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Brazil

Open Access | Deforestation and Malaria in Mâncio Lima County, Brazil

June 24, 2010 - 09:54 -- Patrick Sampao
Author(s): 
Sarah H. Olson, Comments to Author Ronald Gangnon, Guilherme Abbad Silveira, and Jonathan A. Patz
Reference: 
Emerging Infectious Diseases, Volume 16, Number 7–July 2010

Our cross-sectional study shows malaria incidence across health districts in 2006 is positively associated with greater changes in percentage of cumulative deforestation within respective health districts.

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Tools, tools, tools...but what about strategy?

May 30, 2010 - 11:26 -- Bart G.J. Knols

As part of the TH!NK3 blogging competition 'Developing World', I wrote an article last week titled 'The man who saved Brazil'. It was the 11th article I wrote for this endeavour, and I see it as my most important one till now. It is the one I sincerely hope you will read. And let me know how you feel about it.

Open Access | Complete mtDNA genomes of Anopheles darlingi and an approach to anopheline divergence time

May 17, 2010 - 09:28 -- Kabogo Ndegwa
Author(s): 
Moreno M, Marinotti O, Krzywinski J, Tadei WP, James AA, Achee NL, Conn JE
Reference: 
Malaria Journal 2010, 9:127 (14 May 2010)

Analyses of mtDNA genomes of Anopheles darlingi do not provide support for speciation in the taxon. The dates estimated for divergence among the anopheline groups tested is in agreement with the geological split of western Gondwana (95 mya), and provides additional support for explaining the absence of Cellia in the New World, and Nyssorhynchus in the Afro-Eurasian continents.

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Open Access | Towards a precise test for malaria diagnosis in the Brazilian Amazon: comparison among field microscopy, a rapid diagnostic test, nested PCR, and a computational expert system based on artificial neural networks

May 7, 2010 - 07:00 -- Kabogo Ndegwa
Author(s): 
Andrade BB, Reis-Filho A, Barros AM, Souza-Neto SM, Nogueira LL, Fukutani KF, Camargo EP, Camargo LM, Barral A, Duarte A, Barral-Netto M
Reference: 
Malaria Journal 2010, 9:117 (6 May 2010)

An RDT for malaria diagnosis may find a promising use in the Brazilian Amazon integrating a rational diagnostic approach. Despite the low performance of the MalDANN test using solely epidemiological data, an approach based on neural networks may be feasible in cases where simpler methods for discriminating individuals below and above threshold cytokine levels are available.

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Open Access | Review: Malaria in Brazil: an overview

May 3, 2010 - 09:36 -- Kabogo Ndegwa
Author(s): 
Oliveira-Ferreira J, Lacerda MV, Brasil P, Ladislau JL, Tauil PL, Daniel-Ribeiro CT
Reference: 
Malaria Journal 2010, 9:115 (30 April 2010)

Malaria is still a major public health problem in Brazil, with approximately 306,000 registered cases in 2009, but it is estimated that in the early 1940s, around six million cases of malaria occurred each year.

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Open Access | Estimation of divergence time between two sibling species of the Anopheles (Kerteszia) cruzii complex using a multilocus approach

April 29, 2010 - 14:46 -- Patrick Sampao
Author(s): 
Luísa DP Rona, Carlos J Carvalho-Pinto, Camila J Mazzoni, and Alexandre A Peixoto
Reference: 
BMC Evolutionary Biology 2010, 10:91

The analysis revealed very high FST values and fixed differences between the two An. cruzii sibling species in all loci, irrespective of their function. An Isolation with Migration model was fit to the data using the IM program.

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Epidemiology and control of frontier malaria in Brazil: lessons from community-based studies in rural Amazonia

April 16, 2010 - 09:58 -- Patrick Sampao
Author(s): 
Natal S. S., M. da Silva-N., et al.
Reference: 
Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 104, Issue 5, May 2010, Pages 343-350

We analysed the incidence of slide-confirmed symptomatic infections diagnosed between 2001 and 2006 in a cohort of 531 individuals (2281.53 person-years of follow-up) and parasite prevalence data derived from four cross-sectional surveys.

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Open Access | FY polymorphisms and vivax malaria in inhabitants of Amazonas State, Brazil

April 7, 2010 - 11:43 -- Kabogo Ndegwa
Author(s): 
Sérgio Roberto Lopes Albuquerque, Francimary de Oliveira Cavalcante, Edalton Cesar Sanguino, Lucianna Tezza, Fernanda Chacon, Lilian Castilho and Maria Cristina dos Santos
Reference: 
Parasitology Research, Volume 106, Number 5 April, 2010

These results suggest that natural adaptations, in malaria-endemic regions, could be leading to the arising of partial defense mechanisms against P. vivax, which is different from the previously described in African descents, as well as adaptations that could be increasing the susceptibility of human to this kind of malaria.

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Naturally Acquired Antibodies to Plasmodium vivax Duffy Binding Protein (DBP) in Rural Brazilian Amazon

February 10, 2010 - 13:38 -- Ingeborg van Schayk
Author(s): 
Flávia A. Souza-Silva, Mônica da Silva-Nunes, Bruno A. M. Sanchez, Isabela P. Ceravolo, Rosely S. Malafronte, Cristiana F. A. Brito, Marcelo U. Ferreira, AND Luzia H. Carvalho
Reference: 
Am J Trop Med Hyg 2010;82 185-193

Duffy binding protein (DBP), a leading malaria vaccine candidate, plays a critical role in Plasmodium vivax erythrocyte invasion. Sixty-eight of 366 (18.6%) subjects had IgG anti-DBP antibodies by enzyme-linked immunosorbent assay (ELISA) in a community-based cross-sectional survey in the Brazilian Amazon Basin.

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Open Access | Molecular evidence for the occurrence of a new sibling species within the Anopheles (Kerteszia) cruzii complex in south-east Brazil

January 29, 2010 - 15:00 -- Ingeborg van Schayk
Author(s): 
Luisa DP Rona, Carlos J Carvalho-Pinto, Alexandre A Peixoto
Reference: 
Malaria Journal 2010, 9:33 (26 January 2010)

Preliminary work presenting genetic differentiation for two populations of that species from the same Brazilian locality. It shows promising results as both gene markers and the different analyses used present a consistent trend towards the separation into two taxa.

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