There is no suspected or confirmed evidence of endemic artemisinin-resistant P. falciparum in this pre-elimination setting in Sabah, Malaysia.
This study is the first to report on the genetic diversity and natural selection of full-length pktrap.
This study is the first to report on the genetic diversity and natural selection of pkmsp1p.
Anopheles balabacensis of the Leucospyrus group has been confirmed as the primary knowlesi malaria vector in Sabah, Malaysian Borneo for some time now. Presently, knowlesi malaria is the only zoonotic simian malaria in Malaysia with a high prevalence recorded in the states of Sabah and Sarawak.
The macaque parasite Plasmodium knowlesi is a significant concern in Malaysia where cases of human infection are increasing.
Two malaria parasites of Southeast Asian macaques, Plasmodium knowlesi and P cynomolgi, can infect humans experimentally.
This study is the first report of phenotypic difference between PkDBPαII haplotypes.
Anopheles cracens has been incriminated as the vector of human knowlesi malaria in peninsular Malaysia.
This study revealed the existence of three Pknbpxa types in Malaysia. Types 1 and 2 were found not only in Malaysian Borneo (Sarawak and Sabah) but also in Peninsular Malaysia.
Malaysia has a national goal to eliminate malaria by 2020. Understanding the genetic diversity of malaria parasites in residual transmission foci can provide invaluable information which may inform the intervention strategies used to reach elimination targets.