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An Outbreak of Plasmodium falciparum Malaria in U.S. Marines Deployed to Liberia

August 5, 2010 - 15:06 -- Patrick Sampao
Author(s): 
Timothy J., Philip E., et al.
Reference: 
Am J Trop Med Hyg, Aug 2010; 83: 258 - 265.

An outbreak investigation showed that only 19 (45%) used insect repellent, 5 (12%) used permethrin-treated clothing, and none used bed netting. Adherence with weekly mefloquine (MQ) was reported by 23 (55%). However, only 4 (10%) had serum MQ levels high enough to correlate with protection (> 794 ng/mL), and 9 (22%) had evidence of steady-state kinetics (MQ carboxy metabolite/MQ > 3.79).

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