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Brazilian Amazon

IL10A genotypic association with decreased IL-10 circulating levels in malaria infected individuals from endemic area of the Brazilian Amazon

February 24, 2015 - 16:03 -- Open Access
Virginia A Pereira, Juan C Sánchez-Arcila, Joseli Oliveira-Ferreira, et al.
Malaria Journal 2015, 14:30 (28 January 2015)

This study shows that the IL10A-592A/C and IL10A-819 T/C polymorphisms were associated with malaria and decreased IL-10 levels and low parasite density suggesting that this polymorphism influence IL-10 levels and may influence in the susceptibility to clinical malaria.

Not Open Access | Naturally acquired antibodies to Plasmodium vivax blood-stage vaccine candidates (PvMSP-119 and PvMSP-3α359−798) and their relationship with hematological features in malaria patients from the Brazilian Amazon

July 2, 2012 - 13:26 -- Patrick Sampao
Luiza Carvalho Mourão, Cristiane Guimarães Morais, Érika Martins Braga, et al.
Microbes and Infection, Volume 14, Issue 9, August 2012, Pages 730-739

MalariaWorldWe investigated specific antibody responses against two Plasmodium vivax vaccine candidates, PvMSP-119 and PvMSP-3α359−798. Moreover, we assessed the relationship between these antibodies and morbidity parameters.

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Open Access | Hepatitis B Infection Is Associated with Asymptomatic Malaria in the Brazilian Amazon

June 1, 2011 - 08:01 -- Patrick Sampao
Bruno B. Andrade, Cristiane J. N. Santos, Manoel Barral-Netto, et al.
PLoS ONE 6(5): e19841.

This study aimed to address this question. Methodology and Findings An observational study of 636 individuals was performed in Rondônia, western Amazon, Brazil between 2006 and 2007.

B cell epitope mapping and characterization of naturally acquired antibodies to the Plasmodium vivax Merozoite Surface Protein-3α (PvMSP-3α) in malaria exposed individuals from Brazilian Amazon

February 7, 2011 - 09:12 -- Patrick Sampao
J.C. Lima-Junior., J. Jiang., Oliveira-Ferreira., et al
Vaccine, Volume 29, Issue 9, 17 February 2011, Pages 1801-1811

Our results indicates that PvMSP3 is highly immunogenic in naturally exposed populations, where 78% of studied individuals present IgG immune response against the full-length recombinant protein (PVMSP3-FL) and IgG subclass profile was similar to all five recombinant proteins studied with a high predominance of IgG1 and IgG3.

Open Access | Dispatch: Severe Plasmodium vivax Malaria, Brazilian Amazon

September 24, 2010 - 08:43 -- Patrick Sampao
Márcia A., Cynthia O., et al
Emerging Infectious Diseases, Volume 16, Number 10–October 2010

These data help characterize the clinical profile of severe P. vivax malaria in Latin America.

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