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Nigeria

Congenital Malaria in Calabar, Nigeria: The Molecular Perspective

March 2, 2011 - 12:36 -- Patrick Sampao
Author(s): 
Olabisi A. Oduwole., G. C. Ejezie.,Martin Meremikwu., et al.
Reference: 
Am J Trop Med Hyg, Mar 2011; 84: 386 - 389.

We estimated the prevalence of congenital malaria using nested PCR amplification of the small subunit 18S RNA gene to detect low-level parasitemia and identify Plasmodium species in 204 mother–neonate pairs. Cord-blood parasitemia was detected in four babies by PCR, giving a prevalence of 2.0%.

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Open Access | Improving Rational Treatment of Malaria: Perceptions and Influence of RDTs on Prescribing Behaviour of Health Workers in Southeast Nigeria

February 7, 2011 - 08:08 -- Kabogo Ndegwa
Author(s): 
Benjamin S. C. Uzochukwu, Emmanuel Onwujekwe, Nkoli N. Ezuma, Ogochukwu P. Ezeoke, Miriam O. Ajuba, Florence T. Sibeudu
Reference: 
PLoS ONE 6(1): e14627

RDT-supported malaria diagnosis may have led to the overprescription of ACTs, with the drug being prescribed to people with RDT-negative results.

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Open Access | Cost comparison of microscopy vs empiric treatment for malaria in south-western Nigeria: a prospective study

December 23, 2010 - 14:02 -- Kabogo Ndegwa
Author(s): 
Parikh R, Amole I, Tarpley M, Gbadero D, Davidson M, Vermund SH
Reference: 
Malaria Journal 2010, 9:371 (22 December 2010)

Empiric treatment of all suspected cases of malaria was cheaper (in the end of dry to beginning of rainy season) than only treating those who had microscopy confirmed diagnoses of malaria even though the majority of patients suspected to have malaria were negative via microscopy.

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Efficacy of intermittent preventive treatment with sulfadoxine–pyrimethamine on placental parasitemia in pregnant women in midwestern Nigeria

December 14, 2010 - 08:21 -- Patrick Sampao
Author(s): 
Michael E. Aziken, Kenneth K. Akubuo, Etedafe P. Gharoro
Reference: 
International Journal of Gynecology & Obstetrics, Volume 112, Issue 1, January 2011, Pages 30-33

To assess the effect of intermittent preventive treatment with sulfadoxine and pyrimethamine (IPT-SP) on placental parasitemia and maternal and perinatal outcome.

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Early variations in Plasmodium falciparum dynamics in Nigerian children after treatment with two artemisinin-based combinations: implications on delayed parasite clearance

November 26, 2010 - 09:57 -- Kabogo Ndegwa
Author(s): 
Michael OS, Gbotosho GO, Folarin OA, Okuboyejo T, Sowunmi A, Oduola AM, Happi CT
Reference: 
Malaria Journal 2010, 9:335 (22 November 2010)

The study showed the high efficacy of AL and AA in Nigerian children. In addition the study demonstrated the mobilisation of asexual parasites from the deep to the periphery in the early hours of commencing ACT treatment in a subset of patients in both study groups.

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Open Access | Fine specificity of anti-MSP119 antibodies and multiplicity of Plasmodium falciparum Merozoite Surface Protein 1 types in individuals in Nigeria with sub-microscopic infection

October 22, 2010 - 08:48 -- Kabogo Ndegwa
Author(s): 
Ngoundou-Landji J, Nwuba RI, Anumudu CI, Odaibo AB, Matondo Maya WD, Awobode HO, Okafor CM, Morenikeji OA, Asinobi A, Nwagwu M, Holder AA, Ntoumi F
Reference: 
Malaria Journal 2010, 9:287 (18 October 2010)

In the search for correlates of protection against malaria, which will be essential to evaluate clinical trials of malaria vaccines based on MSP1, this study examines some potential assays and the factors that need to taken into account during their evaluation, using samples from individuals naturally exposed to malaria infection.

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Open Access | Improving quality of malaria treatment services: assessing inequities in consumers' perceptions and providers' behaviour in Nigeria

October 15, 2010 - 14:39 -- Patrick Sampao
Author(s): 
Obinna Onwujekwe, Eric Obikeze , Benjamin Uzochukwu , Ijeoma Okoronkwo and Ogochukwu C Onwujekwe
Reference: 
International Journal for Equity in Health 2010, 9:22

Hence, the study determined the technical and perceived quality of malaria treatment services of different types of providers in three urban and three rural areas in southeast Nigeria.

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Open Access | Short Report: Malaria among antenatal clients attending primary health care facilities in Kano state, Nigeria

August 24, 2010 - 10:08 -- Kabogo Ndegwa
Author(s): 
AU Gajida, Z Iliyasu, AI Zoakah
Reference: 
Annals of African Medicine, Volume : 9 Issue : 3 2010 Page : 188-193

Intermittent Preventive Treatment (IPT) should be provided especially among primigravid, secondigravid and younger mothers at PHC centres.

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Open Access | Poverty and fever vulnerability in Nigeria: a multilevel analysis

August 20, 2010 - 13:19 -- Kabogo Ndegwa
Author(s): 
Yusuf OB, Adeoye BW, Oladepo OO, Peters DH, Bishai D
Reference: 
Malaria Journal 2010, 9:235 (19 August 2010)

While, overall bednet possession was low, less fever was reported in households that possessed bednets. Malaria control strategies and interventions should be designed that will target the poor and make an impact on poverty.

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Open Access | Estimating the Global Clinical Burden of Plasmodium falciparum Malaria in 2007

June 17, 2010 - 15:17 -- Kabogo Ndegwa
Author(s): 
Simon I. Hay, Emelda A. Okiro, Peter W. Gething, Anand P. Patil, Andrew J. Tatem, Carlos A. Guerra, Robert W. Snow
Reference: 
PLoS Med 7(6): e1000290

Cartographic approaches to burden estimation provide a globally consistent measure of malaria morbidity of known fidelity, and they represent the only plausible method in those malaria-endemic countries with nonfunctional national surveillance.

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