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Malaysia

The Duffy binding protein (PkDBPαII) of Plasmodium knowlesi from Peninsular Malaysia and Malaysian Borneo show different binding activity level to human erythrocytes

August 15, 2017 - 14:35 -- Open Access
Author(s): 
Khai Lone Lim, Amirah Amir, Yee Ling Lau and Mun Yik Fong
Reference: 
Malaria Journal 2017 16:331, 11 August 2017

This study is the first report of phenotypic difference between PkDBPαII haplotypes.

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Draft Genomes of Anopheles cracens and Anopheles maculatus: Comparison of Simian Malaria and Human Malaria Vectors in Peninsular Malaysia

July 19, 2016 - 15:15 -- Open Access
Author(s): 
Yee-Ling Lau, Wenn-Chyau Lee, Junhui Chen, Zhen Zhong, Jianbo Jian, Amirah Amir, Fei-Wen Cheong, Jia-Siang Sum, Mun-Yik Fong
Reference: 
PLoS ONE 11(6): e0157893

Anopheles cracens has been incriminated as the vector of human knowlesi malaria in peninsular Malaysia.

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Clustering and genetic differentiation of the normocyte binding protein (nbpxa) of Plasmodium knowlesi clinical isolates from Peninsular Malaysia and Malaysia Borneo

April 26, 2016 - 18:34 -- Open Access
Author(s): 
Md Atique Ahmed, Mun Yik Fong, Yee Ling Lau and Ruhani Yusof
Reference: 
Malaria Journal 2016 15:241, 26 April 2016

This study revealed the existence of three Pknbpxa types in Malaysia. Types 1 and 2 were found not only in Malaysian Borneo (Sarawak and Sabah) but also in Peninsular Malaysia.

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Genetic Diversity of Plasmodium falciparum Populations in Malaria Declining Areas of Sabah, East Malaysia

April 2, 2016 - 17:00 -- Open Access
Author(s): 
Mohd Ridzuan Mohd Abd Razak, Umi Rubiah Sastu, Noor Rain Abdullah, et al.
Reference: 
PLoS ONE 11(3): e0152415

Malaysia has a national goal to eliminate malaria by 2020. Understanding the genetic diversity of malaria parasites in residual transmission foci can provide invaluable information which may inform the intervention strategies used to reach elimination targets.

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Mutations of pvdhfr and pvdhps genes in vivax endemic-malaria areas in Kota Marudu and Kalabakan, Sabah

February 8, 2016 - 18:56 -- Open Access
Author(s): 
Umi Rubiah Sastu, Noor Rain Abdullah, Nor Azrina Norahmad, Muhammad Nor Farhan Saat, Prem Kumar Muniandy, Jenarun Jelip, Moizin Tikuson, Norsalleh Yusof and Hasidah Mohd Sidek
Reference: 
Malaria Journal 2016 15:63, 5 February 2016

The presence of triple and quintuple mutation combination suggest that the P. vivax isolates exhibit a high degree of resistant to sulfadoxine, pyrimethamine and sulfadoxine-pyrimethamine combination therapy.

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Diagnosis of an imported Plasmodium ovale wallikeri infection in Malaysia

January 12, 2016 - 16:50 -- Open Access
Author(s): 
Jonathan Liew, Rohela Mahmud, Lian Tan, Yee Lau
Reference: 
Malaria Journal 2016, 15:8 (6 January 2016)

Plasmodium ovale is rare and not exactly known to be autochthonous in Malaysia.

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Simian malaria in wild macaques: first report from Hulu Selangor district, Selangor, Malaysia

October 12, 2015 - 16:47 -- Open Access
Author(s): 
Rumana Akter, Indra Vythilingam, Loke Khaw, Rajes Qvist, Yvonne Lim, Frankie Sitam, Balan Venugopalan, Shamala Sekaran
Reference: 
Malaria Journal 2015, 14:386 (5 October 2015)

This study has provided evidence to elucidate the presence of transmission of malaria parasites among the local macaques in Hulu Selangor.

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Plasmodium knowlesi malaria an emerging public health problem in Hulu Selangor, Selangor Malaysia (2009-2013): epidemiologic and entomologic analysis

September 16, 2014 - 17:04 -- Open Access
Author(s): 
Vythilingam I, Lim YA, Mahmud R, et al.
Reference: 
Parasites & Vectors 2014, 7 :436 (15 September 2014)

In the present study, only An. introlatus was positive for oocysts. Kernel Density analysis showed that P. knowlesi hotspot areas overlapped with areas where the infected An. introlatus was discovered. This further strengthens the hypothesis that An. introlatusis is the vector for P. knowlesi in the Hulu Selangor district.

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High proportion of knowlesi malaria in recent malaria cases in Malaysia

May 14, 2014 - 12:13 -- Open Access
Author(s): 
Yusof R, Lau Y, Mahmud R, Fong M, Jelip J, Ngian H, Mustakim S, Mat Hussin H, Marzuki N, Mohd Ali M
Reference: 
Malaria Journal 2014, 13 :168 (3 May 2014)

In addition to Sabah and Sarawak, which have been known for high prevalence of P. knowlesi infection, the findings from this study highlight the widespread distribution of P. knowlesi in many Peninsular Malaysia states.

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Eliminating malaria in Malaysia: the role of partnerships between the public and commercial sectors in Sabah

January 27, 2014 - 13:43 -- Open Access
Tags: 
Author(s): 
Sanders KC, Rundi C, Jelip J, Rashman Y, Smith Gueye C, Gosling RD
Reference: 
Malaria Journal 2014, 13 :24 (21 January 2014)

Partnering with the commercial sector has been an essential operational strategy to support malaria elimination in Sabah.

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