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Brazilian Amazon

IL10A genotypic association with decreased IL-10 circulating levels in malaria infected individuals from endemic area of the Brazilian Amazon

February 24, 2015 - 16:03 -- Open Access
Author(s): 
Virginia A Pereira, Juan C Sánchez-Arcila, Joseli Oliveira-Ferreira, et al.
Reference: 
Malaria Journal 2015, 14:30 (28 January 2015)

This study shows that the IL10A-592A/C and IL10A-819 T/C polymorphisms were associated with malaria and decreased IL-10 levels and low parasite density suggesting that this polymorphism influence IL-10 levels and may influence in the susceptibility to clinical malaria.

Not Open Access | Naturally acquired antibodies to Plasmodium vivax blood-stage vaccine candidates (PvMSP-119 and PvMSP-3α359−798) and their relationship with hematological features in malaria patients from the Brazilian Amazon

July 2, 2012 - 13:26 -- Patrick Sampao
Author(s): 
Luiza Carvalho Mourão, Cristiane Guimarães Morais, Érika Martins Braga, et al.
Reference: 
Microbes and Infection, Volume 14, Issue 9, August 2012, Pages 730-739

MalariaWorldWe investigated specific antibody responses against two Plasmodium vivax vaccine candidates, PvMSP-119 and PvMSP-3α359−798. Moreover, we assessed the relationship between these antibodies and morbidity parameters.

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Open Access | Hepatitis B Infection Is Associated with Asymptomatic Malaria in the Brazilian Amazon

June 1, 2011 - 08:01 -- Patrick Sampao
Author(s): 
Bruno B. Andrade, Cristiane J. N. Santos, Manoel Barral-Netto, et al.
Reference: 
PLoS ONE 6(5): e19841.

This study aimed to address this question. Methodology and Findings An observational study of 636 individuals was performed in Rondônia, western Amazon, Brazil between 2006 and 2007.

B cell epitope mapping and characterization of naturally acquired antibodies to the Plasmodium vivax Merozoite Surface Protein-3α (PvMSP-3α) in malaria exposed individuals from Brazilian Amazon

February 7, 2011 - 09:12 -- Patrick Sampao
Author(s): 
J.C. Lima-Junior., J. Jiang., Oliveira-Ferreira., et al
Reference: 
Vaccine, Volume 29, Issue 9, 17 February 2011, Pages 1801-1811

Our results indicates that PvMSP3 is highly immunogenic in naturally exposed populations, where 78% of studied individuals present IgG immune response against the full-length recombinant protein (PVMSP3-FL) and IgG subclass profile was similar to all five recombinant proteins studied with a high predominance of IgG1 and IgG3.

Open Access | Dispatch: Severe Plasmodium vivax Malaria, Brazilian Amazon

September 24, 2010 - 08:43 -- Patrick Sampao
Author(s): 
Márcia A., Cynthia O., et al
Reference: 
Emerging Infectious Diseases, Volume 16, Number 10–October 2010

These data help characterize the clinical profile of severe P. vivax malaria in Latin America.

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