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Uganda

Intermittent preventive treatment for malaria among children in a refugee camp in Northern Uganda: lessons learned

May 25, 2017 - 14:35 -- Open Access
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Author(s): 
Matthew E. Coldiron, Estrella Lasry, Rebecca F. Grais, et al.
Reference: 
Malaria Journal 2017 16:218, 23 May 2017

Northern Uganda hosts a large population of refugees from South Sudan, and malaria is one of the major health problems in the area.

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Comparison of the capacity between public and private health facilities to manage under-five children with febrile illnesses in Uganda

May 9, 2017 - 15:44 -- Open Access
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Author(s): 
Esther Buregyeya, Elizeus Rutebemberwa, Phillip LaRussa, Sham Lal, Sîan E. Clarke, Kristian S. Hansen, Pascal Magnussen and Anthony K. Mbonye
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Malaria Journal 2017 16:183, 2 May 2017

Deficiencies of equipment, supplies and training exist even in public health facilities.

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Travel and the emergence of high-level drug resistance in Plasmodium falciparum in southwest Uganda: results from a population-based study

April 18, 2017 - 15:33 -- Open Access
Author(s): 
Caroline A. Lynch, Richard Pearce, Hirva Pota, Connie Egwang, Thomas Egwang, Amit Bhasin, Jonathan Cox, Tarekegn A. Abeku and Cally Roper
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Malaria Journal 2017 16:150, 17 April 2017

There is sustained local transmission of parasites with the dhfr I164L mutation in Rukungiri and no evidence to indicate its occurrence is associated with recent travel to highly resistant neighbouring areas.

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The impact of an intervention to introduce malaria rapid diagnostic tests on fever case management in a high transmission setting in Uganda: A mixed-methods cluster-randomized trial (PRIME)

April 12, 2017 - 15:48 -- Open Access
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Author(s): 
Clare I. R. Chandler, Emily L. Webb, Sarah G. Staedke, et al.
Reference: 
PLoS ONE 12(3): e0170998

The PRIME intervention did not have the desired impact on inappropriate treatment of malaria for children under five.

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Disparities between malaria infection and treatment rates: Evidence from a cross-sectional analysis of households in Uganda

March 30, 2017 - 16:27 -- Open Access
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Author(s): 
Indrani Saran, Jessica Cohen
Reference: 
PLoS ONE 12(2): e0171835

Our findings suggest that households have significant mis-perceptions about malaria likelihood that may contribute to the under-treatment of malaria.

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Drug resistance mediating Plasmodium falciparum polymorphisms and clinical presentations of parasitaemic children in Uganda

March 28, 2017 - 15:11 -- Open Access
Author(s): 
Stephen Tukwasibwe, Patrick Tumwebaze, Melissa Conrad, Emmanuel Arinaitwe, Moses R. Kamya, Grant Dorsey, Samuel L. Nsobya, Bryan Greenhouse and Philip J. Rosenthal
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Malaria Journal 2017 16:125, 21 March 2017

Although infections with only the mutant pfmdr1 86Y genotype were associated with symptomatic infection, this association could primarily be explained by greater parasite densities and therefore greater prevalence of mixed infections in symptomatic children.

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Age and geographic patterns of Plasmodium falciparum malaria infection in a representative sample of children living in Burkitt lymphoma-endemic areas of northern Uganda

March 22, 2017 - 15:23 -- Open Access
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Author(s): 
Marlena Maziarz, Tobias Kinyera, Sam M. Mbulaiteye, et al.
Reference: 
Malaria Journal 2017 16:124, 20 March 2017

The study observed high but geographically and demographically heterogenous patterns of asymptomatic malaria prevalence among children living in northern Uganda.

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Avidity of anti-malarial antibodies inversely related to transmission intensity at three sites in Uganda

February 15, 2017 - 15:23 -- Open Access
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Author(s): 
Isaac Ssewanyana, Emmanuel Arinaitwe, Kevin K. A. Tetteh, et al.
Reference: 
Malaria Journal 2017 16:67, 10 February 2017

Avidity to two different P. falciparum antigens was lower in areas of high transmission intensity compared to areas with lower transmission.

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Absence of in vivo selection for K13 mutations after artemether–lumefantrine treatment in Uganda

January 14, 2017 - 16:17 -- Open Access
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Author(s): 
Betty Balikagala, Toshihiro Mita, Takafumi Tsuboi, et al.
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Malaria Journal 2017 16:23, 9 January 2017

Mutations in pfkelch13 and the six background genes may not play an important role in the in vivo selection after artemether–lumefantrine treatment in Uganda.

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Assessing the effect of indoor residual spraying (IRS) on malaria morbidity in Northern Uganda: a before and after study

January 7, 2017 - 14:32 -- Open Access
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Author(s): 
Betty Bawuba Tukei, Andy Beke and Héctor Lamadrid-Figueroa
Reference: 
Malaria Journal 2017 16:4, 3 January 2017

The study results show that IRS was associated with a significant reduction in malaria morbidity in northern Uganda in the first 3 months following IRS.

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