOT Open Access
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Author(s): 
Ingrid S. Lundgren, Sonya L. Heltshe, Arnold L. Smith, Jerome Chibwana, Michal W. Fried, and Patrick E. Duffy
Reference: 
J Trop Pediatr (2015) 61 (2): 81-85.

We recorded the reason for presentation to a rural hospital in an area endemic for malaria in 909 children between January 2006 and March 2009.

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Monitoring of efficacy and safety of artemisinin-based anti-malarials for treatment of uncomplicated malaria: a review of evidence of implementation of anti-malarial therapeutic efficacy trials in Tanzania

March 31, 2015 - 17:42 -- Open Access
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Author(s): 
Alex Shayo, Joram Buza, Deus S Ishengoma
Reference: 
Malaria Journal 2015, 14:135 (29 March 2015)

ACT is efficacious and safe for treatment of uncomplicated malaria in Tanzania.

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Prevalence of Plasmodium falciparum anti-malarial resistance-associated polymorphisms in pfcrt, pfmdr1 and pfnhe1 in Muheza, Tanzania, prior to introduction of artemisinin combination therapy

March 31, 2015 - 17:31 -- Open Access
Author(s): 
Nahla B Gadalla, Gloria Tavera, Jianbing Mu, Edward R Kabyemela, Michael Fried, Patrick E Duffy, Juliana M Sá, Thomas E Wellems
Reference: 
Malaria Journal 2015, 14:129 (25 March 2015)

The pfcrt-CVIET chloroquine resistance haplotype dominated in the collection of P. falciparum samples from Muheza.

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NOT Open Access | Social determinants of malaria and health care seeking patterns among rice farming and pastoral communities in Kilosa District in central Tanzania

March 19, 2015 - 11:22 -- NOT Open Access
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Author(s): 
Elizabeth H. Shayo, Susan F. Rumisha, Malongo R.S. Mlozi, Veneranda M. Bwana, Benjamin K. Mayala, Robert C. Malima, Tabitha Mlacha, Leonard E.G. Mboera
Reference: 
Acta Tropica Volume 144, April 2015, Pages 41–49

This study was carried out to understand the role social determinants and health seeking behavior among rice farming and pastoral communities in Kilosa District in central Tanzania.

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Sibling species of the Anopheles funestus group, and their infection with malaria and lymphatic filarial parasites, in archived and newly collected specimens from northeastern Tanzania

March 10, 2015 - 13:10 -- Open Access
Author(s): 
Yahya A Derua, Michael Alifrangis, Stephen M Magesa, William N Kisinza, Paul E Simonsen
Reference: 
Malaria Journal 2015, 14:104 (6 March 2015)

The study indicated that the composition of the An. funestus group had remained rather stable during the study period, with An. funestus s.s. being the most predominant.

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In vivo antiplasmodial and toxicological effect of Maytenus senegalensis traditionally used in the treatment of malaria in Tanzania

March 9, 2015 - 14:54 -- Open Access
Author(s): 
Hamisi M Malebo, Victor Wiketye, Andrew Y Kitua, et al.
Reference: 
Malaria Journal 2015, 14:79 (14 February 2015)

In Tanzania and elsewhere, medicinal plants, including Maytenus senegalensis, are still widely used in the treatment of malaria and other ailments. The aim of the present study was to investigate the in vivo antiplasmodial and toxic effects in mice.

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Quality assurance of malaria rapid diagnostic tests used for routine patient care in rural Tanzania: microscopy versus real-time polymerase chain reaction

March 2, 2015 - 18:37 -- Open Access
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Author(s): 
Irene M Masanja, Meredith L McMorrow, Mussa B Maganga, Debora Sumari, Venkatachalam Udhayakumar, Peter D McElroy, S Kachur, Naomi W Lucchi
Reference: 
Malaria Journal 2015, 14:85 (19 February 2015)

Overall there was limited agreement among the three diagnostic approaches and neither microscopy nor qPCR appear to be good QA options for RDTs under field conditions.

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The use of mediation analysis to assess the effects of a behaviour change communication strategy on bed net ideation and household universal coverage in Tanzania

February 3, 2015 - 15:51 -- Open Access
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Author(s): 
Emily E Ricotta, Marc Boulay, Robert Ainslie, Stella Babalola, Megan Fotheringham, Hannah Koenker, Matthew Lynch
Reference: 
Malaria Journal 2015, 14:15 (21 January 2015)

The results of this study indicate that mediation analysis is an applicable new tool to assess SBCC campaigns.

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