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Uganda

Drug seller adherence to clinical protocols with integrated management of malaria, pneumonia and diarrhoea at drug shops in Uganda

July 17, 2015 - 10:04 -- Open Access
Author(s): 
Phyllis Awor, Henry Wamani, Thorkild Tylleskar, Stefan Peterson
Reference: 
Malaria Journal 2015, 14:277 (16 July 2015)

With the introduction of the iCCM intervention at drug shops in Eastern Uganda, it was possible to achieve high adherence to the treatment protocols, which is likely compatible with increased quality of care.

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Forecasting malaria in a highly endemic country using environmental and clinical predictors

June 20, 2015 - 08:13 -- Open Access
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Author(s): 
Kate Zinszer, Ruth Kigozi, Katia Charland, Grant Dorsey, Timothy F Brewer, John S Brownstein, Moses R Kamya, David L Buckeridge
Reference: 
Malaria Journal 2015, 14:245 (18 June 2015)

Clinical data, such as drug treatment, could be used to improve the accuracy of malaria predictions in endemic settings when coupled with environmental predictors.

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NOT Open Access | Impact of Antimalarial Treatment and Chemoprevention on the Drug Sensitivity of Malaria Parasites Isolated from Ugandan Children

May 18, 2015 - 13:05 -- NOT Open Access
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Author(s): 
Patrick Tumwebaze, Melissa D. Conrad, Philip J. Rosenthal, et al.
Reference: 
Antimicrob. Agents Chemother. June 2015 vol. 59 no. 6 3018-3030

Changing treatment practices may be selecting for changes in the drug sensitivity of malaria parasites.

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Impact of rapid diagnostic tests for the diagnosis and treatment of malaria at a peripheral health facility in Western Uganda: an interrupted time series analysis

May 18, 2015 - 12:51 -- Open Access
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Author(s): 
Ross M Boyce, Anthony Muiru, Raquel Reyes, Moses Ntaro, Edgar Mulogo, Michael Matte, Mark J Siedner
Reference: 
Malaria Journal 2015, 14:203 (15 May 2015)

This study is one of the few to demonstrate significant improvement in clinical outcomes and process measures following the introduction of RDTs for the diagnosis of malaria at a rural health facility in Uganda.

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The past, present and future use of epidemiological intelligence to plan malaria vector control and parasite prevention in Uganda

April 20, 2015 - 17:28 -- Open Access
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Author(s): 
Ambrose O Talisuna, Abdisalan M Noor, Albert P Okui, Robert W Snow
Reference: 
Malaria Journal 2015, 14:158 (15 April 2015)

Readily available epidemiological data should become the future business model to maximize malaria funding from 2015.

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Early biting and insecticide resistance in the malaria vector Anopheles might compromise the effectiveness of vector control intervention in Southwestern Uganda

April 15, 2015 - 05:24 -- Open Access
Author(s): 
Ojuka P, Boum Y, Denoeud-Ndam L, Nabasumba C, Muller Y, Okia M, Mwanga-Amumpaire J, Debeaudrap P, Protopopoff N, Etard J
Reference: 
Malaria Journal 2015, 14 :148 (9 April 2015)

Background

Southwestern Uganda has high malaria heterogeneity despite moderate vector control and other interventions. Moreover, the early biting transmission and increased resistance to insecticides might compromise strategies relying on vector control. Consequently, monitoring of vector behaviour and insecticide efficacy is needed to assess the effectiveness of strategies aiming at malaria control. This eventually led to an entomological survey in two villages with high malaria prevalence in this region.

 

Methods

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Promising Perceptions, Divergent Practices and Barriers to Integrated Malaria Prevention in Wakiso District, Uganda: A Mixed Methods Study

April 14, 2015 - 17:40 -- Open Access
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Author(s): 
David Musoke, George Miiro, George Karani, Keith Morris, Simon Kasasa, Rawlance Ndejjo, Jessica Nakiyingi-Miiro, David Guwatudde, Miph Boses Musoke
Reference: 
PLoS ONE 10(4): e0122699

Although knowledge of malaria prevention methods was high and perceptions on the integrated approach promising, practices on integrated malaria prevention was relatively low.

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NOT Open Access | Association between malaria exposure and Kaposi's sarcoma-associated herpes virus seropositivity in Uganda

April 7, 2015 - 10:07 -- NOT Open Access
Author(s): 
Angela Nalwoga, Stephen Cose, Katie Wakeham, Wendell Miley, Juliet Ndibazza, Christopher Drakeley, Alison Elliott, Denise Whitby and Robert Newton
Reference: 
Tropical Medicine & International Health, Volume 20, Issue 5, pages 665–672, May 2015

The association between malaria exposure and KSHV seropositivity suggests that malaria is a cofactor for KSHV infection or reactivation.

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Determinants of malaria diagnostic uptake in the retail sector: qualitative analysis from focus groups in Uganda

March 2, 2015 - 18:45 -- Open Access
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Author(s): 
Jessica Cohen, Alex Cox, William Dickens, Kathleen Maloney, Felix Lam, Günther Fink
Reference: 
Malaria Journal 2015, 14:89 (21 February 2015)

In order to boost demand, these results suggest that private sector RDTs will have to be made convenient and affordable and that targeted behaviour change campaigns should strive to increase the perceived value of diagnosis.

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Prospective validation of pediatric disease severity scores to predict mortality in Ugandan children presenting with malaria and non-malaria febrile illness

February 24, 2015 - 16:37 -- Open Access
Author(s): 
Andrea L Conroy, Michael Hawkes, Kyla Hayford, Sophie Namasopo, Robert O Opoka, Chandy C John, W Conrad Liles and Kevin C Kain
Reference: 
Critical Care 2015, 19:47

We evaluated the ability of three clinical scoring systems to predict in-hospital mortality in a prospective observational study of Ugandan children with fever. We computed the Lambaréné Organ Dysfunction Score (LODS), Signs of Inflammation in Children that Kill (SICK), and the Pediatric Early Death Index for Africa (PEDIA).

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