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Papua New Guinea

Long-term acceptability, durability and bio-efficacy of ZeroVector® durable lining for vector control in Papua New Guinea

March 2, 2017 - 15:33 -- Open Access
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Author(s): 
Joseph J. Kuadima, Lincoln Timinao, Laura Naidi, Anthony Tandrapah, Manuel W. Hetzel, Cyrille Czeher and Justin Pulford
Reference: 
Malaria Journal 2017 16:93, 28 February 2017

The ZeroVector® DL installation remained highly acceptable at 36-months post-installation, the material and fixtures proved durable and the efficacy against malaria vectors did not decrease.

Effects of Plasmodium falciparum infection on umbilical artery resistance and intrafetal blood flow distribution: a Doppler ultrasound study from Papua New Guinea

January 24, 2017 - 18:02 -- Open Access
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Author(s): 
Maria Ome-Kaius, Stephan Karl, Regina Alice Wangnapi, John Walpe Bolnga, Glen Mola, Jane Walker, Ivo Mueller, Holger Werner Unger and Stephen John Rogerson
Reference: 
Malaria Journal 2017 16:35, 19 January 2017

Both microscopic and sub-microscopic P. falciparum infections impair fetoplacental and intrafetal flow, at least temporarily.

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Changes in malaria burden and transmission in sentinel sites after the roll-out of long-lasting insecticidal nets in Papua New Guinea

June 16, 2016 - 15:04 -- Open Access
Author(s): 
Hetzel M, Reimer L, Gideon G, Koimbu G, Barnadas C, Makita L, Siba P, Mueller I
Reference: 
Parasites & Vectors 2016, 9:340 (14 June 2016)

This manuscript assesses changes in malaria prevalence, incidence and transmission in sentinel sites following the first national distribution of long-lasting insecticidal nets (LLINs).

NOT Open Access | Risk factors for Plasmodium falciparum and Plasmodium vivax gametocyte carriage in Papua New Guinean children with uncomplicated malaria

June 1, 2016 - 14:46 -- NOT Open Access
Author(s): 
Stephan Karl, Moses Laman, Timothy M.E. Davis, et al.
Reference: 
Acta Tropica Volume 160, August 2016, Pages 1–8

There are limited data on gametocytaemia risk factors before/after treatment with artemisinin combination therapy in children from areas with transmission of multiple Plasmodium species.

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Medical Treatment: 

Strategies for Understanding and Reducing the Plasmodium vivax and Plasmodium ovale Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model

October 29, 2015 - 05:58 -- Open Access
Author(s): 
Leanne J. Robinson, Rahel Wampfler, Ivo Mueller, et al.
Reference: 
PLoS Med 12(10): e1001891

These results suggest that relapses cause approximately four of every five P. vivax infections and at least three of every five P. ovale infections in PNG children and are important in sustaining transmission.

Medical Treatment: 

Accuracy of an HRP-2/panLDH rapid diagnostic test to detect peripheral and placental Plasmodium falciparum infection in Papua New Guinean women with anaemia or suspected malaria

October 20, 2015 - 09:11 -- Open Access
Author(s): 
Alexandra Umbers, Holger Unger, Ivo Mueller, et al.
Reference: 
Malaria Journal 2015, 14:412 (19 October 2015)

In PNG, HRP-2/pLDH RDTs may be useful to diagnose peripheral P. falciparum infections in symptomatic pregnant women.

Significant geographical differences in prevalence of mutations associated with Plasmodium falciparum and Plasmodium vivax drug resistance in two regions from Papua New Guinea

October 14, 2015 - 06:47 -- Open Access
Author(s): 
Céline Barnadas, Lincoln Timinao, Ivo Mueller, et al.
Reference: 
Malaria Journal 2015, 14:399 (9 October 2015)

This LDR-FMA multiplex platform shows feasibility for low-cost, high-throughput, rapid characterization of a broad range of drug-resistance markers in low parasitaemia infections.

Blood-Stage Parasitaemia and Age Determine Plasmodium falciparum and P. vivax Gametocytaemia in Papua New Guinea

June 2, 2015 - 13:48 -- Open Access
Author(s): 
Cristian Koepfli, Leanne J. Robinson, Ivo Mueller, et al.
Reference: 
PLoS ONE 10(5): e0126747

A better understanding of human-to-mosquito transmission is crucial to control malaria.

Malaria preventive therapy in pregnancy and its potential impact on immunity to malaria in an area of declining transmission

May 30, 2015 - 10:30 -- Open Access
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Author(s): 
Andrew Teo, Wina Hasang, Louise Randall, Holger Unger, Peter Siba, Ivo Mueller, Graham Brown, Stephen Rogerson
Reference: 
Malaria Journal 2015, 14:215 (26 May 2015)

Different preventive anti-malarial chemotherapy regimens used during pregnancy had limited impact on malarial-immunity in a low-transmission region of Papua New Guinea.

Artemether-lumefantrine versus artemisinin-naphthoquine in Papua New Guinean children with uncomplicated malaria: a six months post-treatment follow-up study

March 23, 2015 - 12:09 -- Open Access
Author(s): 
Moses Laman, John M Benjamin, Brioni R Moore, Mary Salib, Somoyang Tawat, Wendy A Davis, Peter M Siba, Leanne J Robinson, Timothy Davis
Reference: 
Malaria Journal 2015, 14:121 (21 March 2015)

The greater effectiveness of artemisinin-NQ over conventional AM-LM extends to at least six months post-treatment for clinical malaria but not non-malarial illness.

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