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Stable malaria incidence despite scaling up control strategies in a malaria vaccine-testing site in Mali

September 25, 2014 - 12:40 -- Open Access
Author(s): 
Coulibaly D, Travassos MA, Thera MA, et al.
Reference: 
Malaria Journal 2014, 13 :374 (19 September 2014)

To document malaria incidence, a cohort of 400 children aged 0 to 14 years was followed for three to four years up to July 2013. Monthly cross-sectional surveys were done to measure the prevalence of malaria infection and anaemia.

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Glucose-6-phosphate dehydrogenase polymorphisms and susceptibility to mild malaria in dogon and Fulani, Mali

July 22, 2014 - 09:15 -- Open Access
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Author(s): 
Maiga B, Dolo A, Campino S, Sepulveda N, Corran P, Rockett KA, Troye-Blomberg M, Doumbo OK, Clark TG
Reference: 
Malaria Journal 2014, 13 :270 (11 July 2014)

The results highlight the need to consider markers in addition to G6PD202 in studies of deficiency.

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Haptoglobin phenotype prevalence and cytokine profiles during Plasmodium falciparum infection in Dogon and Fulani ethnic groups living in Mali

December 3, 2013 - 10:44 -- Open Access
Author(s): 
Perdijk O, Arama C, Giusti P, Maiga B, Troye-Blomberg M, Dolo A, Doumbo O, Persson J, Boström S
Reference: 
Malaria Journal 2013, 12 :432 (25 November 2013)
MalariaWorld

Ethnicity might be an important confounder on the Hp phenotype-dependent susceptibility to malaria and future studies could consider taking this into account when designing new immunological studies.

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Plasmodium falciparum Clearance Rates in Response to Artesunate in Malian Children With Malaria: Effect of Acquired Immunity

May 6, 2013 - 17:04 -- Open Access
Author(s): 
Tatiana M. Lopera-Mesa., Saibou Doumbia., Serena Chiang, Amir E., Rick M. Fairhurst., et al
Reference: 
J Infect Dis. (2013) 207 (11):1664-1674.
MalariaWorld

 

We estimated half-life by measuring parasite density every 6 hours until undetectable and evaluated the effects of age, sex, ethnicity, and red blood cell (RBC) polymorphisms on half-life. We quantified the proportion of parasitized RBCs recognized by autologous immunoglobulin G (IgG).

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Spatio-temporal analysis of malaria within a transmission season in Bandiagara, Mali

March 7, 2013 - 07:22 -- Open Access
Author(s): 
Coulibaly D, Rebaudet S, Doumbo OK, et al.
Reference: 
Malaria Journal 2013, 12:82 (1 March 2013)
MalariaWorld

These results confirm the existence of a marked spatial heterogeneity of malaria transmission in Bandiagara, providing support for implementation of targeted interventions.

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Not Open Access | Quinine Treatment Selects the pfnhe–1 ms4760–1 Polymorphism in Malian Patients with Falciparum Malaria

January 9, 2013 - 15:57 -- NOT Open Access
Author(s): 
Aminatou Kone, Jianbing Mu, Hamma Maiga, Abdoulaye A. Djimde, et al.
Reference: 
J Infect Dis. (2013) 207 (3): 520-527
MalariaWorld

This study supports a role for pfnhe–1 in decreased susceptibility of P. falciparum to quinine in the field.

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Plasmodium vivax malaria in Mali: a study from three different regions

December 6, 2012 - 09:01 -- Open Access
Author(s): 
Bernabeu M, Gomez-Perez GP, Sissoko S, Niambélé MB, Haibala AA, Sanz A, Théra MA, Fernandez-Becerra C, Traoré K, Alonso PL, Bassat Q, Portillo HA, Doumbo O
Reference: 
Malaria Journal 2012, 11:405 (5 December 2012)
MalariaWorld

The diagnostics of this human malaria parasite should be taken into account in the context of malaria control and elimination efforts, not only in Mali, but also in sub-Saharan Africa.

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Filariasis Attenuates Anemia and Proinflammatory Responses Associated with Clinical Malaria: A Matched Prospective Study in Children and Young Adults

November 12, 2012 - 07:57 -- Open Access
Author(s): 
Housseini Dolo, Yaya I. Coulibaly, Amy D. Klion, et al.
Reference: 
PLoS Negl Trop Dis 6(11): e1890
MalariaWorld

These data suggest that pre-existent filarial infection attenuates immune responses associated with severe malaria and protects against anemia, but has little effect on susceptibility to or severity of acute malaria infection.

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Not Open Access | Hidden costs: The direct and indirect impact of user fees on access to malaria treatment and primary care in Mali

September 18, 2012 - 17:16 -- Patrick Sampao
Author(s): 
Ari Johnson, Adeline Goss, Jessica Beckerman, Arachu Castro
Reference: 
Social Science & Medicine, Volume 75, Issue 10, November 2012, Pages 1786-1792

MalariaWorldThis ethnographic study aims to identify consequences of user fees on gender inequality, food insecurity, and household decision-making for a group of women living in poverty.

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NOT Open Access | P005 Cellular responses to repeated malaria episodes: Does the concept of original antigenic sin apply to Plasmodium falciparum malaria?

August 16, 2012 - 08:15 -- Kabogo Ndegwa
Author(s): 
B. Seyoum Alemu, A. Famanta, S. Doumbia, S. Samake, B. Traore, J. Duan, I. Zaidi, R.M. Fairhurst, C.A. Long, P.E. Duffy, M. Diakite, M. Walther
Reference: 
Cytokine, Volume 59, Issue 3, September 2012, Pages 520

MalariaWorldThe results of this study will enable us to determine whether original antigenic sin influences malaria incidence, and may reveal an association between a specific immunological response pattern and enhanced protection from a subsequent malaria episode, which can be further explored in identifying candidate vaccine antigens.

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