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Kenya

Frequency and correlates of malaria over-treatment in areas of differing malaria transmission: a cross-sectional study in rural Western Kenya

March 5, 2015 - 17:44 -- Open Access
Author(s): 
Frankline M Onchiri, Patricia B Pavlinac, Benson O Singa, Jacqueline M Naulikha, Elizabeth A Odundo, Carey Farquhar, Barbra A Richardson, Grace John-Stewart, Judd L Walson
Reference: 
Malaria Journal 2015, 14:97 (1 March 2015)

Malaria over-treatment was common, particularly in Homa Bay, where the prevalence of malaria was extremely high.

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Active case surveillance, passive case surveillance and asymptomatic malaria parasite screening illustrate different age distribution, spatial clustering and seasonality in western Kenya

February 25, 2015 - 15:37 -- Open Access
Author(s): 
Guofa Zhou, Yaw A Afrane, Sameer Malla, Andrew K Githeko, Guiyun Yan
Reference: 
Malaria Journal 2015, 14:41 (28 January 2015)

The results revealed a significant difference in the age distribution of clinical cases between passive and active case surveillance, and between clinical case rate and asymptomatic parasite rate.

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The MSPDBL2 Codon 591 Polymorphism Is Associated with Lumefantrine In Vitro Drug Responses in Plasmodium falciparum Isolates from Kilifi, Kenya

February 18, 2015 - 12:57 -- Open Access
Author(s): 
Lynette Isabella Ochola-Oyier, John Okombo, Leah Mwai, Steven M. Kiara, Lewa Pole, Kevin K. A. Tetteh, Alexis Nzila, and Kevin Marsh
Reference: 
Antimicrob. Agents Chemother. March 2015 vol. 59 no. 3 1770-1775

The mechanisms of drug resistance development in the Plasmodium falciparum parasite to lumefantrine (LUM), commonly used in combination with artemisinin, are still unclear.

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Effects of bed nets and anti-malaria drugs use on childhood mortality in Kenya’s malaria endemic and epidemic areas

February 4, 2015 - 15:12 -- Open Access
Tags: 
Author(s): 
Boniface O K’Oyugi
Reference: 
BMC Public Health 2015, 15:34

This study underscore the need for increasing uptake of malaria interventions and complementing them with longer breastfeeding duration and improved toilet facility in efforts towards reducing infant and child mortality rates in Kenya’s malaria prone areas.

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Perceptions of malaria and acceptance of rapid diagnostic tests and related treatment practises among community members and health care providers in Greater Garissa, North Eastern Province, Kenya

December 22, 2014 - 13:47 -- Open Access
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Author(s): 
Diggle E, Asgary R, Gore-Langton G, Nahashon E, Mungai J, Harrison R, Abagira A, Eves K, Grigoryan Z, Soti D, Juma E, Allan R
Reference: 
Malaria Journal 2014, 13 :502 (17 December 2014)

Gaps in knowledge or incorrect beliefs exist in Greater Garissa and have the potential to act as barriers to complete and correct malaria case management.

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Insecticide-treated net use before and after mass distribution in a fishing community along Lake Victoria, Kenya: successes and unavoidable pitfalls

December 12, 2014 - 06:38 -- Open Access
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Author(s): 
Peter S Larson, Noboru Minakawa, Gabriel O Dida, Sammy M Njenga, Edward L Ionides, Mark L Wilson
Reference: 
Malaria Journal 2014, 13:466 (28 November 2014)

Comprehensive, direct-to-household, mass distribution of ITNs was effective in rapidly scaling up coverage, with use being maintained at a high level at least one year following the intervention.

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Clinical malaria case definition and malaria attributable fraction in the highlands of western Kenya

October 30, 2014 - 16:29 -- Open Access
Author(s): 
Yaw A Afrane, Guofa Zhou, Andrew K Githeko, Guiyun Yan
Reference: 
Malaria Journal 2014, 13:405 (15 October 2014)

To evaluate the effectiveness of malaria interventions, age-specific case definitions of clinical malaria needs to be determined. Cases of clinical malaria through active case surveillance were quantified in a highland area in Kenya and defined clinical malaria for different age groups.

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An assessment of the impact of host polymorphisms on Plasmodium falciparum var gene expression patterns among Kenyan children

October 10, 2014 - 17:40 -- Open Access
Author(s): 
George M Warimwe, Gregory Fegan, Esther W Kiragu, Jennifer N Musyoki, Alexander W Macharia, Kevin Marsh, Thomas N Williams and Peter C Bull
Reference: 
BMC Infectious Diseases 2014, 14:524

Our preliminary findings suggest that host ABO blood group may have a measurable impact on the infecting parasite population. This needs to be verified in larger studies. 

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Impairment of executive function in Kenyan children exposed to severe falciparum malaria with neurological involvement

September 25, 2014 - 12:43 -- Open Access
Author(s): 
Kariuki SM, Abubakar A, Newton CR, Kihara M
Reference: 
Malaria Journal 2014, 13 :365 (16 September 2014)

Linear regression was used to determine the association between neurological phenotypes of severe malaria and executive function performance scores, accounting for potential confounders.

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Longitudinal study on Plasmodium falciparum gametocyte carriage following artemether-lumefantrine administration in a cohort of children aged 12-47 months living in Western Kenya, a high transmission area

July 22, 2014 - 09:03 -- Open Access
Tags: 
Author(s): 
Andagalu B, Mativo J, Kamau E, Ogutu B
Reference: 
Malaria Journal 2014, 13 :265 (9 July 2014)

The treatment of asymptomatic parasitaemic subjects with AL results in a significant reduction in the proportion of subjects who become gametocytaemic for at least 12 weeks.

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