The world's scientific and social network for malaria professionals
Subscribe to free Newsletter | 10033 malaria professionals are enjoying the free benefits of MalariaWorld today

Malaysia

Plasmodium falciparum artemisinin resistance monitoring in Sabah, Malaysia: in vivo therapeutic efficacy and kelch13 molecular marker surveillance

December 12, 2018 - 16:07 -- Open Access
Author(s): 
Matthew J. Grigg, Timothy William, Nicholas M. Anstey, et al.
Reference: 
Malaria Journal 2018 17:463, 10 December 2018

There is no suspected or confirmed evidence of endemic artemisinin-resistant P. falciparum in this pre-elimination setting in Sabah, Malaysia.

Country: 
Medical Condition: 

Diversity and natural selection on the thrombospondin-related adhesive protein (TRAP) gene of Plasmodium knowlesi in Malaysia

July 31, 2018 - 15:29 -- Open Access
Author(s): 
Md Atique Ahmed, Yee Ling Lau and Fu-Shi Quan
Reference: 
Malaria Journal 2018 17:274, 27 July 2018

This study is the first to report on the genetic diversity and natural selection of full-length pktrap.

Country: 

Genetic diversity and natural selection of Plasmodium knowlesi merozoite surface protein 1 paralog gene in Malaysia

March 15, 2018 - 07:00 -- Open Access
Author(s): 
Md Atique Ahmed, Muh Fauzi and Eun-Taek Han
Reference: 
Malaria Journal 2018 17:115, 14 March 2018

This study is the first to report on the genetic diversity and natural selection of pkmsp1p.

Country: 

Phylogenetic analysis of simian Plasmodium spp. infecting Anopheles balabacensis Baisas in Sabah, Malaysia

October 12, 2017 - 15:24 -- Open Access
Author(s): 
Tock H. Chua, Benny O. Manin, Sylvia Daim, Indra Vythilingam, Chris Drakeley
Reference: 
PLoS Negl Trop Dis 11(10): e0005991

Background

Anopheles balabacensis of the Leucospyrus group has been confirmed as the primary knowlesi malaria vector in Sabah, Malaysian Borneo for some time now. Presently, knowlesi malaria is the only zoonotic simian malaria in Malaysia with a high prevalence recorded in the states of Sabah and Sarawak.

Methodology/Principal findings

Country: 

Analysis of nuclear and organellar genomes of Plasmodium knowlesi in humans reveals ancient population structure and recent recombination among host-specific subpopulations

October 3, 2017 - 17:18 -- Open Access
Author(s): 
Ernest Diez Benavente, Paola Florez de Sessions, Taane G. Clark, et al.
Reference: 
PLoS Genet 13(9): e1007008

The macaque parasite Plasmodium knowlesi is a significant concern in Malaysia where cases of human infection are increasing.

Country: 

NOT Open Access | Strict tropism for CD71+/CD234+ human reticulocytes limits the zoonotic potential of Plasmodium cynomolgi

September 23, 2017 - 06:21 -- NOT Open Access
Author(s): 
Varakorn Kosaisavee, Rossarin Suwanarusk, Bruce Russell, et al.
Reference: 
Blood Volume: 130, Issue: 11, Pages: 1357-1363

Two malaria parasites of Southeast Asian macaques, Plasmodium knowlesi and P cynomolgi, can infect humans experimentally.

Country: 

The Duffy binding protein (PkDBPαII) of Plasmodium knowlesi from Peninsular Malaysia and Malaysian Borneo show different binding activity level to human erythrocytes

August 15, 2017 - 14:35 -- Open Access
Author(s): 
Khai Lone Lim, Amirah Amir, Yee Ling Lau and Mun Yik Fong
Reference: 
Malaria Journal 2017 16:331, 11 August 2017

This study is the first report of phenotypic difference between PkDBPαII haplotypes.

Country: 

Draft Genomes of Anopheles cracens and Anopheles maculatus: Comparison of Simian Malaria and Human Malaria Vectors in Peninsular Malaysia

July 19, 2016 - 15:15 -- Open Access
Author(s): 
Yee-Ling Lau, Wenn-Chyau Lee, Junhui Chen, Zhen Zhong, Jianbo Jian, Amirah Amir, Fei-Wen Cheong, Jia-Siang Sum, Mun-Yik Fong
Reference: 
PLoS ONE 11(6): e0157893

Anopheles cracens has been incriminated as the vector of human knowlesi malaria in peninsular Malaysia.

Country: 

Clustering and genetic differentiation of the normocyte binding protein (nbpxa) of Plasmodium knowlesi clinical isolates from Peninsular Malaysia and Malaysia Borneo

April 26, 2016 - 18:34 -- Open Access
Author(s): 
Md Atique Ahmed, Mun Yik Fong, Yee Ling Lau and Ruhani Yusof
Reference: 
Malaria Journal 2016 15:241, 26 April 2016

This study revealed the existence of three Pknbpxa types in Malaysia. Types 1 and 2 were found not only in Malaysian Borneo (Sarawak and Sabah) but also in Peninsular Malaysia.

Country: 

Genetic Diversity of Plasmodium falciparum Populations in Malaria Declining Areas of Sabah, East Malaysia

April 2, 2016 - 17:00 -- Open Access
Author(s): 
Mohd Ridzuan Mohd Abd Razak, Umi Rubiah Sastu, Noor Rain Abdullah, et al.
Reference: 
PLoS ONE 11(3): e0152415

Malaysia has a national goal to eliminate malaria by 2020. Understanding the genetic diversity of malaria parasites in residual transmission foci can provide invaluable information which may inform the intervention strategies used to reach elimination targets.

Country: 

Pages

Subscribe to RSS - Malaysia