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Brazil

Anti-malarial activity and toxicity assessment of Himatanthus articulatus, a plant used to treat malaria in the Brazilian Amazon

March 31, 2015 - 17:38 -- Open Access
Author(s): 
Valdicley V Vale, Thyago C Vilhena, lávio De Vasconcelos, et al.
Reference: 
Malaria Journal 2015, 14:132 (27 March 2015)

The ethanol extract of H. articulatus proved to be promising as anti-malarial medicine and showed low toxicity.

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G6PD deficiency in male individuals infected by Plasmodium vivax malaria in the Brazilian Amazon: a cost study

March 25, 2015 - 15:47 -- Open Access
Author(s): 
Henry M Peixoto, Marcelo Brito, Gustavo Romero, Wuelton M Monteiro, Marcus de Lacerda, Maria de Oliveira
Reference: 
Malaria Journal 2015, 14:126 (24 March 2015)

The results indicate that the use of primaquine among men with G6PDd who are infected by P. vivax represents a heavy burden on the public health service of Brazil.

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Simian malaria in the Brazilian Atlantic forest: first description of natural infection of capuchin monkeys (Cebinae subfamily) by Plasmodium simium

March 7, 2015 - 09:54 -- Open Access
Author(s): 
Denise de Alvarenga, Anielle de Pina-Costa, Taís de Sousa, Alcides Pissinatti, Mariano G Zalis, Martha C Suaréz-Mutis, Ricardo Lourenço-de-Oliveira, Patrícia Brasil, Cláudio Daniel-Ribeiro, Cristiana de Brito
Reference: 
Malaria Journal 2015, 14:81 (18 February 2015)

The present study describes, for the first time, the natural infection of P. simium in capuchin monkeys from the Brazilian Atlantic Forest.

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Large-scale drivers of malaria and priority areas for prevention and control in the Brazilian Amazon region using a novel multi-pathogen geospatial model

December 5, 2014 - 15:48 -- Open Access
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Author(s): 
Denis Valle, Joanna M Tucker Lima
Reference: 
Malaria Journal 2014, 13:443 (20 November 2014)

This article provides several contributions. From a methodological perspective, the benefits of jointly modelling multiple pathogens for spatial predictions were illustrated.

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Evaluation of Naturally Acquired IgG Antibodies to a Chimeric and Non-Chimeric Recombinant Species of Plasmodium vivax Reticulocyte Binding Protein-1: Lack of Association with HLA-DRB1*/DQB1* in Malaria Exposed Individuals from the Brazilian Amazon

September 4, 2014 - 13:19 -- Open Access
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Author(s): 
Amanda Ribeiro Ferreira, Balwan Singh, Josué Da Costa Lima-Junior, et al.
Reference: 
PLoS ONE 9(8): e105828

The development of modular constructs that include antigenic regions targeted by protective immune responses is an attractive approach for subunit vaccine development.

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Unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: fact or artifact?

September 4, 2014 - 12:02 -- Open Access
Author(s): 
Mendrone A, Cerutti C, Levi JE, Boulos M, Arroyo Sanchez MC, dos Santos Malafronte R, Di Santi SM, Odone V
Reference: 
Malaria Journal 2014, 13 :336 (28 August 2014)

A study searching for Plasmodium vivax and Plasmodium falciparum DNA among blood donors from the non-endemic area in Brazil reported a rate of 7.41%. This number is at least three times higher than what has been observed in blood donors from the Amazon, an endemic area concentrating >99% of all malaria cases in Brazil.

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Imported malaria in a non-endemic area: the experience of the university of Campinas hospital in the Brazilian Southeast

July 30, 2014 - 07:35 -- Open Access
Author(s): 
Dos-Santos JC, Angerami RN, Castiñeiras CM, Lopes SC, Albrecht L, Garcia MT, Levy CE, Moretti ML, Lacerda MV, Costa FT
Reference: 
Malaria Journal 2014, 13 :280 (22 July 2014)

Severe malaria cases were frequent among imported cases in Brazil outside of the Amazon area.

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DDX39B (BAT1), TNF and IL6 gene polymorphisms and association with clinical outcomes of patients with Plasmodium vivax malaria

July 26, 2014 - 04:52 -- Open Access
Author(s): 
Mendonça VR, Souza LC, Garcia GC, Magalhães BM, Lacerda MV, Andrade BB, Gonçalves MS, Barral-Netto M
Reference: 
Malaria Journal 2014, 13 :278 (19 July 2014)

This is the first study to describe patients with DDX39B and IL6 SNPs who had vivax malaria.

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Assumed White Blood Cell Count of 8,000 Cells/μL Overestimates Malaria Parasite Density in the Brazilian Amazon

May 1, 2014 - 07:42 -- Open Access
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Author(s): 
Eduardo R. Alves-Junior, Luciano T. Gomes, Daniele Ribatski-Silva, Clebson Rodrigues J. Mendes, Fabio A. Leal-Santos, Luciano R. Simões, Marcia Beatriz C. Mello, Cor Jesus F. Fontes
Reference: 
PLoS ONE 9(4): e94193

Quantification of parasite density is an important component in the diagnosis of malaria infection.

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NOT Open Access | Influence of Plasmodium vivax malaria on the relations between the osmotic stability of human erythrocyte membrane and hematological and biochemical variables

March 3, 2014 - 07:58 -- NOT Open Access
Author(s): 
Rita de Cássia Mascarenhas Netto, Camila Fabbri, Mariana Vaini de Freitas, Morun Bernardino Neto, Mário Silva Garrote-Filho, Marcus Vinícius Guimarães Lacerda, Emerson Silva Lima & Nilson Penha-Silva
Reference: 
Parasitology Research, March 2014, Volume 113, Issue 3, pp 863-874

This study evaluated the influence of infection by Plasmodium vivax on the relations between hematological and biochemical variables and the osmotic stability of the erythrocyte membrane in a Brazilian Amazon population.

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