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Brazil

Column: Sleepless in the liver: would revisiting the past give any directions on how to deal with hypnozoite carriers of P. vivax?

February 6, 2014 - 20:51 -- Bart G.J. Knols
Many of the recent strategies to improve malaria control have been focusing on improving the detection of very low parasitaemias to identify asymptomatic carriers of Plasmodium sp. to reduce the infective reservoir. Although these strategies are extremely rational and sensible to tackle most of malaria infections, they will probably not be sufficient to achieve elimination for parasites that present relapses, as is the case for Plasmodium vivax. The need to look for new and sophisticated methods has been exhaustively stressed by researchers, however, at this time, revisiting a simple and efficient strategy successfully employed in the past could prove to be a path to be followed...

Geographic information systems and logistic regression for high-resolution malaria risk mapping in a rural settlement of the southern Brazilian Amazon

November 25, 2013 - 12:26 -- Open Access
Author(s): 
de Oliveira EC, dos Santos ES, Zeilhofer P, Souza-Santos R, Atanaka-Santos M
Reference: 
Malaria Journal 2013, 12 :420 (15 November 2013)
MalariaWorld

Mid-resolution, remote sensing data and GIS-derived distance measures can be successfully combined with digital maps of the housing location of (non-) infected inhabitants to predict relative likelihood of disease infection through the analysis by logistic regression.

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Improving the Modeling of Disease Data from the Government Surveillance System: A Case Study on Malaria in the Brazilian Amazon

November 13, 2013 - 07:24 -- Open Access
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Author(s): 
Denis Valle, James Clark
Reference: 
PLoS Comput Biol 9(11): e1003312
MalariaWorld

The study of the effect of large-scale drivers (e.g., climate) of human diseases typically relies on aggregate disease data collected by the government surveillance network.

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Evidence for the occurrence of two sympatric sibling species within the Anopheles (Kerteszia) cruzii complex in southeast Brazil and the detection of asymmetric introgression between them using a multilocus analysis

October 7, 2013 - 18:29 -- Open Access
Author(s): 
Luísa DP Rona, Carlos J Carvalho-Pinto and Alexandre A Peixoto
Reference: 
BMC Evolutionary Biology 2013, 13:207
MalariaWorld

The analyses were performed first comparing Florianópolis and Itatiaia, and then comparing the two putative sympatric incipient species from Itatiaia (Itatiaia A and Itatiaia B). The analysis revealed high FST values between Florianópolis and Itatiaia (considering Itatiaia A and B together) and also between the sympatric Itatiaia A and Itatiaia B, irrespective of their function.

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Cellular and humoral immune responses against the Plasmodium vivax MSP-119 malaria vaccine candidate in individuals living in an endemic area in north-eastern Amazon region of Brazil

September 18, 2013 - 12:23 -- Open Access
Author(s): 
Riccio EK, Totino PR, Pratt-Riccio LR, Ennes-Vidal V, Soares IS, Rodrigues MM, de Souza JM, Daniel-Ribeiro CT, de Ferreira-da-Cruz M
Reference: 
Malaria Journal 2013, 12:326 (16 September 2013)
MalariaWorld

The results presented here shows that PvMSP-119 was able to induce a high cellular activation, leading to production of TNF and emphasizes the high immunogenicity of PvMSP-119 in naturally exposed individuals and, therefore, its potential as a malaria vaccine candidate.

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Nightly biting cycles of malaria vectors in a heterogeneous transmission area of eastern Amazonian Brazil

August 12, 2013 - 09:53 -- Open Access
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Author(s): 
Zimmerman RH, Lounibos LP, Nishimura N, Galardo AK, Galardo CD, Arruda ME
Reference: 
Malaria Journal 2013, 12:262 (26 July 2013)
MalariaWorld

Analyses of co-efficients of variation, skewness and kurtosis facilitated quantitative comparisons of host-seeking activity patterns that differ among species, sites, villages, and dates.

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Natural Plasmodium infection in monkeys in the state of Rondonia (Brazilian Western Amazon)

June 5, 2013 - 12:45 -- Open Access
Author(s): 
da Silva Araújo M, Messias MR, Figueiró MR, Gil LH, Probst CM, de Medeiros Vidal N, Katsuragawa TH, Krieger MA, Pereira da Silva LH, Ozaki LS
Reference: 
Malaria Journal 2013, 12:180 (3 June 2013)
MalariaWorld

The rate of natural Plasmodium infection in monkeys in the Brazilian state of Rondonia is in line with previous surveys of simian malaria in the Amazon region.

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Natural infection in anopheline species and its implications for autochthonous malaria in the Atlantic forest in Brazil

March 10, 2013 - 14:04 -- Open Access
Author(s): 
Duarte AM, Pereira DM, de Paula MB, Fernandes A, Urbinatti PR, Ribeiro AF, Mello MH, Matos MO, Mucci LF, Fernandes LN, Natal D, Malafronte RS
Reference: 
Parasites & Vectors 2013, 6:58 (7 March 2013)
MalariaWorld

These results confirm that Anopheles (Kerteszia) cruzii plays an important role as a major Plasmodium vector. However, the finding of other naturally infected species may indicate that secondary vectors are also involved in the transmission of malaria in the study areas.

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Rob MacLennan: Jury voted with their 'gut'

December 12, 2012 - 10:31 -- Bart G.J. Knols

Yesterday, BBC's William Kremer published an excellent article about the myths surrounding ultrasounds as repellents against mosquitoes. We both talked many times about these myths and he researched the matter thoroughly. Nothing but praise for this piece of great journalism. But for us here at MalariaWorld the story isn't over yet, because the Cannes Lions Festival is simply waiting for the media storm to blow over and then move on with business as usual...

IL1B, IL4R, IL12RB1 and TNF gene polymorphisms are associated with plasmodium vivax malaria in Brazil

December 10, 2012 - 08:50 -- Open Access
Author(s): 
Sortica VA, Cunha MG, Ohnishi MD, Souza JM, Ribeiro-dos-Santos ÂK, Santos NP, Callegari-Jacques SM, Santos SE, Hutz MH
Reference: 
Malaria Journal 2012, 11:409 (7 December 2012)
MalariaWorld

Plasmodium vivax malaria pathophysiology is still poorly understood.

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