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New Guinea

NOT Open Access | Pharmacokinetic Comparison of Two Piperaquine-Containing Artemisinin Combination Therapies in Papua New Guinean Children with Uncomplicated Malaria

May 15, 2012 - 12:02 -- Kabogo Ndegwa
Author(s): 
Sam Salman, Madhu Page-Sharp, Kevin T. Batty, Kaye Kose, Susan Griffin, Peter M. Siba, Kenneth F. Ilett, Ivo Mueller, and Timothy M. E. Davis
Reference: 
Antimicrob. Agents Chemother. June 2012 vol. 56 no. 6 3288-3297

MalariaWorldPharmacokinetic differences between piperaquine (PQ) base and PQ tetraphosphate were investigated in 34 Papua New Guinean children aged 5 to 10 years treated for uncomplicated malaria with artemisinin-PQ (ART-PQ) base or dihydroartemisinin-PQ (DHA-PQ) tetraphosphate.

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