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Tanzania

Diagnostic performance of CareStart™ malaria HRP2/pLDH test in comparison with standard microscopy for detection of uncomplicated malaria infection among symptomatic patients, Eastern Coast of Tanzania

November 11, 2019 - 16:02 -- Open Access
Author(s): 
George M. Bwire, Billy Ngasala, Manase Kilonzi, Wigilya P. Mikomangwa, Fatuma F. Felician and Appolinary A. R. Kamuhabwa
Reference: 
Malaria Journal 2019 18:354, 5 November 2019

CareStart™ malaria HRP2/pLDH (Pf/pan) combo test is one of the several rapid diagnostic tests (RDT) approved for diagnosis of malaria at the point of care in Tanzania. However, there are limited studies on the diagnostic performance of RDT after wide scale use in primary health care facilities in Tanzania. 

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Farmers’ pesticide usage practices in the malaria endemic region of North-Western Tanzania: implications to the control of malaria vectors

November 8, 2019 - 16:53 -- Open Access
Author(s): 
Anitha Philbert, Sylvester Leonard Lyantagaye & Gamba Nkwengulila
Reference: 
BMC Public Health volume 19, Article number: 1456 (2019)

Pesticides remain the mainstay for the control of agricultural pests and disease vectors. However, their indiscriminate use in agriculture has led to development of resistance to both crop pests and disease vectors. 

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Detection of malaria parasites in dried human blood spots using mid-infrared spectroscopy and logistic regression analysis

October 8, 2019 - 15:00 -- Open Access
Author(s): 
Emmanuel P. Mwanga, Elihaika G. Minja, Fredros O. Okumu, et al.
Reference: 
Malaria Journal 2019 18:341, 7 October 2019

Epidemiological surveys of malaria currently rely on microscopy, polymerase chain reaction assays (PCR) or rapid diagnostic test kits for Plasmodium infections (RDTs). This study investigated whether mid-infrared (MIR) spectroscopy coupled with supervised machine learning could constitute an alternative method for rapid malaria screening, directly from dried human blood spots.

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Bio-efficacy and wash resistance of MAGNet long-lasting insecticidal net against wild populations of Anopheles funestus in experimental huts in Muheza, Tanzania

October 7, 2019 - 15:24 -- Open Access
Author(s): 
Eliningaya J. Kweka, Patrick K. Tungu, Aneth M. Mahande, Humphrey D. Mazigo, Subira Sayumwe, Shandala Msangi, Lucile Lyaruu, John Waweru, William Kisinza and James Wangai
Reference: 
Malaria Journal 2019 18:335, 1 October 2019

The decline in malaria cases and vectors is major milestone in fighting against malaria. The efficacy of MAGNet long-lasting insecticidal nets (MAGNet LLIN), an alpha-cypermethrin incorporated long-lasting net, with the target dose ± 25% of 5.8 g active ingredient (AI)/kg (4.35–7.25 g AI/kg) was evaluated in six veranda-trap experimental huts in Muheza, Tanzania against freely flying wild population of Anopheles funestus.

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The impact on malaria of biannual treatment with azithromycin in children age less than 5 years: a prospective study

August 27, 2019 - 22:00 -- Open Access
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Author(s): 
Evan M. Bloch, Beatriz Munoz, Zakayo Mrango, Jerusha Weaver, Leonard E. G. Mboera, Tom M. Lietman, David J. Sullivan Jr. and Sheila K. West
Reference: 
Malaria Journal 2019 18:284, 23 August 2019

The MORDOR study, a cluster randomized clinical trial, showed that single-dose azithromycin (20 mg/kg) administered biannually for 2 years to preschool children reduced mortality; a study was conducted to determine its effect on clinical symptomatic episodes of malaria as a potential mechanism for mortality benefit.

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Assessment of the impact of availability and readiness of malaria services on uptake of intermittent preventive treatment in pregnancy (IPTp) provided during ANC visits in Tanzania

July 12, 2019 - 16:27 -- Open Access
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Author(s): 
Shraddha Bajaria, Charles Festo, Sigilbert Mrema, Josephine Shabani, Ellen Hertzmark and Ramadhani Abdul
Reference: 
Malaria Journal 2019 18:229, 9 July 2019

Intermittent preventive treatment during pregnancy (IPTp) is a highly-recommended intervention to prevent maternal and neonatal complications associated with malaria infection. Despite fairly high antenatal care (ANC) coverage in Tanzania, low IPTp uptake rates represent a gap in efforts to decrease complications attributed to malaria in pregnancy. The objective of this study was to examine if availability, readiness and managing authority are associated with uptake of IPTp during ANC.

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Spatio-temporal prevalence of malaria and anaemia in relation to agro-ecosystems in Mvomero district, Tanzania

July 12, 2019 - 16:25 -- Open Access
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Author(s): 
Susan F. Rumisha, Elizabeth H. Shayo and Leonard E. G. Mboera
Reference: 
Malaria Journal 2019 18:228, 9 July 2019

Agro-ecological systems have been associated with increased malaria intensity. This study determined association between different agro-ecological systems, prevalence of malaria parasitaemia and anaemia in Mvomero district, Tanzania.

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Malaria mosquito control in rice paddy farms using biolarvicide mixed with fertilizer in Tanzania: semi-field experiments

July 8, 2019 - 17:07 -- Open Access
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Author(s): 
Humphrey D. Mazigo, Leonard E. G. Mboera, Susan F. Rumisha and Eliningaya J. Kweka
Reference: 
Malaria Journal 2019 18:226, 8 July 2019

The wide distribution of malaria mosquito breeding sites within tropical environments limits the mosquito larval source management efforts to control malaria. Rice farming contributes substantially in supporting malaria mosquito productivity in tropical countries. To overcome this challenge, this study was carried out to determine the effect of applying a mixture of biolarvicide and fertilizer on mosquito larvae density in rice farms under semi-field conditions in Tanzania.

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Linking human behaviours and malaria vector biting risk in south-eastern Tanzania

June 11, 2019 - 15:07 -- Open Access
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Author(s): 
Marceline F. Finda, Irene R. Moshi, Fredros O. Okumu, et al.
Reference: 
PLoS ONE 14(6): e0217414

To accelerate malaria elimination in areas where core interventions such as insecticide-treated nets (ITNs) are already widely used, it is crucial to consider additional factors associated with persistent transmission.

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Autodissemination of pyriproxyfen suppresses stable populations of Anopheles arabiensis under semi-controlled settings

May 13, 2019 - 14:37 -- Open Access
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Author(s): 
Dickson Lwetoijera, Samson Kiware, Fredros Okumu, Gregor J. Devine and Silas Majambere
Reference: 
Malaria Journal 2019 18:166, 9 May 2019

Autodissemination of pyriproxyfen (PPF), i.e. co-opting adult female mosquitoes to transfer the insect growth regulator, pyriproxyfen (PPF) to their aquatic habitats has been demonstrated for Aedes and Anopheles mosquitoes. This approach, could potentially enable high coverage of aquatic mosquito habitats, including those hard to locate or reach via conventional larviciding. This study demonstrated impacts of autodissemination in crashing a stable and self-sustaining population of the malaria vector, Anopheles arabiensis under semi-field conditions in Tanzania.

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