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Uganda

It could be viral but you don’t know, you have not diagnosed it: health worker challenges in managing non-malaria paediatric fevers in the low transmission area of Mbarara District, Uganda

April 11, 2016 - 16:28 -- Open Access
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Author(s): 
Emily White Johansson, Freddy Eric Kitutu, Chrispus Mayora, Phyllis Awor, Stefan Swartling Peterson, Henry Wamani and Helena Hildenwall
Reference: 
Malaria Journal 2016 15:197, 11 April 2016

Enhanced support is needed to improve RDT adoption at lower level clinics that focuses on empowering providers to successfully manage non-severe, non-malaria paediatric fevers without referral.

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Not Open Access | Frequent Malaria Drives Progressive Vδ2 T-Cell Loss, Dysfunction, and CD16 Up-regulation During Early Childhood

March 31, 2016 - 15:17 -- NOT Open Access
Author(s): 
Lila A. Farrington, Prasanna Jagannathan, Margaret E. Feeney, et al.
Reference: 
J Infect Dis. (2016) 213 (9): 1483-1490.

We observed a progressive attenuation of the Vδ2 response only among children incurring high rates of malaria. Unresponsive Vδ2 T cells were marked by expression of CD16, which was elevated in the setting of high malaria transmission. 

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Factors affecting adherence to national malaria treatment guidelines in management of malaria among public healthcare workers in Kamuli District, Uganda

February 26, 2016 - 17:11 -- Open Access
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Author(s): 
Charles Bawate, Sylvia T. Callender-Carter, Ben Nsajju and Denis Bwayo
Reference: 
Malaria Journal 2016 15:112, 24 February 2016

Adherence to malaria treatment guidelines in Uganda is sub-optimal.

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Timing of malaria in pregnancy and impact on infant growth and morbidity: a cohort study in Uganda

February 18, 2016 - 09:45 -- Open Access
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Author(s): 
Pierre De Beaudrap, Eleanor Turyakira, Carolyn Nabasumba, Benon Tumwebaze, Patrice Piola, Yap Boum II and Rose McGready
Reference: 
Malaria Journal 2016 15:92, 16 February 2016

This study shows that despite frequent active screening and prompt treatment of MiP, impaired growth and an increased risk of malaria and non-malaria infections can be observed in the infants.

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Endothelial activation, haemostasis and thrombosis biomarkers in Ugandan children with severe malaria participating in a clinical trial

February 8, 2016 - 17:10 -- Open Access
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Author(s): 
Susan M. Graham, Junmei Chen, W. Conrad Liles, et al.
Reference: 
Malaria Journal 2016 15:56, 2 February 2016

These results confirm that severe malaria is associated with endothelial activation, and suggest that endothelial activation contributes to microvascular thrombosis and endothelial damage.

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Ecological Drivers of Mansonella perstans Infection in Uganda and Patterns of Co-endemicity with Lymphatic Filariasis and Malaria

February 8, 2016 - 16:54 -- Open Access
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Author(s): 
Anna-Sofie Stensgaard, Penelope Vounatsou, Ambrose W. Onapa, Jürg Utzinger, Erling M. Pedersen, Thomas K. Kristensen, Paul E. Simonsen
Reference: 
PLoS Negl Trop Dis 10(1): e0004319

This study presents the first geostatistical risk map for M. perstans in Uganda.

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What drives the consistent use of long-lasting insecticidal nets over time? A multi-method qualitative study in mid-western Uganda

February 2, 2016 - 18:53 -- Open Access
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Author(s): 
Clare E. Strachan, Anthony Nuwa, Denis Muhangi, Albert P. Okui, Michelle E. H. Helinski and James K. Tibenderana
Reference: 
Malaria Journal 2016 15:44, 28 January 2016

A multitude of interplaying factors encouraged consistent LLIN use in this setting.

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Why do health workers give anti-malarials to patients with negative rapid test results? A qualitative study at rural health facilities in western Uganda

January 12, 2016 - 17:25 -- Open Access
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Author(s): 
Robin Altaras, Anthony Nuwa, Bosco Agaba, Elizabeth Streat, James Tibenderana, Clare Strachan
Reference: 
Malaria Journal 2016, 15:23 (11 January 2016)

The study found high provider adherence to RDT results, but that providers believed in certain clinical exceptions and felt they lacked alternative options.

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Estimating malaria parasite prevalence from community surveys in Uganda: a comparison of microscopy, rapid diagnostic tests and polymerase chain reaction

January 7, 2016 - 15:55 -- Open Access
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Author(s): 
Joaniter Nankabirwa, Adoke Yeka, Emmanuel Arinaitwe, Ruth Kigozi, Chris Drakeley, Moses Kamya, Bryan Greenhouse, Philip Rosenthal, Grant Dorsey, Sarah Staedke
Reference: 
Malaria Journal 2015, 14:528 (30 December 2015)

Malaria prevalence estimates varied with diagnostic test, age, and transmission intensity.

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