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Tumour necrosis factor allele variants and their association with the occurrence and severity of malaria in African children: a longitudinal study

June 20, 2015 - 10:14 -- Open Access
Wanjiku N Gichohi-Wainaina, Alida Melse-Boonstra, Edith J Feskens, Ayse Y Demir, Jacobien Veenemans, Hans Verhoef
Malaria Journal 2015, 14:249 (20 June 2015)

In this cohort of Tanzanian children, the TNF−1031 CC genotype was associated with increased rates of malarial episodes, whereas the TNF−308 AA genotype was associated with decreased rates.

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Open Access | Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children

December 3, 2010 - 06:01 -- Kabogo Ndegwa
John Lusingu, Ally Olotu, Lorenz von Seidlein, et al.
PLoS ONE 5(11): e14090

The malaria vaccine candidate, RTS,S/AS01E, showed promising protective efficacy in a trial of Kenyan and Tanzanian children aged 5 to 17 months. Here we report on the vaccine's safety and tolerability.

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