The incidence of malaria during term pregnancy was unexpectedly low, but still increased severe fetal and neonatal complications, thus advocating the administration of at least three doses of SMP, started before the 20th week of pregnancy.
This study showed that antibody responses against MSP-119 vary considerably in children from the different bioecological strata in Cameroon and could be linked to the differential exposure to malaria in the different strata.
These results highlight the increasing spread of insecticide resistance and the challenges that control programmes face to maintain the continued effectiveness of insecticide-based interventions.
Timing of the malaria survey influences estimates of the geographical distribution of disease risk, especially in settings with seasonal transmission.
A high proportion of IgG responders was observed in this study, suggesting a high degree exposure of the target population to malaria parasites.
Plasmodium falciparum malaria parasite densities do not differ between capillary and venous blood in asymptomatic subjects for both gametocyte and trophozoite stages.
Even though the proportion of chloroquine-sensitive parasites seems to be increasing in southeastern Cameroon, a reintroduction of chloroquine cannot be recommended at present in Cameroon.
Women in Cameroon and their antenatal providers missed many opportunities to prevent malaria in pregnancy.
These findings pinpoint the need for more frequent replacement of LLINs especially for people with low SES and also the need for the promotion of good practices on the maintenance and washing of nets.
Artesunate is a cost effective malaria treatment option relative to quinine alternatives with the lowest incremental cost per unit of effectiveness.