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Bukina Faso

Open Access | De Novo Transcriptome Sequencing in Anopheles funestus Using Illumina RNA-Seq Technology

December 16, 2010 - 06:38 -- Kabogo Ndegwa
Author(s): 
Jacob E. Crawford, Wamdaogo M. Guelbeogo, Antoine Sanou, Alphonse Traoré, Kenneth D. Vernick, N'Fale Sagnon, Brian P. Lazzaro
Reference: 
PLoS ONE 5(12): e14202

We developed a pipeline that makes de novo transcriptome sequencing possible in virtually any organism at a very reasonable cost ($6,300 in sequencing costs in our case).

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Open Access | Different delivery mechanisms for insecticide-treated nets in rural Burkina Faso: a provider's perspective

December 10, 2010 - 05:42 -- Kabogo Ndegwa
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Author(s): 
Beiersmann C, De Allegri M, Tiendrebeogo J, Ye M, Jahn A, Mueller O
Reference: 
Malaria Journal 2010, 9:352 (4 December 2010)

The combination of ITN free distribution and social marketing was in general well accepted by the different providers.

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Open Access | Intermittent preventive treatment of malaria with sulphadoxine-pyrimethamine during pregnancy in Burkina Faso: effect of adding a third dose to the standard two-dose regimen on low birth weight, anaemia and pregnancy outcomes

November 17, 2010 - 08:13 -- Kabogo Ndegwa
Author(s): 
Innocent Valea, Halidou Tinto, Maxime K Drabo, Lieven Huybregts, Marie-Claire Henry, Dominique Roberfroid, Robert T Guiguemde, Patrick Kolsteren, Umberto D'Alessandro, Micronutriments-Sante de la Mere et de l'Enfant MISAME/FSP study group
Reference: 
Malaria Journal 2010, 9:324 (12 November 2010)

The risk of LBW and severe anaemia tended to be lower in the SP3 group, though this was not statistically significant, probably due to the low uptake of the intervention which reduced the power of the study.

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The effects of a pre-season treatment with effective antimalarials on subsequent malaria morbidity in under five-year-old children living in high and seasonal malaria transmission area of Burkina Faso (pages 1315–1321)

October 22, 2010 - 09:37 -- Kabogo Ndegwa
Author(s): 
Alphonse Ouédraogo, Alfred B. Tiono, Amidou Diarra, Issa O. Nébié, Amadou T. Konaté and Sodiomon B. Sirima
Reference: 
Tropical Medicine & International Health, Volume 15, Issue 11, pages 1315–1321, November 2010

Our findings suggest that the radical clearance of parasitemia with AL may increase susceptibility to malaria infection and clinical malaria episodes.

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Mechanisms of Resistance: Selection of Known Plasmodium falciparum Resistance-Mediating Polymorphisms by Artemether-Lumefantrine and Amodiaquine- Sulfadoxine-Pyrimethamine but Not Dihydroartemisinin- Piperaquine in Burkina Faso

April 20, 2010 - 09:01 -- Kabogo Ndegwa
Author(s): 
Anyirékun Fabrice Somé, Yves Y. Séré, Christian Dokomajilar, Issaka Zongo, Noël Rouamba, Bryan Greenhouse, Jean-Bosco Ouédraogo, and Philip J. Rosenthal
Reference: 
Antimicrobial Agents and Chemotherapy, May 2010, p. 1949-1954, Vol. 54, No. 5

Artemether-lumefantrine (AL), dihydroartemisinin-piperaquine (DP), and amodiaquine-sulfadoxine-pyrimethamine (AQ-SP) offer excellent antimalarial efficacy but may select for parasite polymorphisms that decrease drug sensitivity. We evaluated the selection of known polymorphisms in genes encoding putative transporters (pfcrt and pfmdr1) and SP targets (pfdhfr and pfdhps) in parasites that caused new infections within 42 days of therapy for uncomplicated falciparum malaria in Burkina Faso.

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